34 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PATL2-1	PAT1-like protein 2 isoform B. (800 aa)
	SAMD4B	Smaug-like protein 2. (684 aa)
	EXOSC8	Exosome complex component RRP43. (269 aa)
	DCP2	M7GpppN-mRNA hydrolase isoform B. (418 aa)
	PARN	Poly(A)-specific ribonuclease PARN. (638 aa)
	SAMD4A	SAM domain-containing protein. (705 aa)
	EXOSC5	Exosome complex component RRP46. (200 aa)
	CNOT6L-2	Endo/exonuclease/phosphatase domain-containing protein. (594 aa)
	RC3H2	Roquin-2 isoform C. (1099 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (133 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1115 aa)
	DCPS	M7GpppX diphosphatase. (303 aa)
	NOCT	Nocturnin. (420 aa)
	DCP1B-1	mRNA-decapping enzyme 1B isoform A. (492 aa)
	MLH1	DNA mismatch repair protein Mlh1. (750 aa)
	ZFP36L2	Tis11B_N domain-containing protein. (90 aa)
	LRRC27	Leucine-rich repeat-containing protein 27 isoform C. (481 aa)
	CNOT7	CCR4-NOT transcription complex subunit 7. (262 aa)
	CNOT6L	CCR4-NOT transcription complex subunit 6-like. (627 aa)
	CNOT3-1	CCR4-NOT transcription complex subunit 3. (456 aa)
	CNOT3-2	CCR4-NOT transcription complex subunit 3. (264 aa)
	PDE12	2',5'-phosphodiesterase 12. (423 aa)
	DCP1A	mRNA-decapping enzyme 1A. (426 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (760 aa)
	CNOT1	CCR4-NOT transcription complex subunit 1 isoform B. (2350 aa)
	EXOSC3	Exosome complex component RRP40. (257 aa)
	PATL1	PAT1-like protein 1. (770 aa)
	PNLDC1	Poly(A)-specific ribonuclease PARN-like domain-containing protein 1 isoform B. (534 aa)
	EXOSC9	Exosome complex component RRP45. (439 aa)
	CNOT2	CCR4-NOT transcription complex subunit 2 isoform A. (561 aa)
	ZFP36L1	Zinc finger protein 36, C3H1 type-like 1. (335 aa)
	CNOT8	CCR4-NOT transcription complex subunit 8. (292 aa)
	RC3H2-2	Uncharacterized protein. (1160 aa)
	EXOSC2	Exosome complex component RRP4. (294 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNOT1	CNOT2	A0A151MSK9	A0A151PFE7	CCR4-NOT transcription complex subunit 1 isoform B.	CCR4-NOT transcription complex subunit 2 isoform A.	0.997
CNOT1	CNOT3-1	A0A151MSK9	A0A151M4T2	CCR4-NOT transcription complex subunit 1 isoform B.	CCR4-NOT transcription complex subunit 3.	0.971
CNOT1	CNOT3-2	A0A151MSK9	A0A151M4S5	CCR4-NOT transcription complex subunit 1 isoform B.	CCR4-NOT transcription complex subunit 3.	0.971
CNOT1	CNOT6L	A0A151MSK9	A0A151M7E6	CCR4-NOT transcription complex subunit 1 isoform B.	CCR4-NOT transcription complex subunit 6-like.	0.909
CNOT1	CNOT6L-2	A0A151MSK9	A0A151MPS7	CCR4-NOT transcription complex subunit 1 isoform B.	Endo/exonuclease/phosphatase domain-containing protein.	0.909
CNOT1	CNOT7	A0A151MSK9	A0A151PAJ2	CCR4-NOT transcription complex subunit 1 isoform B.	CCR4-NOT transcription complex subunit 7.	0.986
CNOT1	CNOT8	A0A151MSK9	A0A151MEQ5	CCR4-NOT transcription complex subunit 1 isoform B.	CCR4-NOT transcription complex subunit 8.	0.981
CNOT1	DCP1A	A0A151MSK9	A0A151MZ15	CCR4-NOT transcription complex subunit 1 isoform B.	mRNA-decapping enzyme 1A.	0.484
CNOT1	DCP1B-1	A0A151MSK9	A0A151NIM7	CCR4-NOT transcription complex subunit 1 isoform B.	mRNA-decapping enzyme 1B isoform A.	0.472
CNOT1	DCP2	A0A151MSK9	A0A151PIK1	CCR4-NOT transcription complex subunit 1 isoform B.	M7GpppN-mRNA hydrolase isoform B.	0.806
CNOT1	LRRC27	A0A151MSK9	A0A151P4F3	CCR4-NOT transcription complex subunit 1 isoform B.	Leucine-rich repeat-containing protein 27 isoform C.	0.909
CNOT1	LSM1	A0A151MSK9	A0A151NBT2	CCR4-NOT transcription complex subunit 1 isoform B.	U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.	0.615
CNOT1	NOCT	A0A151MSK9	A0A151NHA8	CCR4-NOT transcription complex subunit 1 isoform B.	Nocturnin.	0.837
CNOT1	PAN2	A0A151MSK9	A0A151NG96	CCR4-NOT transcription complex subunit 1 isoform B.	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...]	0.588
CNOT1	PAN3	A0A151MSK9	A0A151MSA7	CCR4-NOT transcription complex subunit 1 isoform B.	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]	0.447
CNOT1	PARN	A0A151MSK9	A0A151N1A7	CCR4-NOT transcription complex subunit 1 isoform B.	Poly(A)-specific ribonuclease PARN.	0.498
CNOT1	PATL1	A0A151MSK9	A0A151MUE3	CCR4-NOT transcription complex subunit 1 isoform B.	PAT1-like protein 1.	0.836
CNOT1	PATL2-1	A0A151MSK9	A0A151MAD1	CCR4-NOT transcription complex subunit 1 isoform B.	PAT1-like protein 2 isoform B.	0.836
CNOT1	PDE12	A0A151MSK9	A0A151MZ10	CCR4-NOT transcription complex subunit 1 isoform B.	2',5'-phosphodiesterase 12.	0.837
CNOT1	PNLDC1	A0A151MSK9	A0A151M2C7	CCR4-NOT transcription complex subunit 1 isoform B.	Poly(A)-specific ribonuclease PARN-like domain-containing protein 1 isoform B.	0.402