(107 nodes) Inner ear development network (Chrysemys picta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC17A8	Solute carrier family 17 member 8. (404 aa)
	ENSCPBP00000006710	annotation not available (110 aa)
	S1PR2	Sphingosine 1-phosphate receptor 2. (357 aa)
	OTOP1	Otopetrin 1. (597 aa)
	CYTL1	Cytokine like 1. (133 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (501 aa)
	MYO3B	Myosin IIIB. (1259 aa)
	SOBP	Sine oculis binding protein homolog. (873 aa)
	SCRIB	Scribble planar cell polarity protein. (1512 aa)
	WHRN	Whirlin. (186 aa)
	ENSCPBP00000008262	annotation not available (605 aa)
	HPN	Hepsin. (411 aa)
	ENSCPBP00000009390	Forkhead box protein G1-like. (164 aa)
	C1QTNF5	C1q and tumor necrosis factor related protein 5. (246 aa)
	GRXCR2	Glutaredoxin and cysteine rich domain containing 2. (252 aa)
	TTC8	Tetratricopeptide repeat protein 8. (455 aa)
	ENSCPBP00000011221	annotation not available (74 aa)
	CXCL14	C-X-C motif chemokine ligand 14. (98 aa)
	TRIP11	Thyroid receptor-interacting protein 11. (1959 aa)
	PLS1	Plastin 1. (630 aa)
	TBX2	T-box protein 2. (677 aa)
	MKS1	Meckel syndrome type 1 protein. (565 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit. (463 aa)
	C1QB	Complement C1q subcomponent subunit B. (240 aa)
	KCNQ1	Potassium voltage-gated channel KQT-like subfamily member 1. (856 aa)
	ENSCPBP00000014160	annotation not available (306 aa)
	ADGRV1	Adhesion G protein-coupled receptor V1. (1363 aa)
	ENSCPBP00000014211	annotation not available (1170 aa)
	BMPER	BMP-binding endothelial regulator protein. (477 aa)
	TBX3	T-box protein 3. (721 aa)
	RPGRIP1L	Protein fantom. (1273 aa)
	SLC44A4	Solute carrier family 44 (choline transporter-like protein), member 2/4/5. (557 aa)
	SLITRK6	SLIT and NTRK like family member 6. (840 aa)
	HESX1	Homeobox protein expressed in ES cells 1. (197 aa)
	DLL1	Delta like canonical Notch ligand 1. (728 aa)
	ENSCPBP00000017852	annotation not available (1448 aa)
	USH2A	Usherin. (3393 aa)
	KCNK2	Potassium two pore domain channel subfamily K member 2. (410 aa)
	OTX1	Orthodenticle homeobox 1. (334 aa)
	WDPCP	WD repeat-containing and planar cell polarity effector protein. (719 aa)
	ATOH1	Atonal bHLH transcription factor 1. (218 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (834 aa)
	ENSCPBP00000019438	annotation not available (115 aa)
	IFT20	Intraflagellar transport protein 20. (132 aa)
	LRIG3	Leucine rich repeats and immunoglobulin like domains 3. (1115 aa)
	MCM2	Minichromosome maintenance complex component 2. (826 aa)
	SLC26A5	Solute carrier family 26, member 5. (748 aa)
	REST	RE1 silencing transcription factor. (892 aa)
	CCM2	CCM2 scaffolding protein. (467 aa)
	MYO3A	Myosin IIIA. (1688 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1104 aa)
	NAGLU	N-acetyl-alpha-glucosaminidase. (752 aa)
	USH1C	USH1 protein network component harmonin. (455 aa)
	AHI1	Abelson helper integration site 1. (1251 aa)
	DLL3	Delta like canonical Notch ligand 3. (545 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3. (549 aa)
	GATA3	GATA binding protein 3. (444 aa)
	FZD3	Frizzled class receptor 3. (666 aa)
	WNT1	Wnt family member 1. (319 aa)
	JAG2	Jagged 2. (1240 aa)
	ENSCPBP00000028946	annotation not available (451 aa)
	IFT88	Intraflagellar transport protein 88. (800 aa)
	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta. (502 aa)
	ENSCPBP00000031245	Pejvakin-like. (216 aa)
	MPV17	MPV17, mitochondrial inner membrane protein. (218 aa)
	LRRC1	Leucine rich repeat containing 1. (772 aa)
	CLDN7	Claudin 7. (212 aa)
	GSDME	DFNA5, deafness associated tumor suppressor. (571 aa)
	HOXA13	Homeobox protein HoxA/C/D13. (290 aa)
	SLC4A7	Solute carrier family 4 (sodium bicarbonate cotransporter), member 7. (1256 aa)
	GBX2	Gastrulation brain homeobox 2. (344 aa)
	JAG1	Jagged 1. (1213 aa)
	NBL1	Neuroblastoma suppressor of tumorigenicity 1. (196 aa)
	MYO6	Myosin VI. (962 aa)
	DLX5	Distal-less homeobox 5. (335 aa)
	DLX6	Homeobox protein DLX1/4/6. (175 aa)
	FGF2	Fibroblast growth factor 2. (155 aa)
	GLI3	GLI family zinc finger 3. (1575 aa)
	FOXG1	Forkhead box protein G. (466 aa)
	PHOX2B	Paired mesoderm homeobox protein 2. (287 aa)
	GRXCR1	Glutaredoxin domain-containing cysteine-rich protein 1. (293 aa)
	CTHRC1	Collagen triple helix repeat containing 1. (239 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (313 aa)
	LRIG1	Leucine rich repeats and immunoglobulin like domains 1. (1091 aa)
	TTC39C	Tetratricopeptide repeat domain 39C. (580 aa)
	FREM3	FRAS1-related extracellular matrix protein 3. (3151 aa)
	USH1G	USH1 protein network component sans. (469 aa)
	CECR2	Cat eye syndrome chromosome region, candidate 2. (1496 aa)
	PTPRQ	Protein tyrosine phosphatase, receptor type Q. (2321 aa)
	ENSCPBP00000000754	Potassium voltage-gated channel KQT-like subfamily member 1. (454 aa)
	TPRN	Taperin. (639 aa)
	ROR1	Receptor tyrosine kinase like orphan receptor 1. (933 aa)
	ENSCPBP00000001875	annotation not available (225 aa)
	MAPKAPK2	Mitogen-activated protein kinase-activated protein kinase 2. (398 aa)
	TSHR	Thyroid stimulating hormone receptor. (749 aa)
	ATG4B	Autophagy related 4B cysteine peptidase. (436 aa)
	FREM2	FRAS1-related extracelluar matrix protein 1/2. (3163 aa)
	DFNB59	Deafness, autosomal recessive 59. (188 aa)
	ENSCPBP00000003928	Disintegrin and metalloproteinase domain-containing protein 10. (285 aa)
	PTK7	Protein tyrosine kinase 7 (inactive). (1091 aa)
	ENSCPBP00000004255	annotation not available (221 aa)
	PDZD7	PDZ domain-containing protein 7. (606 aa)
	FGF8	Fibroblast growth factor 8. (214 aa)
	ENSCPBP00000005096	Transmembrane O-methyltransferase. (259 aa)
	ATG5	Autophagy-related protein 5. (333 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1218 aa)
	ENSCPBP00000005567	Homeobox protein DLL-1-like. (68 aa)

Your Current Organism:

Chrysemys picta

NCBI taxonomy Id: 8478
Other names: C. picta bellii, Chrysemys picta bellii, Chrysemys picta subsp. bellii, western painted turtle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	DLL1	ENSCPBP00000007315	ENSCPBP00000016983	Disintegrin and metalloproteinase domain-containing protein 10.	Delta like canonical Notch ligand 1.	0.472
ADAM10	DLL3	ENSCPBP00000007315	ENSCPBP00000026637	Disintegrin and metalloproteinase domain-containing protein 10.	Delta like canonical Notch ligand 3.	0.472
ADAM10	ENSCPBP00000003928	ENSCPBP00000007315	ENSCPBP00000003928	Disintegrin and metalloproteinase domain-containing protein 10.	Disintegrin and metalloproteinase domain-containing protein 10.	0.947
ADGRV1	ENSCPBP00000014160	ENSCPBP00000014179	ENSCPBP00000014160	Adhesion G protein-coupled receptor V1.	annotation not available	0.918
ADGRV1	USH1C	ENSCPBP00000014179	ENSCPBP00000024677	Adhesion G protein-coupled receptor V1.	USH1 protein network component harmonin.	0.418
AHI1	IFT88	ENSCPBP00000024749	ENSCPBP00000029474	Abelson helper integration site 1.	Intraflagellar transport protein 88.	0.488
AHI1	MKS1	ENSCPBP00000024749	ENSCPBP00000013219	Abelson helper integration site 1.	Meckel syndrome type 1 protein.	0.850
AHI1	RPGRIP1L	ENSCPBP00000024749	ENSCPBP00000016547	Abelson helper integration site 1.	Protein fantom.	0.647
ATG4B	ATG5	ENSCPBP00000002713	ENSCPBP00000005191	Autophagy related 4B cysteine peptidase.	Autophagy-related protein 5.	0.611
ATG5	ATG4B	ENSCPBP00000005191	ENSCPBP00000002713	Autophagy-related protein 5.	Autophagy related 4B cysteine peptidase.	0.611
ATOH1	PHOX2B	ENSCPBP00000018051	ENSCPBP00000036928	Atonal bHLH transcription factor 1.	Paired mesoderm homeobox protein 2.	0.620
DFNB59	ENSCPBP00000031245	ENSCPBP00000003764	ENSCPBP00000031245	Deafness, autosomal recessive 59.	Pejvakin-like.	0.928
DLL1	ADAM10	ENSCPBP00000016983	ENSCPBP00000007315	Delta like canonical Notch ligand 1.	Disintegrin and metalloproteinase domain-containing protein 10.	0.472
DLL1	DLL3	ENSCPBP00000016983	ENSCPBP00000026637	Delta like canonical Notch ligand 1.	Delta like canonical Notch ligand 3.	0.901
DLL1	ENSCPBP00000003928	ENSCPBP00000016983	ENSCPBP00000003928	Delta like canonical Notch ligand 1.	Disintegrin and metalloproteinase domain-containing protein 10.	0.472
DLL1	JAG1	ENSCPBP00000016983	ENSCPBP00000033341	Delta like canonical Notch ligand 1.	Jagged 1.	0.474
DLL3	ADAM10	ENSCPBP00000026637	ENSCPBP00000007315	Delta like canonical Notch ligand 3.	Disintegrin and metalloproteinase domain-containing protein 10.	0.472
DLL3	DLL1	ENSCPBP00000026637	ENSCPBP00000016983	Delta like canonical Notch ligand 3.	Delta like canonical Notch ligand 1.	0.901
DLL3	ENSCPBP00000003928	ENSCPBP00000026637	ENSCPBP00000003928	Delta like canonical Notch ligand 3.	Disintegrin and metalloproteinase domain-containing protein 10.	0.472
DLL3	JAG1	ENSCPBP00000026637	ENSCPBP00000033341	Delta like canonical Notch ligand 3.	Jagged 1.	0.474