STRINGSTRING
polA polA AHI57383.1 AHI57383.1 dnaX dnaX AHI57391.1 AHI57391.1 AHI57415.1 AHI57415.1 rpoB rpoB AHI57449.1 AHI57449.1 rpoC rpoC AHI57534.1 AHI57534.1 pnp pnp AHI57634.1 AHI57634.1 coaD coaD rpoA rpoA AHI57735.1 AHI57735.1 nadD nadD AHI58067.1 AHI58067.1 AHI58216.1 AHI58216.1 AHI58217.1 AHI58217.1 dnaG dnaG polC polC AHI58312.1 AHI58312.1 AHI58436.1 AHI58436.1 thiI thiI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polAHypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (869 aa)
AHI57383.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa)
dnaXHypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (715 aa)
AHI57391.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (280 aa)
AHI57415.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. (184 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1296 aa)
AHI57449.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (75 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1157 aa)
AHI57534.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (322 aa)
pnpPolynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (701 aa)
AHI57634.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (168 aa)
coaDHypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (140 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (317 aa)
AHI57735.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (329 aa)
nadDHypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (366 aa)
AHI58067.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (112 aa)
AHI58216.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (169 aa)
AHI58217.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (146 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (617 aa)
polCHypothetical protein; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1457 aa)
AHI58312.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CDS family. (360 aa)
AHI58436.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1014 aa)
thiIHypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (399 aa)
Your Current Organism:
Spiroplasma mirum
NCBI taxonomy Id: 838561
Other names: S. mirum ATCC 29335, Spiroplasma mirum ATCC 29335, Spiroplasma mirum SMCA, Spiroplasma mirum str. ATCC 29335, Spiroplasma mirum strain ATCC 29335
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