STRINGSTRING
KXD1 KXD1 CDK3 CDK3 POLH POLH UY3_18466 UY3_18466 POLE POLE UY3_17734 UY3_17734 RFC3 RFC3 UY3_16896 UY3_16896 BABAM1 BABAM1 UY3_16894 UY3_16894 CCNA1 CCNA1 UY3_16742 UY3_16742 UBB UBB UY3_16261 UY3_16261 PIAS4 PIAS4 UY3_18660 UY3_18660 UY3_18503 UY3_18503 RNF169 RNF169 UY3_18438 UY3_18438 UY3_13333 UY3_13333 FAM175A FAM175A UY3_18168 UY3_18168 DNAAF2 DNAAF2 UY3_12510 UY3_12510 UY3_12361 UY3_12361 UY3_14023 UY3_14023 UY3_13463 UY3_13463 UY3_00018 UY3_00018 RFC1 RFC1 UY3_11466 UY3_11466 UY3_11445 UY3_11445 POLK POLK UY3_11290 UY3_11290 RECQL4 RECQL4 UY3_11022 UY3_11022 UY3_08577 UY3_08577 UY3_09899 UY3_09899 RAD50 RAD50 UY3_10496 UY3_10496 UY3_11862 UY3_11862 BARD1 BARD1 RCBTB1 RCBTB1 UY3_18879 UY3_18879 UY3_17553 UY3_17553 UY3_08513 UY3_08513 UY3_12831 UY3_12831 UBE2N UBE2N CDK2 CDK2 UY3_11449 UY3_11449 UY3_06099 UY3_06099 POLD3 POLD3 PALB2 PALB2 TOP3A TOP3A UY3_10830 UY3_10830 UY3_06933 UY3_06933 UY3_04406 UY3_04406 RPA1 RPA1 PPP4R2 PPP4R2 UY3_04215 UY3_04215 UY3_14025 UY3_14025 XRCC3 XRCC3 UY3_03050 UY3_03050 PARP3 PARP3 UY3_12709 UY3_12709 UY3_05023 UY3_05023 RMI1 RMI1 RHNO1 RHNO1 TDRD3 TDRD3 EXD2 EXD2 UY3_02272 UY3_02272 TIPIN TIPIN UY3_01589 UY3_01589 UY3_06783 UY3_06783 UY3_00589 UY3_00589 UY3_10371 UY3_10371 UY3_02503 UY3_02503 UY3_10152 UY3_10152 EME1 EME1 SPIDR SPIDR UY3_00702 UY3_00702 NBN NBN UY3_01679 UY3_01679 ANKRD12 ANKRD12 RAD9A RAD9A UY3_00703 UY3_00703 UY3_07757 UY3_07757 BRCC3 BRCC3 UY3_03052 UY3_03052 UY3_03022 UY3_03022 UY3_06813 UY3_06813 UY3_02551 UY3_02551 ANKRD11 ANKRD11 UY3_06517 UY3_06517 DNA2 DNA2 UBE2V2 UBE2V2 RAD51B RAD51B UY3_00701 UY3_00701 PWWP2A PWWP2A MUS81 MUS81 UY3_03389 UY3_03389 UY3_03051 UY3_03051 UY3_01764 UY3_01764 XRCC1 XRCC1 MSGN1 MSGN1 UY3_00049 UY3_00049
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KXD1UPF0459 protein C19orf50 like protein. (388 aa)
CDK3Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (308 aa)
POLHDNA polymerase eta. (637 aa)
UY3_18466Poly [ADP-ribose] polymerase. (659 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2217 aa)
UY3_17734Replication factor C subunit 4. (328 aa)
RFC3Replication factor C subunit 3. (327 aa)
UY3_16896Histone H2B; Belongs to the histone H2B family. (126 aa)
BABAM1BRISC and BRCA1-A complex member 1. (325 aa)
UY3_16894Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (366 aa)
UY3_16742DNA excision repair protein ERCC-1. (208 aa)
UBBPolyubiquitin-C. (154 aa)
UY3_16261DNA polymerase delta subunit 4. (128 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (483 aa)
UY3_18660Poly [ADP-ribose] polymerase. (686 aa)
UY3_18503Serine/threonine-protein phosphatase 4 catalytic subunit B. (464 aa)
RNF169Uncharacterized protein. (638 aa)
UY3_18438BRCA1-A complex subunit BRE. (338 aa)
UY3_13333Replication factor C subunit 1. (221 aa)
FAM175ABRCA1-A complex subunit Abraxas. (235 aa)
UY3_18168Histone H2B; Belongs to the histone H2B family. (121 aa)
DNAAF2DNA polymerase epsilon subunit 2. (745 aa)
UY3_12510Histone H2B 8; Belongs to the histone H2B family. (121 aa)
UY3_12361Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (236 aa)
UY3_14023DNA repair protein RAD51 like protein 4. (323 aa)
UY3_13463Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
UY3_00018Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
RFC1Replication factor C subunit 1. (1038 aa)
UY3_11466DNA polymerase epsilon subunit 3. (147 aa)
UY3_11445Ankyrin repeat domain-containing protein 31. (1388 aa)
POLKDNA polymerase kappa. (803 aa)
UY3_11290DNA topoisomerase 2-binding protein 1-A. (1438 aa)
RECQL4ATP-dependent DNA helicase Q4. (1235 aa)
UY3_11022Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
UY3_08577Histone H2B; Belongs to the histone H2B family. (126 aa)
UY3_09899Werner syndrome ATP-dependent helicase. (1551 aa)
RAD50DNA repair protein RAD50. (1312 aa)
UY3_10496RCC1 and BTB domain-containing protein 2. (534 aa)
UY3_11862Protein timeless like protein. (1076 aa)
BARD1BRCA1-associated RING domain protein 1. (831 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (537 aa)
UY3_18879NAD-dependent deacetylase sirtuin-6. (366 aa)
UY3_17553DNA repair protein RAD52 like protein. (359 aa)
UY3_08513Checkpoint protein; Belongs to the HUS1 family. (256 aa)
UY3_12831Breast cancer type 2 susceptibility protein. (3332 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
CDK2Cyclin-dependent kinase 2. (279 aa)
UY3_11449DNA polymerase kappa. (132 aa)
UY3_06099DUF4502 domain-containing protein. (194 aa)
POLD3DNA polymerase delta subunit 3. (528 aa)
PALB2Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (2239 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (906 aa)
UY3_10830Flap endonuclease 1. (381 aa)
UY3_06933Serine-protein kinase ATM; Belongs to the PI3/PI4-kinase family. (2408 aa)
UY3_04406DNA endonuclease RBBP8. (855 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (574 aa)
PPP4R2Serine/threonine-protein phosphatase 4 regulatory subunit 2. (319 aa)
UY3_04215Cyclin-A2; Belongs to the cyclin family. (293 aa)
UY3_14025DNA ligase. (997 aa)
XRCC3DNA repair protein XRCC3. (268 aa)
UY3_03050Histone H2B.3; Belongs to the histone H2B family. (141 aa)
PARP3Poly [ADP-ribose] polymerase. (534 aa)
UY3_12709Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
UY3_05023DNA repair protein RAD51 like protein 3. (253 aa)
RMI1RecQ-mediated genome instability protein 1. (622 aa)
RHNO1Uncharacterized protein. (278 aa)
TDRD3Tudor domain-containing protein 3. (632 aa)
EXD2Exonuclease 3'-5' domain-containing protein 2. (657 aa)
UY3_02272Breast cancer type 1 susceptibility protein like protein. (1317 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (276 aa)
UY3_01589Ankyrin repeat domain-containing protein 32. (689 aa)
UY3_06783Bloom syndrome protein like protein. (1235 aa)
UY3_00589Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
UY3_10371ATP-dependent DNA helicase Q4. (163 aa)
UY3_02503Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (1896 aa)
UY3_10152Replication protein A 14 kDa subunit. (180 aa)
EME1Crossover junction endonuclease EME1. (597 aa)
SPIDRDUF4502 domain-containing protein. (191 aa)
UY3_00702Histone H2B.3. (146 aa)
NBNNibrin. (1008 aa)
UY3_01679Replication factor C subunit 2. (286 aa)
ANKRD12Ankyrin repeat domain-containing protein 12. (2043 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (393 aa)
UY3_00703Histone H2B 1.2. (141 aa)
UY3_07757Cell division cycle-associated protein 7. (505 aa)
BRCC3Lys-63-specific deubiquitinase BRCC36. (340 aa)
UY3_03052Histone H2B 1/2. (129 aa)
UY3_03022ATR-interacting protein. (1023 aa)
UY3_06813Tumor suppressor p53-binding protein 1. (1746 aa)
UY3_02551DNA polymerase delta catalytic subunit. (320 aa)
ANKRD11Ankyrin repeat domain-containing protein 11. (2609 aa)
UY3_06517Cell cycle checkpoint protein RAD17. (507 aa)
DNA2DNA2-like helicase. (1022 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (140 aa)
RAD51BDNA repair protein RAD51 like protein 2. (268 aa)
UY3_00701Histone H2B 1/2. (141 aa)
PWWP2APWWP domain-containing protein 2A. (782 aa)
MUS81Crossover junction endonuclease MUS81. (597 aa)
UY3_03389Putative histone-lysine N-methyltransferase NSD2. (1367 aa)
UY3_03051Histone H2B.1/H2B.2; Belongs to the histone H2B family. (121 aa)
UY3_01764DNA repair protein RAD51 like protein 2. (108 aa)
XRCC1DNA repair protein XRCC1. (509 aa)
MSGN1Flap endonuclease GEN like protein 1. (483 aa)
UY3_00049Histone H2B type 1-P; Belongs to the histone H2B family. (144 aa)
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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