STRINGSTRING
TEAD1 TEAD1 CCNA1 CCNA1 CCNE2 CCNE2 EIF3G EIF3G UY3_12361 UY3_12361 BMP6 BMP6 UHRF1 UHRF1 DNMT3B DNMT3B GADD45G GADD45G CCND1 CCND1 TEAD3 TEAD3 CDC6 CDC6 CDK7 CDK7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TEAD1Transcriptional enhancer factor TEF-1. (59 aa)
CCNA1Cyclin-A1; Belongs to the cyclin family. (366 aa)
CCNE2G1/S-specific cyclin-E2. (334 aa)
EIF3GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (1889 aa)
UY3_12361Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (236 aa)
BMP6Bone morphogenetic protein 6. (320 aa)
UHRF1E3 ubiquitin-protein ligase UHRF1. (793 aa)
DNMT3BDNA (Cytosine-5)-methyltransferase 3B; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (798 aa)
GADD45GGrowth arrest and DNA damage-inducible protein GADD45 gamma. (162 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (292 aa)
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (495 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (557 aa)
CDK7Cyclin-dependent kinase 7. (406 aa)
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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