(27 nodes) Tight junction, and Positive regulation of vascular permeability network (Alligator mississippiensis)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	KRT6A	Keratin 6A; Belongs to the intermediate filament family. (588 aa)
	CGN	Cingulin isoform A. (1295 aa)
	TJP1	Tight junction protein ZO-1 isoform A; Belongs to the MAGUK family. (1182 aa)
	Y1Q_0001622	Uncharacterized protein. (71 aa)
	Y1Q_0001619	ZU5 domain-containing protein. (497 aa)
	PLEKHA7	Pleckstrin-like proteiny domain-containing family A member 7. (1222 aa)
	JAM2	Junctional adhesion molecule B. (298 aa)
	CLDN8	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
	CLDN11	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (251 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	F11R	Junctional adhesion molecule A. (310 aa)
	Y1Q_0000183	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (188 aa)
	CUNH1orf50	Uncharacterized protein. (300 aa)
	P3H1	Prolyl 3-hydroxylase 1. (710 aa)
	TJP2	Tight junction protein ZO-2 isoform B; Belongs to the MAGUK family. (1039 aa)
	CLDN2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
	JAM3	Junctional adhesion molecule C. (319 aa)
	CLDN10-1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (232 aa)
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)
	CLDN9	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (214 aa)
	CLDN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (214 aa)
	CLDN4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (181 aa)
	CLDN15L	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
	CLDN7	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	CLDN25	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
	CLDN6	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
	Y1Q_0005391	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (216 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CGN	CLDN2	A0A151M598	A0A151NN31	Cingulin isoform A.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.438
CGN	PLEKHA7	A0A151M598	A0A151MC46	Cingulin isoform A.	Pleckstrin-like proteiny domain-containing family A member 7.	0.479
CGN	TJP1	A0A151M598	A0A151M8F6	Cingulin isoform A.	Tight junction protein ZO-1 isoform A; Belongs to the MAGUK family.	0.685
CGN	TJP2	A0A151M598	A0A151NCK4	Cingulin isoform A.	Tight junction protein ZO-2 isoform B; Belongs to the MAGUK family.	0.800
CGN	Y1Q_0001619	A0A151M598	A0A151MA82	Cingulin isoform A.	ZU5 domain-containing protein.	0.706
CGN	Y1Q_0001622	A0A151M598	A0A151MA57	Cingulin isoform A.	Uncharacterized protein.	0.706
CLDN1	CLDN10-1	A0A151MM51	A0A151NRJ0	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.692
CLDN1	CLDN11	A0A151MM51	A0A151MGB5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.686
CLDN1	CLDN15L	A0A151MM51	A0A151NUJ6	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.679
CLDN1	CLDN2	A0A151MM51	A0A151NN31	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.711
CLDN1	CLDN25	A0A151MM51	A0A151P1U0	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
CLDN1	CLDN3	A0A151MM51	A0A151NTZ8	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.716
CLDN1	CLDN4	A0A151MM51	A0A151NU82	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.794
CLDN1	CLDN5	A0A151MM51	A0A151NRN4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.763
CLDN1	CLDN6	A0A151MM51	A0A151PDY9	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.759
CLDN1	CLDN7	A0A151MM51	A0A151NXV9	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
CLDN1	CLDN8	A0A151MM51	A0A151ME29	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.708
CLDN1	CLDN9	A0A151MM51	A0A151NTM2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.699
CLDN1	F11R	A0A151MM51	A0A151MPJ7	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Junctional adhesion molecule A.	0.613
CLDN1	JAM2	A0A151MM51	A0A151ME03	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Junctional adhesion molecule B.	0.576