STRINGSTRING
CACNB1 CACNB1 LAMB2 LAMB2 Y1Q_0001496 Y1Q_0001496 GPHN GPHN PPFIBP2-2 PPFIBP2-2 CACNB3 CACNB3 APP APP Y1Q_0005609 Y1Q_0005609 PDZRN3-2 PDZRN3-2 PPFIBP2 PPFIBP2 COLQ-1 COLQ-1 KYL KYL CACNG4 CACNG4 AGRN AGRN ALS2 ALS2 FNTA FNTA MUSK MUSK Y1Q_0024442 Y1Q_0024442 UNC13A UNC13A KY KY CACNG2 CACNG2 P2RX2 P2RX2 LRRK2 LRRK2 UNC13C UNC13C DCTN1 DCTN1 CACNB1-2 CACNB1-2 SNTA1 SNTA1 DOK7-1 DOK7-1 CACNB2 CACNB2 PDZRN3 PDZRN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNB1Voltage-dependent L-type calcium channel subunit beta-1 isoform A. (486 aa)
LAMB2Uncharacterized protein. (1523 aa)
Y1Q_0001496Unc-13-like protein C-like. (271 aa)
GPHNGephyrin. (1005 aa)
PPFIBP2-2Uncharacterized protein. (972 aa)
CACNB3SH3 domain-containing protein. (479 aa)
APPBPTI/Kunitz inhibitor domain-containing protein. (743 aa)
Y1Q_0005609Uncharacterized protein. (1687 aa)
PDZRN3-2Uncharacterized protein. (933 aa)
PPFIBP2Liprin-beta-2 isoform A. (1034 aa)
COLQ-1Acetylcholinesterase collagenic tail peptide isoform B. (508 aa)
KYLKyphoscoliosis peptidase. (749 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
AGRNAgrin isoform C. (2031 aa)
ALS2Alsin. (1647 aa)
FNTAProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha isoform B. (380 aa)
MUSKMuscle, skeletal receptor tyrosine-protein kinase. (898 aa)
Y1Q_0024442Unc-13-like protein A. (2195 aa)
UNC13AUnc-13-like protein A isoform B. (1779 aa)
KYKyphoscoliosis peptidase. (678 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (464 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2528 aa)
UNC13CUncharacterized protein. (386 aa)
DCTN1Dynactin subunit 1 isoform B. (1257 aa)
CACNB1-2SH3 domain-containing protein. (646 aa)
SNTA1Alpha-1-syntrophin. (489 aa)
DOK7-1Protein Dok-7 isoform C. (489 aa)
CACNB2SH3 domain-containing protein. (612 aa)
PDZRN3E3 ubiquitin-protein ligase PDZRN3. (794 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.