(5 nodes) tRNA-splicing ligase complex network (Alligator mississippiensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	FAM98B	Protein FAM98B. (341 aa)
	DDX1	ATP-dependent RNA helicase DDX1. (740 aa)
	RTCB	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (505 aa)
	CUNH2orf49	Ashwin. (242 aa)
	Y1Q_0019947	Uncharacterized protein. (264 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUNH2orf49	DDX1	A0A151NXQ6	A0A151N8W6	Ashwin.	ATP-dependent RNA helicase DDX1.	0.864
CUNH2orf49	FAM98B	A0A151NXQ6	A0A151MUS6	Ashwin.	Protein FAM98B.	0.883
CUNH2orf49	RTCB	A0A151NXQ6	A0A151NHW8	Ashwin.	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.	0.930
CUNH2orf49	Y1Q_0019947	A0A151NXQ6	A0A151PDN9	Ashwin.	Uncharacterized protein.	0.867
DDX1	CUNH2orf49	A0A151N8W6	A0A151NXQ6	ATP-dependent RNA helicase DDX1.	Ashwin.	0.864
DDX1	FAM98B	A0A151N8W6	A0A151MUS6	ATP-dependent RNA helicase DDX1.	Protein FAM98B.	0.925
DDX1	RTCB	A0A151N8W6	A0A151NHW8	ATP-dependent RNA helicase DDX1.	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.	0.985
DDX1	Y1Q_0019947	A0A151N8W6	A0A151PDN9	ATP-dependent RNA helicase DDX1.	Uncharacterized protein.	0.971
FAM98B	CUNH2orf49	A0A151MUS6	A0A151NXQ6	Protein FAM98B.	Ashwin.	0.883
FAM98B	DDX1	A0A151MUS6	A0A151N8W6	Protein FAM98B.	ATP-dependent RNA helicase DDX1.	0.925
FAM98B	RTCB	A0A151MUS6	A0A151NHW8	Protein FAM98B.	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.	0.902
FAM98B	Y1Q_0019947	A0A151MUS6	A0A151PDN9	Protein FAM98B.	Uncharacterized protein.	0.925
RTCB	CUNH2orf49	A0A151NHW8	A0A151NXQ6	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.	Ashwin.	0.930
RTCB	DDX1	A0A151NHW8	A0A151N8W6	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.	ATP-dependent RNA helicase DDX1.	0.985
RTCB	FAM98B	A0A151NHW8	A0A151MUS6	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.	Protein FAM98B.	0.902
RTCB	Y1Q_0019947	A0A151NHW8	A0A151PDN9	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.	Uncharacterized protein.	0.922
Y1Q_0019947	CUNH2orf49	A0A151PDN9	A0A151NXQ6	Uncharacterized protein.	Ashwin.	0.867
Y1Q_0019947	DDX1	A0A151PDN9	A0A151N8W6	Uncharacterized protein.	ATP-dependent RNA helicase DDX1.	0.971
Y1Q_0019947	FAM98B	A0A151PDN9	A0A151MUS6	Uncharacterized protein.	Protein FAM98B.	0.925
Y1Q_0019947	RTCB	A0A151PDN9	A0A151NHW8	Uncharacterized protein.	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.	0.922