STRINGSTRING
UY3_13506 UY3_13506 UY3_00049 UY3_00049 UY3_00887 UY3_00887 UY3_02574 UY3_02574 UY3_03051 UY3_03051 UY3_00701 UY3_00701 RPL35A RPL35A ANAPC5 ANAPC5 ANAPC7 ANAPC7 DNA2 DNA2 UY3_06251 UY3_06251 UY3_02551 UY3_02551 PSMC1 PSMC1 UY3_03052 UY3_03052 PSMB2 PSMB2 UY3_08545 UY3_08545 UY3_00703 UY3_00703 CDC6 CDC6 KPNB1 KPNB1 UY3_01679 UY3_01679 UY3_09597 UY3_09597 UY3_01880 UY3_01880 UY3_00702 UY3_00702 UY3_06093 UY3_06093 UY3_10152 UY3_10152 UY3_06189 UY3_06189 UY3_00589 UY3_00589 GINS4 GINS4 UY3_01330 UY3_01330 UY3_03974 UY3_03974 PSMC3 PSMC3 UY3_04151 UY3_04151 PSMA1 PSMA1 UY3_02439 UY3_02439 UY3_02593 UY3_02593 UY3_12709 UY3_12709 PSMD6 PSMD6 PSMD1 PSMD1 UY3_03050 UY3_03050 UY3_05428 UY3_05428 GINS1 GINS1 PSMD14 PSMD14 UY3_04215 UY3_04215 RPA1 RPA1 UY3_06599 UY3_06599 UY3_06881 UY3_06881 UY3_10732 UY3_10732 CDC16 CDC16 UY3_10830 UY3_10830 PSMD10 PSMD10 UY3_15079 UY3_15079 GMNN GMNN POLD3 POLD3 UY3_08186 UY3_08186 CUL1 CUL1 CDK2 CDK2 PSME2 PSME2 MCM2 MCM2 PSMA7 PSMA7 UY3_08094 UY3_08094 HMOX1 HMOX1 PSMB7 PSMB7 POLA1 POLA1 UY3_10082 UY3_10082 UY3_10047 UY3_10047 KPNA1 KPNA1 ANAPC16 ANAPC16 MCM3 MCM3 UY3_09133 UY3_09133 PSMB3 PSMB3 UY3_09022 UY3_09022 UY3_10735 UY3_10735 UY3_14202 UY3_14202 PSMD13 PSMD13 ORC1 ORC1 ORC3 ORC3 RCBTB1 RCBTB1 UY3_09515 UY3_09515 UY3_10496 UY3_10496 PSMC6 PSMC6 UY3_08577 UY3_08577 UY3_11022 UY3_11022 UY3_11466 UY3_11466 RFC1 RFC1 FZR1 FZR1 UY3_00018 UY3_00018 UY3_13463 UY3_13463 UY3_11075 UY3_11075 UY3_12361 UY3_12361 UY3_12510 UY3_12510 DNAAF2 DNAAF2 CDC23 CDC23 UY3_18168 UY3_18168 UY3_13333 UY3_13333 MCM8 MCM8 UY3_18893 UY3_18893 DBF4 DBF4 UY3_16261 UY3_16261 CDC26 CDC26 CCNE2 CCNE2 UBB UBB MCM9 MCM9 ANAPC2 ANAPC2 UY3_14946 UY3_14946 UY3_14273 UY3_14273 UY3_14452 UY3_14452 ANAPC10 ANAPC10 UY3_17223 UY3_17223 PIP5K1A PIP5K1A CCNA1 CCNA1 PSMD2 PSMD2 UY3_16894 UY3_16894 UY3_16615 UY3_16615 UY3_16638 UY3_16638 UY3_16896 UY3_16896 RFC3 RFC3 UY3_16912 UY3_16912 UY3_17734 UY3_17734 PSMB1 PSMB1 POLE POLE CDK3 CDK3 PSMC5 PSMC5 KXD1 KXD1 UY3_19055 UY3_19055
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UY3_13506DNA primase; Belongs to the eukaryotic-type primase small subunit family. (508 aa)
UY3_00049Histone H2B type 1-P; Belongs to the histone H2B family. (144 aa)
UY3_00887RING-box protein 1. (249 aa)
UY3_0257426S proteasome non-ATPase regulatory subunit 12. (371 aa)
UY3_03051Histone H2B.1/H2B.2; Belongs to the histone H2B family. (121 aa)
UY3_00701Histone H2B 1/2. (141 aa)
RPL35A26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (970 aa)
ANAPC5Anaphase-promoting complex subunit 5. (685 aa)
ANAPC7Anaphase-promoting complex subunit 7. (841 aa)
DNA2DNA2-like helicase. (1022 aa)
UY3_06251Anaphase-promoting complex subunit 1. (1807 aa)
UY3_02551DNA polymerase delta catalytic subunit. (320 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (367 aa)
UY3_03052Histone H2B 1/2. (129 aa)
PSMB2Proteasome subunit beta. (164 aa)
UY3_08545Importin subunit alpha-1. (672 aa)
UY3_00703Histone H2B 1.2. (141 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (557 aa)
KPNB1Importin subunit beta-1. (843 aa)
UY3_01679Replication factor C subunit 2. (286 aa)
UY3_09597Proteasome inhibitor PI31 subunit. (207 aa)
UY3_01880Proteasome subunit beta type-9. (105 aa)
UY3_00702Histone H2B.3. (146 aa)
UY3_06093DNA helicase; Belongs to the MCM family. (770 aa)
UY3_10152Replication protein A 14 kDa subunit. (180 aa)
UY3_06189Cell division cycle 7-related protein kinase; Belongs to the protein kinase superfamily. (481 aa)
UY3_00589Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (243 aa)
UY3_0133026S proteasome non-ATPase regulatory subunit 11. (442 aa)
UY3_03974Protein MCM10 like protein. (977 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (385 aa)
UY3_04151Importin subunit alpha; Belongs to the importin alpha family. (530 aa)
PSMA1Proteasome endopeptidase complex. (266 aa)
UY3_02439Cell division control protein 45 like protein. (372 aa)
UY3_02593ATPase family AAA domain-containing protein 5. (1597 aa)
UY3_12709Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (326 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1. (283 aa)
UY3_03050Histone H2B.3; Belongs to the histone H2B family. (141 aa)
UY3_05428Anaphase-promoting complex subunit 4. (725 aa)
GINS1DNA replication complex GINS protein PSF1. (216 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (294 aa)
UY3_04215Cyclin-A2; Belongs to the cyclin family. (293 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (574 aa)
UY3_06599DNA replication factor Cdt1. (480 aa)
UY3_06881Origin recognition complex subunit 6. (160 aa)
UY3_10732Origin recognition complex subunit 5. (434 aa)
CDC16Cell division cycle protein 16 like protein. (692 aa)
UY3_10830Flap endonuclease 1. (381 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
UY3_15079Proteasome subunit alpha type. (245 aa)
GMNNGeminin. (258 aa)
POLD3DNA polymerase delta subunit 3. (528 aa)
UY3_0818626S proteasome non-ATPase regulatory subunit 5. (415 aa)
CUL1Cullin-1; Belongs to the cullin family. (412 aa)
CDK2Cyclin-dependent kinase 2. (279 aa)
PSME2Proteasome activator complex subunit 2. (199 aa)
MCM2DNA helicase; Belongs to the MCM family. (893 aa)
PSMA7Proteasome endopeptidase complex. (287 aa)
UY3_08094DNA helicase; Belongs to the MCM family. (730 aa)
HMOX1DNA helicase; Belongs to the MCM family. (932 aa)
PSMB7Proteasome subunit beta type-7. (152 aa)
POLA1DNA polymerase alpha catalytic subunit. (957 aa)
UY3_10082Histone H2A; Belongs to the histone H2A family. (127 aa)
UY3_10047Transmembrane 7 superfamily member 3. (564 aa)
KPNA1Importin subunit alpha-1. (221 aa)
ANAPC16Anaphase-promoting complex subunit 16. (110 aa)
MCM3DNA helicase; Belongs to the MCM family. (795 aa)
UY3_0913326S proteasome non-ATPase regulatory subunit 3. (909 aa)
PSMB3Proteasome subunit beta. (227 aa)
UY3_09022Cell division cycle protein 27 like protein. (985 aa)
UY3_1073526S protease regulatory subunit 7; Belongs to the AAA ATPase family. (386 aa)
UY3_1420226S proteasome non-ATPase regulatory subunit 8. (231 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (839 aa)
ORC3Origin recognition complex subunit 3. (655 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (537 aa)
UY3_0951526S proteasome non-ATPase regulatory subunit 7. (459 aa)
UY3_10496RCC1 and BTB domain-containing protein 2. (534 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (308 aa)
UY3_08577Histone H2B; Belongs to the histone H2B family. (126 aa)
UY3_11022Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
UY3_11466DNA polymerase epsilon subunit 3. (147 aa)
RFC1Replication factor C subunit 1. (1038 aa)
FZR1Fizzy-related protein like protein. (637 aa)
UY3_00018Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
UY3_13463Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
UY3_11075S-phase kinase-associated protein 2. (229 aa)
UY3_12361Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (236 aa)
UY3_12510Histone H2B 8; Belongs to the histone H2B family. (121 aa)
DNAAF2DNA polymerase epsilon subunit 2. (745 aa)
CDC23Cell division cycle protein 23 like protein. (589 aa)
UY3_18168Histone H2B; Belongs to the histone H2B family. (121 aa)
UY3_13333Replication factor C subunit 1. (221 aa)
MCM8DNA replication licensing factor MCM8; Belongs to the MCM family. (905 aa)
UY3_18893DNA ligase 1; Belongs to the ATP-dependent DNA ligase family. (1122 aa)
DBF4Protein DBF4 like protein A. (488 aa)
UY3_16261DNA polymerase delta subunit 4. (128 aa)
CDC26Anaphase-promoting complex subunit CDC26. (83 aa)
CCNE2G1/S-specific cyclin-E2. (334 aa)
UBBPolyubiquitin-C. (154 aa)
MCM9DNA replication licensing factor MCM9; Belongs to the MCM family. (879 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (787 aa)
UY3_14946Proteasome subunit beta; Belongs to the peptidase T1B family. (227 aa)
UY3_14273Transmembrane 4 L6 family member 1. (152 aa)
UY3_14452Importin subunit alpha; Belongs to the importin alpha family. (494 aa)
ANAPC10Anaphase-promoting complex subunit 10. (157 aa)
UY3_17223DNA polymerase alpha catalytic subunit. (409 aa)
PIP5K1A26S proteasome non-ATPase regulatory subunit 4. (486 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (366 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (859 aa)
UY3_16894Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (101 aa)
UY3_1661526S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (386 aa)
UY3_16638Histone H2A; Belongs to the histone H2A family. (124 aa)
UY3_16896Histone H2B; Belongs to the histone H2B family. (126 aa)
RFC3Replication factor C subunit 3. (327 aa)
UY3_16912Anaphase-promoting complex subunit 10. (116 aa)
UY3_17734Replication factor C subunit 4. (328 aa)
PSMB1Proteasome subunit beta. (203 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2217 aa)
CDK3Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (308 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (357 aa)
KXD1UPF0459 protein C19orf50 like protein. (388 aa)
UY3_19055Proteasome activator complex subunit 4. (1888 aa)
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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