node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGO2 | EIF4E1B | A0A151P872 | A0A151NYG2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | 0.415 |
AGO2 | NCBP2 | A0A151P872 | A0A151N774 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.514 |
CYFIP1-2 | EIF4E | A0A151NXH9 | A0A151NMP7 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | 0.948 |
CYFIP1-2 | EIF4E1B | A0A151NXH9 | A0A151NYG2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | 0.948 |
CYFIP1-2 | EIF4E2-1 | A0A151NXH9 | A0A151PEJ7 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | Eukaryotic translation initiation factor 4E type 2 isoform B; Belongs to the eukaryotic initiation factor 4E family. | 0.900 |
EIF4E | CYFIP1-2 | A0A151NMP7 | A0A151NXH9 | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.948 |
EIF4E | EIF4E1B | A0A151NMP7 | A0A151NYG2 | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | 0.901 |
EIF4E | EIF4E2-1 | A0A151NMP7 | A0A151PEJ7 | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | Eukaryotic translation initiation factor 4E type 2 isoform B; Belongs to the eukaryotic initiation factor 4E family. | 0.913 |
EIF4E | NCBP2 | A0A151NMP7 | A0A151N774 | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.610 |
EIF4E1B | AGO2 | A0A151NYG2 | A0A151P872 | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.415 |
EIF4E1B | CYFIP1-2 | A0A151NYG2 | A0A151NXH9 | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.948 |
EIF4E1B | EIF4E | A0A151NYG2 | A0A151NMP7 | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | 0.901 |
EIF4E1B | EIF4E2-1 | A0A151NYG2 | A0A151PEJ7 | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | Eukaryotic translation initiation factor 4E type 2 isoform B; Belongs to the eukaryotic initiation factor 4E family. | 0.913 |
EIF4E1B | NCBP2 | A0A151NYG2 | A0A151N774 | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.610 |
EIF4E2-1 | CYFIP1-2 | A0A151PEJ7 | A0A151NXH9 | Eukaryotic translation initiation factor 4E type 2 isoform B; Belongs to the eukaryotic initiation factor 4E family. | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. | 0.900 |
EIF4E2-1 | EIF4E | A0A151PEJ7 | A0A151NMP7 | Eukaryotic translation initiation factor 4E type 2 isoform B; Belongs to the eukaryotic initiation factor 4E family. | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | 0.913 |
EIF4E2-1 | EIF4E1B | A0A151PEJ7 | A0A151NYG2 | Eukaryotic translation initiation factor 4E type 2 isoform B; Belongs to the eukaryotic initiation factor 4E family. | Eukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. | 0.913 |
EIF4E3 | NCBP2 | A0A151MKB1 | A0A151N774 | Eukaryotic translation initiation factor 4E type 3; Belongs to the eukaryotic initiation factor 4E family. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.467 |
NCBP2 | AGO2 | A0A151N774 | A0A151P872 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.514 |
NCBP2 | EIF4E | A0A151N774 | A0A151NMP7 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | 0.610 |