203 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CACNG5	Voltage-dependent calcium channel gamma-5 subunit. (294 aa)
	CLCN2	Chloride channel protein 2. (307 aa)
	CATSPER2	Cation channel sperm-associated protein 2. (578 aa)
	KCNS3A	Potassium voltage-gated channel subfamily S member 3; Belongs to the potassium channel family. (555 aa)
	Y1Q_0004177	CaMBD domain-containing protein. (688 aa)
	LYSMD3	LysM and putative peptidoglycan-binding domain-containing protein 3. (313 aa)
	CACNA1F	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1276 aa)
	Y1Q_0006643	Ca_chan_IQ domain-containing protein. (672 aa)
	KCNQ2	Potassium voltage-gated channel subfamily KQT member 2 isoform A; Belongs to the potassium channel family. (682 aa)
	KCND3	Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (346 aa)
	KCNC2	Ion_trans domain-containing protein; Belongs to the potassium channel family. (497 aa)
	ANO6	Anoctamin. (930 aa)
	Y1Q_0019676	Uncharacterized protein; Belongs to the potassium channel family. (301 aa)
	Y1Q_0014536	Uncharacterized protein. (1245 aa)
	Y1Q_0014378	Uncharacterized protein. (92 aa)
	Y1Q_0013976	Ion_trans domain-containing protein; Belongs to the potassium channel family. (100 aa)
	Y1Q_0014535	Uncharacterized protein. (315 aa)
	Y1Q_0014534	Uncharacterized protein. (1079 aa)
	Y1Q_0014532	Uncharacterized protein. (1758 aa)
	KCNH8	Potassium voltage-gated channel subfamily H member 8 isoform A. (1163 aa)
	CACNB2	SH3 domain-containing protein. (612 aa)
	Y1Q_0018365	Uncharacterized protein. (137 aa)
	SCN4A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1697 aa)
	CLCN1	Chloride channel protein 1 isoform E. (1017 aa)
	KCNH4	Potassium voltage-gated channel subfamily H member 4 isoform B. (1239 aa)
	Y1Q_0018299	Uncharacterized protein. (488 aa)
	CLCN4	Chloride channel protein. (866 aa)
	KCNK10	Potassium channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (573 aa)
	KCNIP4	Kv channel-interacting protein 4. (233 aa)
	KCNK12	Potassium channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (401 aa)
	CLIC2	Chloride intracellular channel protein 2. (247 aa)
	KCNQ3	Potassium voltage-gated channel subfamily KQT member 3 isoform B. (970 aa)
	KCNQ1L	Potassium voltage-gated channel subfamily KQT member 1 isoform C; Belongs to the potassium channel family. (477 aa)
	Y1Q_0016832	BTB domain-containing protein; Belongs to the potassium channel family. (514 aa)
	Y1Q_0007347	Chloride channel protein. (821 aa)
	Y1Q_0016858	KCNQ_channel domain-containing protein. (128 aa)
	KCNA1	BTB domain-containing protein; Belongs to the potassium channel family. (493 aa)
	KCNA6	Uncharacterized protein; Belongs to the potassium channel family. (485 aa)
	CACNB1-2	SH3 domain-containing protein. (646 aa)
	CACNG7	Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
	CACNG8	Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (358 aa)
	CACNG6	Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (255 aa)
	KCNG3	Uncharacterized protein. (154 aa)
	Y1Q_0013651	RNA-binding protein with serine-rich domain 1-like. (134 aa)
	KCNH1	Potassium voltage-gated channel subfamily H member 1. (959 aa)
	KCNK2	Potassium channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (422 aa)
	KCNK16	Potassium channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (294 aa)
	KCNK5	Potassium channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (484 aa)
	KCNK17	Potassium channel subfamily K member 17; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (303 aa)
	Y1Q_0007229	PAS domain-containing protein. (103 aa)
	KCNH3	Potassium voltage-gated channel subfamily H member 3. (686 aa)
	TMC2	Transmembrane channel-like protein. (925 aa)
	HCN1	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (794 aa)
	KCNJ14	G protein-activated inward rectifier potassium channel 4-like. (609 aa)
	KCNB2	Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (674 aa)
	KCNG1	Uncharacterized protein; Belongs to the potassium channel family. (533 aa)
	Y1Q_0002754	Potassium voltage-gated channel subfamily B member 1-like. (206 aa)
	KCNS1	Potassium voltage-gated channel subfamily S member 1 isoform A; Belongs to the potassium channel family. (507 aa)
	KCNQ2-2	Uncharacterized protein; Belongs to the potassium channel family. (901 aa)
	SCN2B	Sodium channel subunit beta-2. (186 aa)
	TMEM109	Transmembrane protein 109. (182 aa)
	KCNK12-2	Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (270 aa)
	CACNG3	Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
	CALHM3	Calcium homeostasis modulator protein 3. (342 aa)
	Y1Q_0019889	BTB domain-containing protein. (212 aa)
	LRRC55	Leucine-rich repeat-containing protein 55. (281 aa)
	CALHM1	Calcium homeostasis modulator protein 1 isoform A. (338 aa)
	KCNK18	Potassium channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (368 aa)
	CATSPER1	Cation channel sperm-associated protein 1. (310 aa)
	QTRT1	Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (1506 aa)
	HVCN1	Voltage-gated hydrogen channel 1. (239 aa)
	NALCN	Sodium leak channel non-selective protein. (639 aa)
	NALCN-2	Uncharacterized protein. (1096 aa)
	CLIC1	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (328 aa)
	KCNIP1	Kv channel-interacting protein 1. (232 aa)
	SCN3B-1	Sodium channel subunit beta-3 isoform B. (222 aa)
	CACNA2D1	Calcium channel, voltage-dependent, alpha 2/delta subunit 1 preproprotein isoform B. (989 aa)
	Y1Q_0023404	Uncharacterized protein. (118 aa)
	KCNIP2	Kv channel-interacting protein 2. (259 aa)
	Y1Q_0015599	Potassium voltage-gated channel subfamily C member 1-like; Belongs to the potassium channel family. (431 aa)
	PKD2	EF-hand domain-containing protein. (818 aa)
	KCNG2	Potassium voltage-gated channel subfamily G member 2; Belongs to the potassium channel family. (510 aa)
	KCNE3	Potassium voltage-gated channel subfamily E member 3. (100 aa)
	KCNT2	Potassium channel subfamily T member 2 isoform B. (1174 aa)
	SCN1B	Sodium channel subunit beta-1. (219 aa)
	GRIN2D	Uncharacterized protein. (1373 aa)
	KCNN2	Small conductance calcium-activated potassium channel protein 2. (582 aa)
	CACHD1	VWFA and cache domain-containing protein 1 isoform A. (1223 aa)
	KCNJ11	ATP-sensitive inward rectifier potassium channel 11. (420 aa)
	CACNA1C	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1954 aa)
	Y1Q_0024309	Uncharacterized protein. (214 aa)
	CACNA2D4-2	VWFA domain-containing protein. (1071 aa)
	CACNG2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
	KCNJ4-2	Uncharacterized protein. (457 aa)
	Y1Q_0024062	Voltage-dependent T-type calcium channel subunit alpha-1H-like. (152 aa)
	Y1Q_0024060	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2005 aa)
	CLCN7	Chloride channel protein. (760 aa)
	KCNJ5	G protein-activated inward rectifier potassium channel 4 isoform A. (440 aa)
	KCNJ1	ATP-sensitive inward rectifier potassium channel 1. (297 aa)
	CATSPER4	Cation channel sperm-associated protein 4 isoform B. (521 aa)
	KCNG2-2	BTB domain-containing protein; Belongs to the potassium channel family. (517 aa)
	GRIN3A	Glutamate receptor ionotropic, NMDA 3A isoform A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1085 aa)
	VDAC3	Voltage-dependent anion-selective channel protein 3. (296 aa)
	Y1Q_0011941	Uncharacterized protein; Belongs to the potassium channel family. (460 aa)
	KCNMA1	Calcium-activated potassium channel subunit alpha-1 isoform E. (1062 aa)
	KCNA7	BTB domain-containing protein; Belongs to the potassium channel family. (485 aa)
	Y1Q_0004744	Protein kinase domain-containing protein. (161 aa)
	CLIC5	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (579 aa)
	KCNAB1	Voltage-gated potassium channel subunit beta-1. (380 aa)
	KCNC1	Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (396 aa)
	KCNE4	Potassium voltage-gated channel subfamily E member 4. (197 aa)
	ITGAV-2	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1046 aa)
	CACNA1E	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1843 aa)
	KCNA10	Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (574 aa)
	KCNC4	Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (595 aa)
	KCNA10-2	BTB domain-containing protein; Belongs to the potassium channel family. (520 aa)
	KCNA2	BTB domain-containing protein; Belongs to the potassium channel family. (499 aa)
	KCNF1	Potassium voltage-gated channel subfamily F member 1 isoform A; Belongs to the potassium channel family. (489 aa)
	CLCN2-2	Chloride channel protein 2-like; Belongs to the chloride channel (TC 2.A.49) family. (560 aa)
	TPCN1	Two pore calcium channel protein 1. (802 aa)
	KCNAB3	Aldo_ket_red domain-containing protein. (343 aa)
	CLCN6	Chloride transport protein 6; Belongs to the chloride channel (TC 2.A.49) family. (865 aa)
	KCNAB2	Aldo_ket_red domain-containing protein. (331 aa)
	GRIN2B	Glutamate receptor ionotropic, NMDA 2B. (1389 aa)
	Y1Q_0016435	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1961 aa)
	CACNG1	Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
	CACNG4	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
	KCNJ12	Uncharacterized protein. (429 aa)
	KCNJ4	Inward rectifier potassium channel 4. (425 aa)
	KCNJ16	Inward rectifier potassium channel 16. (424 aa)
	CACNA1I	Voltage-dependent T-type calcium channel subunit alpha-1I isoform B. (2248 aa)
	Y1Q_0008161	Uncharacterized protein. (206 aa)
	GRIN2A	Uncharacterized protein. (636 aa)
	CACNA2D4	Voltage-dependent calcium channel subunit alpha-2/delta-4 isoform C. (838 aa)
	CACNA1D	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2184 aa)
	KCNH2-2	Cyclic nucleotide-binding domain-containing protein. (1019 aa)
	SCN4B	Sodium channel subunit beta-4. (241 aa)
	KCNS2	Potassium voltage-gated channel subfamily S member 2; Belongs to the potassium channel family. (477 aa)
	KCNV1	Potassium voltage-gated channel subfamily V member 1; Belongs to the potassium channel family. (410 aa)
	HCN1-2	Cyclic nucleotide-binding domain-containing protein. (507 aa)
	Y1Q_0017166	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (198 aa)
	DDX43	Putative ATP-dependent RNA helicase DDX43 isoform A; Belongs to the potassium channel family. (1037 aa)
	KCND3-2	BTB domain-containing protein; Belongs to the potassium channel family. (657 aa)
	HCN3	Cyclic nucleotide-binding domain-containing protein. (628 aa)
	Y1Q_0005198	Uncharacterized protein. (108 aa)
	KCNMA1-2	Uncharacterized protein. (1058 aa)
	VDAC2	Voltage-dependent anion-selective channel protein 2. (303 aa)
	SCN8A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2018 aa)
	KCNN3	Small conductance calcium-activated potassium channel protein 3. (238 aa)
	KCNH8-2	Uncharacterized protein. (816 aa)
	KCNJ10	ATP-sensitive inward rectifier potassium channel 10. (378 aa)
	KCNJ9	Uncharacterized protein. (415 aa)
	Y1Q_0003885	Chloride channel protein. (814 aa)
	KCNB2-2	Ion_trans domain-containing protein; Belongs to the potassium channel family. (715 aa)
	MARCKSL1	MARCKS-related protein. (243 aa)
	CLIC4-1	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (374 aa)
	HCN4	Cyclic nucleotide-binding domain-containing protein. (770 aa)
	CACNA1A	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2207 aa)
	CLCNKB	Chloride channel protein. (700 aa)
	Y1Q_0004298	Uncharacterized protein. (193 aa)
	CACNA1E-2	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2286 aa)
	SNAP25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
	KCNT1	Uncharacterized protein. (1201 aa)
	NCS1	Neuronal calcium sensor 1. (196 aa)
	CACNA1B	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2363 aa)
	CACNA2D2	VWFA domain-containing protein. (833 aa)
	GRIN1	Glutamate receptor ionotropic, NMDA 1 isoform A. (885 aa)
	Y1Q_0005457	Voltage-dependent calcium channel subunit alpha-2/delta-2-like. (125 aa)
	Y1Q_0005453	VWA_N domain-containing protein. (152 aa)
	KCNJ15	ATP-sensitive inward rectifier potassium channel 15. (407 aa)
	KCNJ6	IRK_C domain-containing protein. (107 aa)
	KCNE2	Potassium voltage-gated channel subfamily E member 2. (123 aa)
	CLIC6	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (249 aa)
	GPR89B	Golgi pH regulator B. (456 aa)
	CACNB3	SH3 domain-containing protein. (479 aa)
	KCNQ1	Potassium voltage-gated channel subfamily KQT member 1 isoform A; Belongs to the potassium channel family. (692 aa)
	Y1Q_0000714	BTB domain-containing protein. (242 aa)
	KCNJ11-2	Uncharacterized protein. (394 aa)
	KCNA4	BTB domain-containing protein; Belongs to the potassium channel family. (660 aa)
	LYSMD4	LysM and putative peptidoglycan-binding domain-containing protein 4. (306 aa)
	KCNV2	Potassium voltage-gated channel subfamily V member 2; Belongs to the potassium channel family. (570 aa)
	LRRC38	Leucine-rich repeat-containing protein 38. (261 aa)
	KCND1	BTB domain-containing protein; Belongs to the potassium channel family. (624 aa)
	CATSPER3	Cation channel sperm-associated protein 3 isoform A. (403 aa)
	VDAC1	Voltage-dependent anion-selective channel protein 1. (581 aa)
	Y1Q_0014613	Uncharacterized protein. (157 aa)
	KCNK1	Potassium channel subfamily K member. (340 aa)
	OPRM1	Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (399 aa)
	KCNH5	Uncharacterized protein. (989 aa)
	KCNK4	Potassium channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (330 aa)
	TPCN3	Two-pore calcium channel 3. (755 aa)
	TMEM37	Voltage-dependent calcium channel gamma-like subunit. (132 aa)
	CACNB1	Voltage-dependent L-type calcium channel subunit beta-1 isoform A. (486 aa)
	KCNJ3	G protein-activated inward rectifier potassium channel 1. (497 aa)
	Y1Q_0011568	Potassium voltage-gated channel subfamily H member 7-like. (122 aa)
	KCNH2	Potassium voltage-gated channel subfamily H member 2 isoform B. (1103 aa)
	SCN2A	Uncharacterized protein. (1805 aa)
	Y1Q_0011560	Uncharacterized protein. (1595 aa)
	Y1Q_0011551	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1855 aa)
	Y1Q_0011556	CSRNP_N domain-containing protein. (134 aa)
	Y1Q_0011553	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1910 aa)
	GRIN2B-2	Uncharacterized protein. (1429 aa)
	KCNIP3-1	Calsenilin isoform B. (256 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACHD1	CACNB1	A0A151NJE9	A0A151M0L6	VWFA and cache domain-containing protein 1 isoform A.	Voltage-dependent L-type calcium channel subunit beta-1 isoform A.	0.525
CACHD1	CACNB1-2	A0A151NJE9	A0A151P6C5	VWFA and cache domain-containing protein 1 isoform A.	SH3 domain-containing protein.	0.525
CACHD1	CACNB2	A0A151NJE9	A0A151PCC8	VWFA and cache domain-containing protein 1 isoform A.	SH3 domain-containing protein.	0.525
CACHD1	CACNB3	A0A151NJE9	A0A151MCH8	VWFA and cache domain-containing protein 1 isoform A.	SH3 domain-containing protein.	0.525
CACHD1	CACNG1	A0A151NJE9	A0A151N2L1	VWFA and cache domain-containing protein 1 isoform A.	Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.	0.562
CACHD1	Y1Q_0014378	A0A151NJE9	A0A151PDB2	VWFA and cache domain-containing protein 1 isoform A.	Uncharacterized protein.	0.525
CACNA1A	CACNA1B	A0A151ML34	A0A151MF56	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.	0.901
CACNA1A	CACNA1C	A0A151ML34	A0A151NIP0	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.564
CACNA1A	CACNA1D	A0A151ML34	A0A151MZ58	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.548
CACNA1A	CACNA1E	A0A151ML34	A0A151N8W8	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.541
CACNA1A	CACNA1E-2	A0A151ML34	A0A151MIB9	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.	0.902
CACNA1A	CACNA1F	A0A151ML34	A0A151PH94	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.	0.566
CACNA1A	CACNA1I	A0A151ML34	A0A151N255	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent T-type calcium channel subunit alpha-1I isoform B.	0.563
CACNA1A	CACNA2D1	A0A151ML34	A0A151NPE7	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Calcium channel, voltage-dependent, alpha 2/delta subunit 1 preproprotein isoform B.	0.748
CACNA1A	CACNA2D2	A0A151ML34	A0A151MEX4	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	VWFA domain-containing protein.	0.583
CACNA1A	CACNA2D4	A0A151ML34	A0A151MZB3	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent calcium channel subunit alpha-2/delta-4 isoform C.	0.547
CACNA1A	CACNA2D4-2	A0A151ML34	A0A151NIH0	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	VWFA domain-containing protein.	0.547
CACNA1A	CACNB1	A0A151ML34	A0A151M0L6	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	Voltage-dependent L-type calcium channel subunit beta-1 isoform A.	0.808
CACNA1A	CACNB1-2	A0A151ML34	A0A151P6C5	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	SH3 domain-containing protein.	0.736
CACNA1A	CACNB2	A0A151ML34	A0A151PCC8	Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.	SH3 domain-containing protein.	0.736

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