STRINGSTRING
SOCS2 SOCS2 PSMD14 PSMD14 PSMA3 PSMA3 PSMB1 PSMB1 Y1Q_0024416 Y1Q_0024416 PRPF38B PRPF38B USP24 USP24 PSMB4 PSMB4 PSMD4 PSMD4 DCUN1D1 DCUN1D1 GPS1 GPS1 UBQLN4 UBQLN4 NEDD8 NEDD8 DET1 DET1 COPS2 COPS2 HYKK HYKK UBL7 UBL7 SYNJ2BP-2 SYNJ2BP-2 DCAF5 DCAF5 PSMC3 PSMC3 DDB2 DDB2 PSMA1 PSMA1 COPS7A COPS7A DCAF6 DCAF6 PSMG1 PSMG1 UBLCP1 UBLCP1 IFRD2 IFRD2 PSMD5-1 PSMD5-1 PSMB7 PSMB7 PSME4 PSME4 COX20 COX20 UCHL5 UCHL5 RFWD2 RFWD2 CAND1-2 CAND1-2 UBA3 UBA3 PSMD6 PSMD6 VHL VHL Y1Q_0001781 Y1Q_0001781 ADPRHL ADPRHL COPS7B COPS7B PSMB8 PSMB8 PSMB9 PSMB9 TCEB1 TCEB1 PPP1R42 PPP1R42 COPS5 COPS5 PPP1R42L PPP1R42L GAS7 GAS7 Y1Q_0020670 Y1Q_0020670 KATNAL1 KATNAL1 POMP POMP KATNB1 KATNB1 WDR76 WDR76 KDM2A KDM2A DCAF4 DCAF4 FBXL19 FBXL19 ERCC8 ERCC8 TRAF7 TRAF7 PSMD1 PSMD1 Y1Q_0005128 Y1Q_0005128 MPND MPND DCUN1D3 DCUN1D3 PSMG3 PSMG3 COPS3 COPS3 PSMD12 PSMD12 SOCS4 SOCS4 MIB2 MIB2 FBXW9 FBXW9 Y1Q_0019034 Y1Q_0019034 NAE1 NAE1 Y1Q_0008616 Y1Q_0008616 PSMA5 PSMA5 UBE2F UBE2F PSMC5 PSMC5 RNF7 RNF7 Y1Q_0024516 Y1Q_0024516 OASL OASL Y1Q_0001042 Y1Q_0001042 DCAF10 DCAF10 USP14 USP14 PSMG2 PSMG2 PSMG4 PSMG4 TCEB2 TCEB2 PRDM10 PRDM10 PSMC4 PSMC4 DESI1 DESI1 RBX1 RBX1 AMN1 AMN1 WDTC1 WDTC1 PSMA6 PSMA6 UCHL3-1 UCHL3-1 SLITRK1-1 SLITRK1-1 KATNA1 KATNA1 PSME2 PSME2 PSME1 PSME1 CUL4B CUL4B PSMD10 PSMD10 Y1Q_0015515 Y1Q_0015515 PSMD7 PSMD7 DDA1-1 DDA1-1 PSMC2 PSMC2 PSMB11 PSMB11 PSMB5 PSMB5 PSMD9-1 PSMD9-1 Y1Q_0018768 Y1Q_0018768 Y1Q_0018767 Y1Q_0018767 KDM2B KDM2B PSMB6 PSMB6 CACUL1 CACUL1 EFHD1 EFHD1 DCAF8 DCAF8 UBFD1 UBFD1 DCUN1D2 DCUN1D2 CUL4A CUL4A ADPRHL1 ADPRHL1 PSMD13 PSMD13 Y1Q_0004499 Y1Q_0004499 DDB1 DDB1 PSMA7 PSMA7 ADRM1 ADRM1 COPS4 COPS4 PSMF1 PSMF1 DTL DTL UBE2M UBE2M PSMD3 PSMD3 PSMB3 PSMB3 Y1Q_0016694 Y1Q_0016694 Y1Q_0016697 Y1Q_0016697 CUL5 CUL5 DCUN1D5 DCUN1D5 PSMD2 PSMD2 PSMC1 PSMC1 Y1Q_0021564 Y1Q_0021564 PSMD11 PSMD11 CUL2 CUL2 FBXO9 FBXO9 LRR1 LRR1 PSMC6 PSMC6 CAND1 CAND1 PSMB2 PSMB2 COPS6 COPS6 ATAD2B-2 ATAD2B-2 FEM1C-2 FEM1C-2 PAAF1 PAAF1 PSMD8 PSMD8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS2Suppressor of cytokine signaling 2. (169 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (460 aa)
PSMA3Proteasome subunit alpha type. (256 aa)
PSMB1Proteasome subunit beta. (240 aa)
Y1Q_0024416Uncharacterized protein. (127 aa)
PRPF38BPre-mRNA-splicing factor 38B. (397 aa)
USP24Uncharacterized protein; Belongs to the peptidase C19 family. (2600 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (281 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform A. (381 aa)
DCUN1D1DCN1-like protein. (259 aa)
GPS1COP9 signalosome complex subunit 1 isoform A. (465 aa)
UBQLN4Ubiquilin-4 isoform B. (581 aa)
NEDD8NEDD8. (79 aa)
DET1DET1-like protein. (551 aa)
COPS2COP9 signalosome complex subunit 2 isoform B. (436 aa)
HYKKProteasome endopeptidase complex. (600 aa)
UBL7Ubiquitin-like protein 7. (519 aa)
SYNJ2BP-2Synaptojanin 2 binding protein. (196 aa)
DCAF5DDB1-and CUL4-associated factor 5. (880 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (404 aa)
DDB2DNA damage-binding protein 2. (517 aa)
PSMA1Proteasome subunit alpha type. (261 aa)
COPS7ACOP9 signalosome complex subunit 7a. (291 aa)
DCAF6DDB1-and CUL4-associated factor 6 isoform A. (869 aa)
PSMG1Proteasome assembly chaperone 1. (281 aa)
UBLCP1Ubiquitin-like domain-containing CTD phosphatase 1. (342 aa)
IFRD2Interferon-related developmental regulator 2 isoform A. (461 aa)
PSMD5-126S proteasome non-ATPase regulatory subunit 5 isoform B. (837 aa)
PSMB7Proteasome subunit beta. (274 aa)
PSME4Proteasome activator complex subunit 4. (1808 aa)
COX20Protein FAM36A isoform A. (181 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (314 aa)
RFWD2E3 ubiquitin-protein ligase RFWD2 isoform A. (796 aa)
CAND1-2TIP120 domain-containing protein. (1237 aa)
UBA3NEDD8-activating enzyme E1 catalytic subunit isoform A. (463 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (348 aa)
VHLVon Hippel-Lindau disease tumor suppressor. (174 aa)
Y1Q_0001781Ubiquitin-like domain-containing protein. (121 aa)
ADPRHLProtein ADP-ribosylarginine hydrolase. (350 aa)
COPS7BCOP9 signalosome complex subunit 7b. (293 aa)
PSMB8Proteasome subunit beta. (282 aa)
PSMB9Proteasome subunit beta. (216 aa)
TCEB1Transcription elongation factor B polypeptide 1; Belongs to the SKP1 family. (112 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (171 aa)
COPS5COP9 signalosome complex subunit 5. (149 aa)
PPP1R42LProtein phosphatase 1 regulatory subunit 42. (308 aa)
GAS7Growth arrest-specific protein 7 isoform A. (426 aa)
Y1Q_0020670COP9 signalosome complex subunit 4-like. (104 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily. (565 aa)
POMPProteasome maturation protein. (141 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (657 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (486 aa)
KDM2ALysine-specific demethylase 2A isoform B. (1229 aa)
DCAF4DDB1-and CUL4-associated factor 4 isoform A. (521 aa)
FBXL19F-box/LRR-repeat protein 19. (689 aa)
ERCC8DNA excision repair protein ERCC-8. (399 aa)
TRAF7E3 ubiquitin-protein ligase TRAF7. (670 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (963 aa)
Y1Q_0005128Proteasome subunit beta. (277 aa)
MPNDMPN domain-containing protein isoform A. (501 aa)
DCUN1D3DCN1-like protein. (304 aa)
PSMG3Proteasome assembly chaperone 3. (122 aa)
COPS3COP9 signalosome complex subunit 3. (423 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (441 aa)
SOCS4Suppressor of cytokine signaling 4. (321 aa)
MIB2Uncharacterized protein. (954 aa)
FBXW9F-box/WD repeat-containing protein 9. (457 aa)
Y1Q_0019034RPN1_C domain-containing protein. (356 aa)
NAE1NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (541 aa)
Y1Q_0008616HSA domain-containing protein. (1301 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
UBE2FNEDD8-conjugating enzyme UBE2F; Belongs to the ubiquitin-conjugating enzyme family. (220 aa)
PSMC5Proteasome (Prosome, macropain) 26S subunit, ATPase, 5; Belongs to the AAA ATPase family. (411 aa)
RNF7RING-box protein 2. (85 aa)
Y1Q_0024516Uncharacterized protein. (390 aa)
OASL2'-5'-oligoadenylate synthase-like protein. (518 aa)
Y1Q_0001042Proteasome-associated ECM29-like protein. (1841 aa)
DCAF10DDB1-and CUL4-associated factor 10. (413 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (492 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (266 aa)
PSMG4Proteasome assembly chaperone 4. (85 aa)
TCEB2Transcription elongation factor B polypeptide 2. (115 aa)
PRDM10PR domain zinc finger protein 10 isoform A. (1160 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
DESI1Desumoylating isopeptidase 1. (169 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (104 aa)
AMN1AMN1-like protein. (259 aa)
WDTC1WD and tetratricopeptide repeats protein 1. (664 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
UCHL3-1Ubiquitin carboxyl-terminal hydrolase. (239 aa)
SLITRK1-1SLIT and NTRK-like protein 1 isoform B. (604 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (532 aa)
PSME2Proteasome activator complex subunit 2. (242 aa)
PSME1Proteasome activator complex subunit 1. (150 aa)
CUL4BCullin-4B; Belongs to the cullin family. (614 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (226 aa)
Y1Q_0015515Cullin domain-containing protein; Belongs to the cullin family. (160 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
DDA1-1DET1-and DDB1-associated protein 1 isoform C. (111 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMB11Proteasome subunit beta. (261 aa)
PSMB5Proteasome subunit beta type-5. (211 aa)
PSMD9-126S proteasome non-ATPase regulatory subunit 9 isoform B. (205 aa)
Y1Q_0018768JmjC domain-containing protein. (121 aa)
Y1Q_0018767Uncharacterized protein. (203 aa)
KDM2BLysine-specific demethylase 2B isoform E. (938 aa)
PSMB6Proteasome subunit beta. (227 aa)
CACUL1CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family. (317 aa)
EFHD1EF-hand domain-containing protein D1. (145 aa)
DCAF8DDB1-and CUL4-associated factor 8. (642 aa)
UBFD1Ubiquitin domain-containing protein UBFD1. (260 aa)
DCUN1D2DCN1-like protein. (311 aa)
CUL4ACULLIN_2 domain-containing protein; Belongs to the cullin family. (763 aa)
ADPRHL1Protein ADP-ribosylarginine hydrolase-like protein 1. (1704 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
Y1Q_0004499Uncharacterized protein. (568 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
ADRM1Proteasomal ubiquitin receptor ADRM1. (405 aa)
COPS4COP9 signalosome complex subunit 4. (190 aa)
PSMF1Proteasome inhibitor PI31 subunit. (273 aa)
DTLDenticleless protein-like protein isoform B. (745 aa)
UBE2MNEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (521 aa)
PSMB3Proteasome subunit beta. (205 aa)
Y1Q_0016694Ubiquilin-1-like. (588 aa)
Y1Q_0016697Ubiquilin-1-like. (432 aa)
CUL5Cullin-5; Belongs to the cullin family. (780 aa)
DCUN1D5DCN1-like protein. (237 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2. (513 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
Y1Q_0021564Ubiquitin-like domain-containing protein. (174 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (518 aa)
CUL2Cullin-2; Belongs to the cullin family. (720 aa)
FBXO9F-box only protein 9 isoform A. (389 aa)
LRR1Leucine-rich repeat protein 1. (370 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
CAND1Cullin-associated NEDD8-dissociated protein 1. (1230 aa)
PSMB2Proteasome subunit beta. (201 aa)
COPS6COP9 signalosome complex subunit 6. (297 aa)
ATAD2B-2Bromo domain-containing protein. (1418 aa)
FEM1C-2Uncharacterized protein. (617 aa)
PAAF1Proteasomal ATPase-associated factor 1. (392 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (257 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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