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| | actb | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (347 aa) |
| | actn1 | Uncharacterized protein. (890 aa) |
| | pak3 | Non-specific serine/threonine protein kinase. (564 aa) |
| | pip5k1a | PIPK domain-containing protein. (468 aa) |
| | RDX | Radixin. (602 aa) |
| | fgf1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | diaph3 | Attractin. (1150 aa) |
| | pak4 | Non-specific serine/threonine protein kinase. (665 aa) |
| | abi2 | Uncharacterized protein. (544 aa) |
| | gna13 | LOC100145489 protein. (377 aa) |
| | arpc2 | Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (299 aa) |
| | pik3cb | Solute carrier family 27 member 6; Belongs to the PI3/PI4-kinase family. (1085 aa) |
| | cfl1 | Cofilin-1; May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Required for formation of the cleavage furrow during cytokinesis. (168 aa) |
| | fgf16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa) |
| | LOC105947943 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa) |
| | sos2 | Ornithine carbamoyltransferase. (1333 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1216 aa) |
| | ITGB4 | Integrin beta. (1835 aa) |
| | cyfip2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1266 aa) |
| | pik3r2 | Uncharacterized protein. (719 aa) |
| | LOC108644441 | Gelsolin-like domain-containing protein. (124 aa) |
| | ITGA11 | Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1171 aa) |
| | arpc1a | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (381 aa) |
| | rac2 | Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2). (192 aa) |
| | fgf22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (175 aa) |
| | nras | Novel gene of the neuroblastoma RAS viral (V-ras) oncogene homolog family. (189 aa) |
| | CHRM1 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (521 aa) |
| | ppp1cb | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity (By similarity). (327 aa) |
| | MYLK4 | Myosin light chain kinase family member 4. (852 aa) |
| | arpc5l | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (152 aa) |
| | fgf3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (236 aa) |
| | rhoa.2 | Nuclear receptor binding SET domain protein 3. (193 aa) |
| | egf | Uncharacterized protein. (1051 aa) |
| | myl2 | Adaptor related protein complex 5 subunit zeta 1. (245 aa) |
| | fgf2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa) |
| | ppp1r12b | PRKG1_interact domain-containing protein. (186 aa) |
| | itga1 | Tetratricopeptide repeat domain 37; Belongs to the integrin alpha chain family. (1132 aa) |
| | itga2 | Leucine-rich repeats and immunoglobulin like domains 2; Belongs to the integrin alpha chain family. (1177 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (718 aa) |
| | pak1 | Non-specific serine/threonine protein kinase. (521 aa) |
| | crk | Multivesicular body subunit 12B. (297 aa) |
| | ITGB2 | Integrin beta. (774 aa) |
| | hras | Chloride channel accessory 1 gene 1. (217 aa) |
| | apc | Zinc finger DHHC-type containing 1. (2833 aa) |
| | mapk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa) |
| | sos1 | Organic solute transporter subunit alpha. (1329 aa) |
| | lpar2 | Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (344 aa) |
| | pip4k2c | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2). (484 aa) |
| | myl9 | LOC100124811 protein. (172 aa) |
| | actg1 | Actin, cytoplasmic 2, N-terminally processed; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. (375 aa) |
| | pak2 | Non-specific serine/threonine protein kinase. (518 aa) |
| | myl12b | Uncharacterized protein. (173 aa) |
| | pdgfb-2 | Frizzled related protein; Belongs to the PDGF/VEGF growth factor family. (240 aa) |
| | bri3bp-2 | Non-specific serine/threonine protein kinase. (754 aa) |
| | chrm5 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (525 aa) |
| | fgf8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | arhgap35 | Bora, aurora kinase A activator. (1472 aa) |
| | iqgap1 | F-box and leucine-rich repeat protein 16. (1663 aa) |
| | itgav | RAB5B, member RAS oncogene family; Belongs to the integrin alpha chain family. (1034 aa) |
| | PFN4 | Profilin; Belongs to the profilin family. (128 aa) |
| | src | Tyrosine-protein kinase. (557 aa) |
| | ssh3 | RAN binding protein 1. (688 aa) |
| | mras | Thrombospondin 3. (208 aa) |
| | apc2 | Transmembrane protein 11. (2325 aa) |
| | itga8 | Pyrroline-5-carboxylate reductase family, member 1; Belongs to the integrin alpha chain family. (1081 aa) |
| | ins | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa) |
| | fgf20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (274 aa) |
| | rac3 | NGFI-A binding protein 2 (EGR1 binding protein 2). (192 aa) |
| | fgf9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1022 aa) |
| | lpar1 | LOC100124893 protein; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | actn4 | Uncharacterized protein. (926 aa) |
| | msn | Homogentisate 1,2-dioxygenase. (591 aa) |
| | spata13 | Uncharacterized protein. (1225 aa) |
| | LOC100485322 | Phosphoglycerate mutase 1. (545 aa) |
| | baiap2 | Uncharacterized protein. (554 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1272 aa) |
| | wasf2 | Forkhead box Q1. (484 aa) |
| | map2k1 | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (395 aa) |
| | slc9a1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (792 aa) |
| | dstn | Solute carrier family 1 member 2; Belongs to the actin-binding proteins ADF family. (153 aa) |
| | kras | V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (186 aa) |
| | arhgef4 | Bromodomain containing 8. (660 aa) |
| | pikfyve | Uncharacterized protein. (2104 aa) |
| | f2r | Dab, mitogen-responsive phosphoprotein, homolog 2; Belongs to the G-protein coupled receptor 1 family. (416 aa) |
| | ezr | FERM domain-containing protein. (621 aa) |
| | mylkl | Uncharacterized protein. (855 aa) |
| | itga6 | Serine/arginine repetitive matrix 2; Belongs to the integrin alpha chain family. (1095 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (908 aa) |
| | arpc1b | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (383 aa) |
| | cfb-2 | Complement factor B. (329 aa) |
| | LOC101731775 | VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1124 aa) |
| | pdgfra | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1096 aa) |
| | LOC100493774 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2011 aa) |
| | mylpf | Uncharacterized protein. (175 aa) |
| | f2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (607 aa) |
| | raf1 | Zona pellucida glycoprotein 4. (305 aa) |
| | fgd3 | Uncharacterized protein. (896 aa) |
| | LOC100488540 | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (357 aa) |
| | fgf19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa) |
| | fgf4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa) |
| | or2t29 | Olfactory receptor family 2 subfamily T member 29. (179 aa) |
| | LOC100487727 | Protein phosphatase 1 regulatory subunit. (814 aa) |
| | trpm2l | Transient receptor potential cation channel, subfamily M, member 2 like; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | arpc5 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (150 aa) |
| | rras | Transducin like enhancer of split 1. (203 aa) |
| | cdc42 | Uncharacterized protein. (212 aa) |
| | wasf1 | Wasf1 protein. (558 aa) |
| | cxcl12 | Stromal cell-derived factor 1; Chemoattractant. Activates the C-X-C chemokine receptor cxcr4 to induce a rapid and transient rise in the level of intracellular calcium ions, and chemotaxis. Signaling with cxcr4 mediates the directional movement of mesodermal cells during gastrulation. Binds to the allosteric site (site 2) of integrins and activates them in a cxcr4-independent manner. (109 aa) |
| | ppp1cc | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Promotes nuclear envelope reassembly by targeting nuclear membrane vesicles to chromatin at the end of mitosis. Acts by dephosphorylating membrane proteins such as lamin B receptor (lbr) to regulate the binding of membrane proteins to chromatin (By similarity); Belongs to the PPP phosphatase family. PP-1 subfamily. (329 aa) |
| | arpc3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (181 aa) |
| | PIP5K1B | Phosphatidylinositol-4-phosphate 5-kinase type 1 beta. (585 aa) |
| | SSH1 | Slingshot protein phosphatase 1. (975 aa) |
| | fgf23.2 | Leucine-rich repeat LGI family member 4; Belongs to the heparin-binding growth factors family. (254 aa) |
| | fgf10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa) |
| | fgf23.1 | Uncharacterized protein; Belongs to the heparin-binding growth factors family. (249 aa) |
| | fgf6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa) |
| | KNG1 | Kininogen 1. (588 aa) |
| | rac1 | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (192 aa) |
| | brk1 | Anoctamin 9. (170 aa) |
| | limk2 | Exocyst complex component 6. (585 aa) |
| | tmsb4x | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (48 aa) |
| | itgb1 | Integrin beta; Belongs to the integrin beta chain family. (808 aa) |
| | MOS | MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (355 aa) |
| | fgfr4 | Fibroblast growth factor receptor. (833 aa) |
| | ITGA9 | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1045 aa) |
| | rhoa | Ras homolog gene family, member A. (193 aa) |
| | CHRM2 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (470 aa) |
| | lpar4 | G protein-coupled receptor 23; Belongs to the G-protein coupled receptor 1 family. (350 aa) |
| | pdgfa | Uncharacterized protein; Belongs to the PDGF/VEGF growth factor family. (308 aa) |
| | vav1 | V-rel avian reticuloendotheliosis viral oncogene homolog. (836 aa) |
| | bcar1 | SH3 domain-containing protein. (951 aa) |
| | PDGFD | Platelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (389 aa) |
| | arhgef12 | Retinoic acid induced 2. (1438 aa) |
| | Mylk | Uncharacterized protein. (307 aa) |
| | pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1067 aa) |
| | pfn2 | Profilin; Belongs to the profilin family. (140 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (726 aa) |
| | FGD1 | FYVE, RhoGEF and PH domain containing 1. (923 aa) |
| | NCKAP1 | NCK associated protein 1. (1134 aa) |
| | met-2 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (560 aa) |
| | itgb3 | Integrin beta; Belongs to the integrin beta chain family. (800 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1030 aa) |
| | cxcr4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine cxcl12/sdf-1. Transduces a signal by increasing the intracellular calcium ion level. Signaling with cxcl12/sdf-1 mediates the directional movement of mesodermal cells during gastrulation. May play a role in the migration of embryonic presumptive primordial germ cells (pPGCs). May also be involved in regulating migration of hematopoietic stem cells into the larval liver (By similarity). (358 aa) |
| | bdkrb2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | rhoc | Calponin 3, acidic. (193 aa) |
| | rock2 | Mediator of RNA polymerase II transcription subunit 18; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1461 aa) |
| | scin | Kinetochore protein NDC80 homolog. (761 aa) |
| | LOC108644475 | SH3 and PX domains 2B. (715 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1046 aa) |
| | pip4k2a | Chromosome 11 open reading frame 54. (470 aa) |
| | fgfr3 | Fibroblast growth factor receptor. (829 aa) |
| | gng12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | myl7 | Trinucleotide repeat containing 6C. (173 aa) |
| | ssh2 | FERM and PDZ domain containing 3. (1419 aa) |
| | pip4k2b | Laeverin. (426 aa) |
| | ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor 6. (765 aa) |
| | fgfr1 | Fibroblast growth factor receptor. (827 aa) |
| | fn1 | Fibronectin 1. (2475 aa) |
| | cfl2 | Cofilin-2; Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity); Belongs to the actin-binding proteins ADF family. (167 aa) |
| | pik3r3 | Phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (P55, gamma). (461 aa) |
| | wasl | Wiskott-Aldrich syndrome-like. (511 aa) |
| | pip5k1c | PIPK domain-containing protein. (688 aa) |
| | MYH11 | Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1982 aa) |
| | itgb6 | Integrin beta; Belongs to the integrin beta chain family. (782 aa) |
| | pak6 | Non-specific serine/threonine protein kinase. (673 aa) |
| | fgf7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | DOCK1 | Dedicator of cytokinesis 1; Belongs to the DOCK family. (1859 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1122 aa) |
| | myl10 | LOC100170437 protein. (168 aa) |
