STRINGSTRING
AHI58711.1 AHI58711.1 AHI58710.1 AHI58710.1 AHI58707.1 AHI58707.1 AHI58703.1 AHI58703.1 AHI58700.1 AHI58700.1 AHI58688.1 AHI58688.1 AHI58685.1 AHI58685.1 glyA glyA AHI58632.1 AHI58632.1 AHI58624.1 AHI58624.1 AHI58618.1 AHI58618.1 AHI58614.1 AHI58614.1 AHI58613.1 AHI58613.1 AHI58612.1 AHI58612.1 AHI58604.1 AHI58604.1 gatB gatB AHI58573.1 AHI58573.1 AHI58572.1 AHI58572.1 proS proS tyrS tyrS AHI58547.1 AHI58547.1 prs prs uvrB uvrB AHI58526.1 AHI58526.1 pgk pgk AHI58522.1 AHI58522.1 secA secA uvrA uvrA AHI58513.1 AHI58513.1 AHI58510.1 AHI58510.1 AHI58496.1 AHI58496.1 AHI58495.1 AHI58495.1 guaA guaA AHI58487.1 AHI58487.1 AHI58486.1 AHI58486.1 AHI58485.1 AHI58485.1 pstB pstB AHI58471.1 AHI58471.1 AHI58470.1 AHI58470.1 AHI58469.1 AHI58469.1 AHI58468.1 AHI58468.1 AHI58462.1 AHI58462.1 rsgA rsgA AHI58459.1 AHI58459.1 thiI thiI ackA ackA trpS trpS AHI58413.1 AHI58413.1 AHI58375.1 AHI58375.1 AHI58367.1 AHI58367.1 argS argS AHI58347.1 AHI58347.1 engB engB AHI58326.1 AHI58326.1 AHI58325.1 AHI58325.1 AHI58323.1 AHI58323.1 ffh ffh pyrH pyrH dxr dxr era era glyQS glyQS AHI58287.1 AHI58287.1 AHI58265.1 AHI58265.1 AHI58258.1 AHI58258.1 AHI58257.1 AHI58257.1 AHI58251.1 AHI58251.1 AHI58240.1 AHI58240.1 AHI58239.1 AHI58239.1 AHI58235.1 AHI58235.1 AHI58230.1 AHI58230.1 AHI58229.1 AHI58229.1 AHI58226.1 AHI58226.1 coaX coaX AHI58217.1 AHI58217.1 AHI58216.1 AHI58216.1 nrdI nrdI AHI57372.1 AHI57372.1 lepA lepA AHI58209.1 AHI58209.1 AHI58202.1 AHI58202.1 pheS pheS pheT pheT AHI58183.1 AHI58183.1 AHI58182.1 AHI58182.1 ftsZ ftsZ ileS ileS pfkA pfkA AHI58161.1 AHI58161.1 AHI58160.1 AHI58160.1 thrS thrS AHI58137.1 AHI58137.1 AHI58131.1 AHI58131.1 mnmA mnmA AHI58112.1 AHI58112.1 AHI58111.1 AHI58111.1 udk udk AHI58092.1 AHI58092.1 AHI58088.1 AHI58088.1 miaA miaA AHI58072.1 AHI58072.1 azoR azoR AHI58021.1 AHI58021.1 parC parC parE parE aspS aspS hisS hisS AHI57997.1 AHI57997.1 AHI57967.1 AHI57967.1 alaS alaS nadD nadD AHI57922.1 AHI57922.1 nadE nadE obg obg AHI57878.1 AHI57878.1 lon lon AHI57868.1 AHI57868.1 AHI57866.1 AHI57866.1 AHI57853.1 AHI57853.1 AHI57852.1 AHI57852.1 AHI57851.1 AHI57851.1 AHI57850.1 AHI57850.1 valS valS AHI57838.1 AHI57838.1 AHI57822.1 AHI57822.1 AHI57812.1 AHI57812.1 AHI57804.1 AHI57804.1 AHI57803.1 AHI57803.1 AHI57800.1 AHI57800.1 AHI57793.1 AHI57793.1 AHI57792.1 AHI57792.1 engA engA cmk cmk AHI57754.1 AHI57754.1 AHI57745.1 AHI57745.1 AHI57744.1 AHI57744.1 AHI57739.1 AHI57739.1 AHI57735.1 AHI57735.1 AHI57734.1 AHI57734.1 asnS asnS AHI57719.1 AHI57719.1 adk adk AHI57353.1 AHI57353.1 AHI57690.1 AHI57690.1 cbiO-2 cbiO-2 cbiO cbiO AHI57677.1 AHI57677.1 coaD coaD purA purA pyrG pyrG gltX gltX ychF ychF AHI57615.1 AHI57615.1 AHI57605.1 AHI57605.1 AHI57604.1 AHI57604.1 cysS cysS mnmG mnmG metG metG AHI57592.1 AHI57592.1 leuS leuS dnaJ dnaJ dnaK dnaK AHI57565.1 AHI57565.1 AHI57554.1 AHI57554.1 AHI57546.1 AHI57546.1 AHI57545.1 AHI57545.1 AHI57544.1 AHI57544.1 AHI57543.1 AHI57543.1 AHI57541.1 AHI57541.1 AHI57539.1 AHI57539.1 AHI57538.1 AHI57538.1 potA potA metK metK ftsY ftsY atpD atpD atpG atpG atpA atpA upp upp AHI57464.1 AHI57464.1 AHI57463.1 AHI57463.1 tuf tuf fusA fusA AHI57444.1 AHI57444.1 tdk tdk AHI57428.1 AHI57428.1 AHI57427.1 AHI57427.1 tilS tilS tmk tmk dnaX dnaX serS serS gyrA gyrA gyrB gyrB dnaA dnaA AHI57381.1 AHI57381.1 AHI57421.1 AHI57421.1 AHI57412.1 AHI57412.1 lysS lysS mnmE mnmE ftsH ftsH AHI57407.1 AHI57407.1 AHI57411.1 AHI57411.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AHI58711.1Rod shape-determining protein MreB; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (350 aa)
AHI58710.1Rod shape-determining protein MreB; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (349 aa)
AHI58707.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (352 aa)
AHI58703.1Rod shape-determining protein MreB; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (348 aa)
AHI58700.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (249 aa)
AHI58688.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TPP enzyme family. (555 aa)
AHI58685.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (885 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
AHI58632.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (608 aa)
AHI58624.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (271 aa)
AHI58618.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (181 aa)
AHI58614.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (52 aa)
AHI58613.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (50 aa)
AHI58612.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (79 aa)
AHI58604.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (109 aa)
gatBHypothetical protein; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (480 aa)
AHI58573.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (144 aa)
AHI58572.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (140 aa)
proSHypothetical protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (474 aa)
tyrSHypothetical protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (412 aa)
AHI58547.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (899 aa)
prsPhosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (340 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (654 aa)
AHI58526.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the HPrK/P family. (308 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phosphoglycerate kinase family. (411 aa)
AHI58522.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (647 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (796 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (946 aa)
AHI58513.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (376 aa)
AHI58510.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (296 aa)
AHI58496.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (291 aa)
AHI58495.1Hypothetical protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (292 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (510 aa)
AHI58487.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (453 aa)
AHI58486.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (448 aa)
AHI58485.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (418 aa)
pstBPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (269 aa)
AHI58471.1Hypothetical protein; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. (502 aa)
AHI58470.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (118 aa)
AHI58469.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (65 aa)
AHI58468.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (101 aa)
AHI58462.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (336 aa)
rsgAHypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (293 aa)
AHI58459.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (206 aa)
thiIHypothetical protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (399 aa)
ackAHypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (340 aa)
AHI58413.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CoaE family. (191 aa)
AHI58375.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (328 aa)
AHI58367.1Hypothetical protein; Essential for recycling GMP and indirectly, cGMP. (158 aa)
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (557 aa)
AHI58347.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (189 aa)
engBHypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (197 aa)
AHI58326.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (82 aa)
AHI58325.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (60 aa)
AHI58323.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (82 aa)
ffhSignal recognition particle protein Srp54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (447 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
dxrHypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (381 aa)
eraGTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (298 aa)
glyQSglycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (458 aa)
AHI58287.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (235 aa)
AHI58265.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (456 aa)
AHI58258.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (138 aa)
AHI58257.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (89 aa)
AHI58251.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (415 aa)
AHI58240.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (115 aa)
AHI58239.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (105 aa)
AHI58235.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (141 aa)
AHI58230.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (55 aa)
AHI58229.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (160 aa)
AHI58226.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the formate--tetrahydrofolate ligase family. (534 aa)
coaXHypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa)
AHI58217.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (146 aa)
AHI58216.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (169 aa)
nrdIHypothetical protein; Probably involved in ribonucleotide reductase function. (151 aa)
AHI57372.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (719 aa)
lepAHypothetical protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (381 aa)
AHI58209.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (250 aa)
AHI58202.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (134 aa)
pheSHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (345 aa)
pheTHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (796 aa)
AHI58183.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (54 aa)
AHI58182.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (138 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (409 aa)
ileSHypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (904 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)
AHI58161.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (76 aa)
AHI58160.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the pyruvate kinase family. (416 aa)
thrSHypothetical protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (640 aa)
AHI58137.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (447 aa)
AHI58131.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (642 aa)
mnmAHypothetical protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (377 aa)
AHI58112.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (451 aa)
AHI58111.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (36 aa)
udkHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (216 aa)
AHI58092.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (245 aa)
AHI58088.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (362 aa)
miaAHypothetical protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (311 aa)
AHI58072.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (311 aa)
azoRAzoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (200 aa)
AHI58021.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (274 aa)
parCHypothetical protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily. (1039 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (646 aa)
aspSHypothetical protein; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (581 aa)
hisSHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (418 aa)
AHI57997.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (68 aa)
AHI57967.1Hypothetical protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (595 aa)
alaSHypothetical protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (914 aa)
nadDHypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (366 aa)
AHI57922.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (140 aa)
nadEHypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (246 aa)
obgHypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (434 aa)
AHI57878.1Rod shape-determining protein MreB; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (346 aa)
lonLon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (779 aa)
AHI57868.1Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (203 aa)
AHI57866.1Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (182 aa)
AHI57853.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (93 aa)
AHI57852.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (84 aa)
AHI57851.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (41 aa)
AHI57850.1Hypothetical protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (50 aa)
valSHypothetical protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (880 aa)
AHI57838.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DEAD box helicase family. (427 aa)
AHI57822.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (219 aa)
AHI57812.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (538 aa)
AHI57804.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (84 aa)
AHI57803.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (164 aa)
AHI57800.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (935 aa)
AHI57793.1Ribonucleotide-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (785 aa)
AHI57792.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (56 aa)
engAGTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (438 aa)
cmkHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (223 aa)
AHI57754.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (491 aa)
AHI57745.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (139 aa)
AHI57744.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (55 aa)
AHI57739.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (461 aa)
AHI57735.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (329 aa)
AHI57734.1NADH oxidase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (452 aa)
asnSasparaginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (455 aa)
AHI57719.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (734 aa)
adkHypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa)
AHI57353.1DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (455 aa)
AHI57690.1Hypothetical protein; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (672 aa)
cbiO-2Cobalt ABC transporter ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (303 aa)
cbiOCobalt ABC transporter ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. (288 aa)
AHI57677.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FtsK/SpoIIIE/SftA family. (977 aa)
coaDHypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (140 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (433 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa)
gltXglutamyl-tRNA synthase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (487 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
AHI57615.1Sporulation initiation inhibitor Soj; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (256 aa)
AHI57605.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (113 aa)
AHI57604.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (193 aa)
cysSHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-I aminoacyl-tRNA synthetase family. (440 aa)
mnmGHypothetical protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (627 aa)
metGHypothetical protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (529 aa)
AHI57592.1Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (263 aa)
leuSleucyl-tRNA synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-I aminoacyl-tRNA synthetase family. (806 aa)
dnaJHypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dna [...] (382 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (600 aa)
AHI57565.1ATPase AAA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ClpA/ClpB family. (713 aa)
AHI57554.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (179 aa)
AHI57546.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (90 aa)
AHI57545.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (46 aa)
AHI57544.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (73 aa)
AHI57543.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (73 aa)
AHI57541.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (82 aa)
AHI57539.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (135 aa)
AHI57538.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (122 aa)
potASpermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (350 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (384 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (328 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (464 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (285 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (523 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa)
AHI57464.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (177 aa)
AHI57463.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (46 aa)
tufElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa)
fusAElongation factor P; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (694 aa)
AHI57444.1Sugar ABC transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (523 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (194 aa)
AHI57428.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (345 aa)
AHI57427.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (281 aa)
tilSHypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (445 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (215 aa)
dnaXHypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (715 aa)
serSHypothetical protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (422 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (813 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (642 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (450 aa)
AHI57381.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (47 aa)
AHI57421.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (99 aa)
AHI57412.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (82 aa)
lysSlysyl-tRNA synthetase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-II aminoacyl-tRNA synthetase family. (500 aa)
mnmEHypothetical protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (448 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (690 aa)
AHI57407.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (308 aa)
AHI57411.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (91 aa)
Your Current Organism:
Spiroplasma mirum
NCBI taxonomy Id: 838561
Other names: S. mirum ATCC 29335, Spiroplasma mirum ATCC 29335, Spiroplasma mirum SMCA, Spiroplasma mirum str. ATCC 29335, Spiroplasma mirum strain ATCC 29335
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