STRINGSTRING
Y1Q_0007599 Y1Q_0007599 NR1H4 NR1H4 ESR2 ESR2 TBL1XR1 TBL1XR1 NR3C1 NR3C1 NR1H3 NR1H3 NRIP1 NRIP1 Y1Q_0005761 Y1Q_0005761 RXRA RXRA HNF4G HNF4G NCOA2 NCOA2 NR1D2 NR1D2 TBL1X TBL1X GPS2 GPS2 RXRB RXRB FKBP5 FKBP5 CREB1 CREB1 NR1D4A NR1D4A NCOR1 NCOR1 NR5A2 NR5A2 CREBBPA CREBBPA Y1Q_0024039 Y1Q_0024039 NR0B2 NR0B2 FOXA1 FOXA1 ESR1 ESR1 AR AR KMT2E KMT2E GATA3 GATA3 HDAC3 HDAC3 Y1Q_0018673 Y1Q_0018673 NCOA3 NCOA3 NCOA1 NCOA1 SP1 SP1 VDR VDR PPARAB PPARAB PGR-1 PGR-1 NR3C2 NR3C2 NR1D1 NR1D1 PPARG PPARG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Y1Q_0007599Uncharacterized protein. (420 aa)
NR1H4Bile acid receptor. (453 aa)
ESR2Estrogen receptor beta. (406 aa)
TBL1XR1F-box-like/WD repeat-containing protein TBL1XR1. (513 aa)
NR3C1Glucocorticoid receptor. (742 aa)
NR1H3Oxysterols receptor LXR-alpha. (408 aa)
NRIP1Nuclear receptor-interacting protein 1. (391 aa)
Y1Q_0005761Uncharacterized protein. (485 aa)
RXRARetinoic acid receptor RXR-alpha. (467 aa)
HNF4GUncharacterized protein. (445 aa)
NCOA2Nuclear receptor coactivator. (1457 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2 isoform B. (589 aa)
TBL1XUncharacterized protein. (525 aa)
GPS2Inner centromere protein. (286 aa)
RXRBUncharacterized protein. (449 aa)
FKBP5Peptidylprolyl isomerase. (457 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
NR1D4ANuclear receptor subfamily 1, group D, member 4a. (431 aa)
NCOR1Nuclear receptor corepressor 1 isoform B. (2411 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (539 aa)
CREBBPACREB-binding protein isoform A. (1756 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (266 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (285 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
ARAndrogen receptor. (634 aa)
KMT2EHistone-lysine N-methyltransferase 2E isoform A. (1230 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (379 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
Y1Q_0018673Uncharacterized protein. (2454 aa)
NCOA3Nuclear receptor coactivator 3 isoform B. (1141 aa)
NCOA1Nuclear receptor coactivator 1 isoform A. (1274 aa)
SP1Transcription factor Sp1. (746 aa)
VDRVitamin D3 receptor isoform B. (480 aa)
PPARABPeroxisome proliferator-activated receptor alpha. (438 aa)
PGR-1Progesterone receptor isoform B. (408 aa)
NR3C2Mineralocorticoid receptor isoform A. (1022 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (555 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (453 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (24%) [HD]