STRINGSTRING
Y1Q_0015287 Y1Q_0015287 CTNNB1 CTNNB1 GLI3 GLI3 BCL9L-1 BCL9L-1 CDH26 CDH26 SUFU SUFU FOXO4 FOXO4 PIN1 PIN1 TCF7L2 TCF7L2 KANK2 KANK2 AMER3 AMER3 CTNNA2 CTNNA2 Y1Q_0023889 Y1Q_0023889 AR AR AMER1 AMER1 ESR1 ESR1 RUVBL2 RUVBL2 MED12-2 MED12-2 Y1Q_0024039 Y1Q_0024039 CBY1 CBY1 CREBBP CREBBP KANK3 KANK3 Y1Q_0007617 Y1Q_0007617 ASH2L ASH2L MED12 MED12 CDH5 CDH5 KDM6B-2 KDM6B-2 AJAP1-1 AJAP1-1 LZIC LZIC SLC9A3R1 SLC9A3R1 AXIN2 AXIN2 SLC9A3R2 SLC9A3R2 TBL1X TBL1X Y1Q_0001731 Y1Q_0001731 CTNNA2-2 CTNNA2-2 Y1Q_0004916 Y1Q_0004916 SMAD7 SMAD7 NUMB NUMB DLG5 DLG5 VCL VCL AMER2 AMER2 NUMBL NUMBL BTRC BTRC FOXO3 FOXO3 LEF1 LEF1 SOX30 SOX30 CXADR CXADR BCL9 BCL9 Y1Q_0002887 Y1Q_0002887 PTPRJ PTPRJ KANK1 KANK1 TCF7 TCF7 TBL1XR1 TBL1XR1 Y1Q_0019052 Y1Q_0019052 PTPRM PTPRM GJA1 GJA1 DACT2 DACT2 PARK2L PARK2L PARK2 PARK2 DACT1 DACT1 TCF7L1 TCF7L1 Y1Q_0015290 Y1Q_0015290 Y1Q_0015289 Y1Q_0015289 CALCOCO1-1 CALCOCO1-1 AXIN1 AXIN1 APC2 APC2 PTPRU PTPRU APC APC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Y1Q_0015287Uncharacterized protein. (282 aa)
CTNNB1Catenin beta-1 isoform B. (783 aa)
GLI3Uncharacterized protein. (1572 aa)
BCL9L-1B-cell CLL/lymphoma 9-like protein isoform B. (1409 aa)
CDH26Cadherin-like protein 26. (823 aa)
SUFUSuppressor of fused homolog. (469 aa)
FOXO4Forkhead box protein O4. (480 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (159 aa)
TCF7L2Transcription factor 7-like 2 isoform A. (411 aa)
KANK2KN motif and ankyrin repeat domain-containing protein 2. (889 aa)
AMER3APC membrane recruitment protein 3. (345 aa)
CTNNA2Catenin alpha-2 isoform A. (939 aa)
Y1Q_0023889Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (629 aa)
ARAndrogen receptor. (634 aa)
AMER1APC membrane recruitment protein 1. (1161 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (461 aa)
MED12-2Med12 domain-containing protein. (2083 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
CBY1Chibby-like protein 1. (155 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
KANK3KN motif and ankyrin repeat domain-containing protein 3. (1036 aa)
Y1Q_0007617Fork-head domain-containing protein. (321 aa)
ASH2LSet1/Ash2 histone methyltransferase complex subunit ASH2. (591 aa)
MED12Mediator of RNA polymerase II transcription subunit 12 isoform B. (2143 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (733 aa)
KDM6B-2Uncharacterized protein. (1393 aa)
AJAP1-1Adherens junction-associated protein 1 isoform B. (203 aa)
LZICProtein LZIC isoform B. (413 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (342 aa)
AXIN2Axin-2 isoform B. (836 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (355 aa)
TBL1XUncharacterized protein. (525 aa)
Y1Q_0001731Calcium-binding and coiled-coil domain-containing protein 1-like. (188 aa)
CTNNA2-2Uncharacterized protein. (603 aa)
Y1Q_0004916Uncharacterized protein. (383 aa)
SMAD7Mothers against decapentaplegic homolog. (384 aa)
NUMBNumb-like protein isoform A. (629 aa)
DLG5Disks large-like protein 5; Belongs to the MAGUK family. (1973 aa)
VCLVinculin. (1066 aa)
AMER2APC membrane recruitment protein 2. (567 aa)
NUMBLPID domain-containing protein. (157 aa)
BTRCF-box/WD repeat-containing protein 1A isoform B. (626 aa)
FOXO3Forkhead box protein O3. (569 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform B. (391 aa)
SOX30Transcription factor SOX-30. (457 aa)
CXADRCoxsackievirus and adenovirus receptor. (355 aa)
BCL9B-cell CLL/lymphoma 9 protein. (1427 aa)
Y1Q_0002887Uncharacterized protein. (454 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta isoform A. (1187 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1. (919 aa)
TCF7Transcription factor 7 isoform A. (452 aa)
TBL1XR1F-box-like/WD repeat-containing protein TBL1XR1. (513 aa)
Y1Q_0019052NumbF domain-containing protein. (153 aa)
PTPRMReceptor-type tyrosine-protein phosphatase mu isoform C. (1440 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (405 aa)
DACT2Dapper-like protein 2. (760 aa)
PARK2LRBR-type E3 ubiquitin transferase. (180 aa)
PARK2E3 ubiquitin-protein ligase parkin isoform A. (280 aa)
DACT1Dapper-like protein 1. (722 aa)
TCF7L1Transcription factor 7-like 1 isoform D. (567 aa)
Y1Q_0015290Uncharacterized protein. (143 aa)
Y1Q_0015289Uncharacterized protein. (128 aa)
CALCOCO1-1Calcium-binding and coiled-coil domain-containing protein 1 isoform B. (566 aa)
AXIN1Uncharacterized protein. (892 aa)
APC2Uncharacterized protein. (2467 aa)
PTPRUUncharacterized protein. (1507 aa)
APCAdenomatous polyposis coli protein. (2841 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.