STRINGSTRING
CDK3 CDK3 UY3_17734 UY3_17734 RFC3 RFC3 DBF4 DBF4 MCM8 MCM8 UY3_10496 UY3_10496 RCBTB1 RCBTB1 ORC3 ORC3 ORC1 ORC1 MCM3 MCM3 UY3_08513 UY3_08513 HMOX1 HMOX1 UY3_08094 UY3_08094 MCM2 MCM2 CDK2 CDK2 UY3_07924 UY3_07924 UY3_10732 UY3_10732 UY3_06881 UY3_06881 RPA1 RPA1 UY3_02439 UY3_02439 UY3_03974 UY3_03974 UY3_06189 UY3_06189 UY3_02503 UY3_02503 UY3_10152 UY3_10152 UY3_06093 UY3_06093 UY3_01679 UY3_01679 RAD9A RAD9A CDC6 CDC6 UY3_03022 UY3_03022 UY3_06517 UY3_06517
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDK3Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (308 aa)
UY3_17734Replication factor C subunit 4. (328 aa)
RFC3Replication factor C subunit 3. (327 aa)
DBF4Protein DBF4 like protein A. (488 aa)
MCM8DNA replication licensing factor MCM8; Belongs to the MCM family. (905 aa)
UY3_10496RCC1 and BTB domain-containing protein 2. (534 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (537 aa)
ORC3Origin recognition complex subunit 3. (655 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (839 aa)
MCM3DNA helicase; Belongs to the MCM family. (795 aa)
UY3_08513Checkpoint protein; Belongs to the HUS1 family. (256 aa)
HMOX1DNA helicase; Belongs to the MCM family. (932 aa)
UY3_08094DNA helicase; Belongs to the MCM family. (730 aa)
MCM2DNA helicase; Belongs to the MCM family. (893 aa)
CDK2Cyclin-dependent kinase 2. (279 aa)
UY3_07924Claspin. (1263 aa)
UY3_10732Origin recognition complex subunit 5. (434 aa)
UY3_06881Origin recognition complex subunit 6. (160 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (574 aa)
UY3_02439Cell division control protein 45 like protein. (372 aa)
UY3_03974Protein MCM10 like protein. (977 aa)
UY3_06189Cell division cycle 7-related protein kinase; Belongs to the protein kinase superfamily. (481 aa)
UY3_02503Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (1896 aa)
UY3_10152Replication protein A 14 kDa subunit. (180 aa)
UY3_06093DNA helicase; Belongs to the MCM family. (770 aa)
UY3_01679Replication factor C subunit 2. (286 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (393 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (557 aa)
UY3_03022ATR-interacting protein. (1023 aa)
UY3_06517Cell cycle checkpoint protein RAD17. (507 aa)
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.