(33 nodes) Neurexins and neuroligins, and Carboxylesterase type B, active site network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Y1Q_0021036	Uncharacterized protein. (952 aa)
	NRXN3	Neurexin 3. (552 aa)
	Y1Q_0021039	Uncharacterized protein. (353 aa)
	NLGN4X	Neuroligin-4, X-linked isoform B. (533 aa)
	Y1Q_0010673	COesterase domain-containing protein. (237 aa)
	Y1Q_0000547	ANK_REP_REGION domain-containing protein. (435 aa)
	SHANK2-2	Uncharacterized protein. (1191 aa)
	Y1Q_0019411	COesterase domain-containing protein. (181 aa)
	NXPH1	Neurexophilin; May be signaling molecules that resemble neuropeptides. (288 aa)
	SHANK2	SH3 and multiple ankyrin repeat domains protein 2. (524 aa)
	Y1Q_0004715	Uncharacterized protein. (349 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains protein 3-like. (1242 aa)
	UBN1	Ubinuclein-1 isoform A. (1614 aa)
	Y1Q_0011093	Uncharacterized protein. (239 aa)
	Y1Q_0011095	LAM_G_DOMAIN domain-containing protein. (334 aa)
	NRXN2	Uncharacterized protein. (788 aa)
	NRXN2A-1	Neurexin 2a isoform A. (343 aa)
	Y1Q_0003447	Disks large 1 tumor suppressor protein-like. (80 aa)
	Y1Q_0003445	Uncharacterized protein. (169 aa)
	Y1Q_0007811	Liver carboxylesterase 2-like; Belongs to the type-B carboxylesterase/lipase family. (1247 aa)
	CES5A	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (557 aa)
	CES1	Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family. (836 aa)
	DLGAP1	Uncharacterized protein. (919 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains protein 1 isoform A. (1730 aa)
	DLGAP2-2	Uncharacterized protein. (864 aa)
	NLGN4X-2	COesterase domain-containing protein. (812 aa)
	DLGAP4	Disks large-associated protein 4. (968 aa)
	MDGA1	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 isoform B. (967 aa)
	NLGN3	COesterase domain-containing protein. (610 aa)
	DLG1	Disks large-like protein 1 isoform D; Belongs to the MAGUK family. (1703 aa)
	MDGA2	Uncharacterized protein. (975 aa)
	Y1Q_0000001	COesterase domain-containing protein. (130 aa)
	DLGAP2	Disks large-associated protein 2 isoform C. (889 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CES1	CES5A	A0A151N794	A0A151N730	Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.903
CES1	Y1Q_0007811	A0A151N794	A0A151N729	Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family.	Liver carboxylesterase 2-like; Belongs to the type-B carboxylesterase/lipase family.	0.906
CES5A	CES1	A0A151N730	A0A151N794	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Liver carboxylesterase 1; Belongs to the type-B carboxylesterase/lipase family.	0.903
CES5A	Y1Q_0007811	A0A151N730	A0A151N729	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Liver carboxylesterase 2-like; Belongs to the type-B carboxylesterase/lipase family.	0.902
DLG1	DLGAP1	A0A151P8D4	A0A151NEM5	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	Uncharacterized protein.	0.749
DLG1	DLGAP2	A0A151P8D4	A0A151PGZ4	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	Disks large-associated protein 2 isoform C.	0.509
DLG1	DLGAP2-2	A0A151P8D4	A0A151NLF3	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	Uncharacterized protein.	0.630
DLG1	DLGAP4	A0A151P8D4	A0A151NZK3	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	Disks large-associated protein 4.	0.462
DLG1	SHANK1	A0A151P8D4	A0A151NK00	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains protein 1 isoform A.	0.593
DLG1	SHANK2	A0A151P8D4	A0A151MRD3	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains protein 2.	0.579
DLG1	SHANK2-2	A0A151P8D4	A0A151MBL7	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	Uncharacterized protein.	0.482
DLG1	SHANK3	A0A151P8D4	A0A151MRQ5	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	SH3 and multiple ankyrin repeat domains protein 3-like.	0.579
DLG1	Y1Q_0000547	A0A151P8D4	A0A151MBG4	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	ANK_REP_REGION domain-containing protein.	0.558
DLGAP1	DLG1	A0A151NEM5	A0A151P8D4	Uncharacterized protein.	Disks large-like protein 1 isoform D; Belongs to the MAGUK family.	0.749
DLGAP1	DLGAP2	A0A151NEM5	A0A151PGZ4	Uncharacterized protein.	Disks large-associated protein 2 isoform C.	0.477
DLGAP1	SHANK1	A0A151NEM5	A0A151NK00	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains protein 1 isoform A.	0.904
DLGAP1	SHANK2	A0A151NEM5	A0A151MRD3	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains protein 2.	0.864
DLGAP1	SHANK2-2	A0A151NEM5	A0A151MBL7	Uncharacterized protein.	Uncharacterized protein.	0.878
DLGAP1	SHANK3	A0A151NEM5	A0A151MRQ5	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains protein 3-like.	0.864
DLGAP1	Y1Q_0000547	A0A151NEM5	A0A151MBG4	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.766