STRINGSTRING
GLB1 GLB1 CERS6 CERS6 PECR PECR SGPP1 SGPP1 ARV1 ARV1 ACER3 ACER3 CERS2 CERS2 SPTLC3 SPTLC3 NCEH1 NCEH1 ARSI ARSI SPTLC1 SPTLC1 CUNH9orf3 CUNH9orf3 APOV1 APOV1 PLPP7 PLPP7 SPHK2 SPHK2 SPTLC3-2 SPTLC3-2 ISM1 ISM1 HGSNAT HGSNAT SGMS2 SGMS2 SUMF1 SUMF1 DEGS2 DEGS2 GPR182 GPR182 DNASE2 DNASE2 TTPA TTPA B4GALT6-2 B4GALT6-2 OSBPL3 OSBPL3 CERS5 CERS5 GBA2 GBA2 SAMD8 SAMD8 BMS1-2 BMS1-2 GALNS GALNS PAPLN PAPLN COL7A1 COL7A1 Y1Q_0022503 Y1Q_0022503 TEX2 TEX2 TEX2-2 TEX2-2 ARSG ARSG SPHK1 SPHK1 SMPD4 SMPD4 IDS IDS SMPD2 SMPD2 GBA GBA NAGLU NAGLU ORMDL1 ORMDL1 SGPP2 SGPP2 CERS4 CERS4 ORMDL2 ORMDL2 Y1Q_0000948 Y1Q_0000948 UGCG UGCG IDUA IDUA KDSR KDSR Y1Q_0020688 Y1Q_0020688 MIER1 MIER1 SPTSSA SPTSSA MPZ MPZ SGSH SGSH HIKESHI HIKESHI CERK CERK PLPP6 PLPP6 STS STS ACER1 ACER1 ARSD ARSD ARSD-2 ARSD-2 OSBPL2 OSBPL2 SGPL1 SGPL1 ASAH2 ASAH2 CERS1 CERS1 GLB1-2 GLB1-2 DEGS1 DEGS1 EDRF1 EDRF1 Y1Q_0011852 Y1Q_0011852 SMPD1 SMPD1 ARSA ARSA ASAH1 ASAH1 CLCN1 CLCN1 UGT8 UGT8 ARSJ ARSJ GNS GNS FABP3 FABP3 Y1Q_0001974 Y1Q_0001974 DECR1 DECR1 ARSB ARSB ARSK ARSK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLB1Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family. (569 aa)
CERS6Ceramide synthase 6. (411 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase. (303 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (262 aa)
ARV1Protein ARV1. (237 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
CERS2Ceramide synthase 2. (393 aa)
SPTLC3Serine palmitoyltransferase 3 isoform A. (571 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (408 aa)
ARSIArylsulfatase I. (573 aa)
SPTLC1Serine palmitoyltransferase 1. (470 aa)
CUNH9orf3Aminopeptidase O. (836 aa)
APOV1Apovitellenin-1. (137 aa)
PLPP7Putative lipid phosphate phosphatase PPAPDC3. (327 aa)
SPHK2Sphingosine kinase 2. (591 aa)
SPTLC3-2Aminotran_1_2 domain-containing protein. (550 aa)
ISM1Isthmin-1. (453 aa)
HGSNATHeparan-alpha-glucosaminide N-acetyltransferase isoform A. (627 aa)
SGMS2Phosphatidylcholine:ceramide cholinephosphotransferase 2. (365 aa)
SUMF1Sulfatase-modifying factor 1. (351 aa)
DEGS2Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2. (322 aa)
GPR182G-protein coupled receptor 182; Belongs to the G-protein coupled receptor 1 family. (364 aa)
DNASE2Deoxyribonuclease-2-beta. (383 aa)
TTPAAlpha-tocopherol transfer protein isoform A. (293 aa)
B4GALT6-2Uncharacterized protein. (387 aa)
OSBPL3Oxysterol-binding protein; Belongs to the OSBP family. (851 aa)
CERS5Ceramide synthase 5. (384 aa)
GBA2Non-lysosomal glucosylceramidase. (597 aa)
SAMD8Sphingomyelin synthase-related protein 1. (232 aa)
BMS1-2Heparan-alpha-glucosaminide N-acetyltransferase-like. (496 aa)
GALNSN-acetylgalactosamine-6-sulfatase. (505 aa)
PAPLNPapilin isoform A. (1295 aa)
COL7A1Collagen alpha-1(VII) chain isoform C. (1626 aa)
Y1Q_0022503Steryl-sulfatase-like. (187 aa)
TEX2Testis-expressed sequence 2 protein. (1027 aa)
TEX2-2SMP-LTD domain-containing protein. (1150 aa)
ARSGArylsulfatase G isoform A. (544 aa)
SPHK1Sphingosine kinase 1. (537 aa)
SMPD4Sphingomyelin phosphodiesterase 4 isoform A. (829 aa)
IDSIduronate 2-sulfatase. (545 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (409 aa)
GBAGlucosylceramidase. (779 aa)
NAGLUAlpha-N-acetylglucosaminidase. (620 aa)
ORMDL1ORM1-like protein; Negative regulator of sphingolipid synthesis. (163 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (325 aa)
CERS4Ceramide synthase 4. (435 aa)
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
Y1Q_0000948Uncharacterized protein. (96 aa)
UGCGCeramide glucosyltransferase. (394 aa)
IDUAAlpha-L-iduronidase. (549 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (333 aa)
Y1Q_0020688Glucosylceramidase. (347 aa)
MIER1Mesoderm induction early response protein 1. (493 aa)
SPTSSASerine palmitoyltransferase small subunit A. (68 aa)
MPZMyelin protein P0. (249 aa)
SGSHN-sulfoglucosamine sulfohydrolase. (415 aa)
HIKESHIProtein Hikeshi. (197 aa)
CERKCeramide kinase isoform B. (523 aa)
PLPP6Presqualene diphosphate phosphatase. (203 aa)
STSSteryl-sulfatase. (355 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (318 aa)
ARSDArylsulfatase D. (592 aa)
ARSD-2Uncharacterized protein. (1100 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (474 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (617 aa)
ASAH2Neutral ceramidase. (1169 aa)
CERS1Ceramide synthase 1. (265 aa)
GLB1-2Beta-galactosidase. (651 aa)
DEGS1Sphingolipid delta(4)-desaturase DES1. (293 aa)
EDRF1Erythroid differentiation-related factor 1 isoform A. (1229 aa)
Y1Q_0011852Sulfatase domain-containing protein. (72 aa)
SMPD1Sphingomyelin phosphodiesterase. (287 aa)
ARSAArylsulfatase A. (384 aa)
ASAH1Acid ceramidase; Belongs to the acid ceramidase family. (395 aa)
CLCN1Chloride channel protein 1 isoform E. (1017 aa)
UGT82-hydroxyacylsphingosine 1-beta-galactosyltransferase; Belongs to the UDP-glycosyltransferase family. (541 aa)
ARSJSulfatase domain-containing protein. (389 aa)
GNSN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (531 aa)
FABP3Fatty acid-binding protein, heart; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
Y1Q_0001974UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (501 aa)
DECR12,4-dienoyl-CoA reductase, mitochondrial. (336 aa)
ARSBArylsulfatase B. (379 aa)
ARSKArylsulfatase K isoform B. (441 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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