STRINGSTRING
dnaX dnaX SFB45306.1 SFB45306.1 ligA ligA SFB45160.1 SFB45160.1 SFA75399.1 SFA75399.1 SFA79645.1 SFA79645.1 SFA92296.1 SFA92296.1 mutS2 mutS2 polC polC xseB xseB xseA xseA SFB43821.1 SFB43821.1 addA addA SFB36649.1 SFB36649.1 SFB34980.1 SFB34980.1 SFB32487.1 SFB32487.1 SFB32213.1 SFB32213.1 SFB29939.1 SFB29939.1 SFB23113.1 SFB23113.1 SFB23063.1 SFB23063.1 SFB22487.1 SFB22487.1 SFB17478.1 SFB17478.1 SFB16922.1 SFB16922.1 SFB16873.1 SFB16873.1 prsA prsA SFB08686.1 SFB08686.1 SFB05759.1 SFB05759.1 SFB05690.1 SFB05690.1 SFA96138.1 SFA96138.1 SFA96121.1 SFA96121.1 SFA92654.1 SFA92654.1 SFA71911.1 SFA71911.1 SFA69495.1 SFA69495.1 lexA lexA mutL mutL mutS mutS SFA76923.1 SFA76923.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaXDNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (547 aa)
SFB45306.1Peptidyl-prolyl cis-trans isomerase C. (248 aa)
ligADNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (664 aa)
SFB45160.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (752 aa)
SFA75399.1DNA polymerase III, delta subunit. (340 aa)
SFA79645.1Single-strand DNA-binding protein. (110 aa)
SFA92296.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (762 aa)
mutS2DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (788 aa)
polCDNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1444 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (72 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (400 aa)
SFB43821.1DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] (367 aa)
addADNA helicase/exodeoxyribonuclease V, subunit A; ATP-dependent DNA helicase. (1251 aa)
SFB36649.1Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
SFB34980.1DNA polymerase-3 subunit delta'. (311 aa)
SFB32487.1MutS domain V; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (498 aa)
SFB32213.1Single-strand binding protein. (161 aa)
SFB29939.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (705 aa)
SFB23113.1Metallo-beta-lactamase family protein. (459 aa)
SFB23063.1Exonuclease RecJ. (584 aa)
SFB22487.1DNA polymerase-3 subunit epsilon. (205 aa)
SFB17478.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (861 aa)
SFB16922.1DNA adenine methylase (dam). (630 aa)
SFB16873.1DNA mismatch repair protein MutH. (216 aa)
prsAFoldase protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (333 aa)
SFB08686.1DNA polymerase-3 subunit alpha. (1206 aa)
SFB05759.1MutS domain V. (594 aa)
SFB05690.1SOS regulatory protein LexA; Belongs to the peptidase S24 family. (460 aa)
SFA96138.1Superfamily I DNA or RNA helicase. (654 aa)
SFA96121.1DNA adenine methylase. (269 aa)
SFA92654.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (667 aa)
SFA71911.1CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (164 aa)
SFA69495.1Single-stranded DNA-binding protein. (239 aa)
lexARepressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (203 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (641 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (889 aa)
SFA76923.1Hypothetical protein. (277 aa)
Your Current Organism:
Clostridium frigidicarnis
NCBI taxonomy Id: 84698
Other names: ATCC BAA-154, C. frigidicarnis, DSM 12271, strain SPL77A
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