STRINGSTRING
POLDIP2 POLDIP2 NOCT NOCT MGAT3 MGAT3 TIMP3 TIMP3 METTL20 METTL20 GIPC2 GIPC2 LEPR-1 LEPR-1 SF3B3 SF3B3 SCFD1 SCFD1 FAM46B FAM46B MYCBP2 MYCBP2 VIP VIP RGP1 RGP1 ATRAID ATRAID EIF4G3 EIF4G3 ZDHHC7 ZDHHC7 RILP RILP LRRK2 LRRK2 FAM46D FAM46D SORL1 SORL1 DND1 DND1 UBXN1 UBXN1 TNF TNF OGT OGT SEC22B SEC22B TIMP2 TIMP2 FOXK2 FOXK2 PIN1 PIN1 SUFU SUFU BAG6 BAG6 SIRT6 SIRT6 PKP3 PKP3 Y1Q_0004499 Y1Q_0004499 RBM38 RBM38 DDIT4 DDIT4 Y1Q_0016721 Y1Q_0016721 HNRNPD HNRNPD CTSA CTSA A1CF A1CF DAP DAP PSMF1 PSMF1 GABARAPL2 GABARAPL2 RNF41 RNF41 TRAF5 TRAF5 ANGEL2 ANGEL2 LRPPRC LRPPRC TSPO2 TSPO2 CDK5RAP3 CDK5RAP3 PHB PHB IGF2BP3 IGF2BP3 ADRA1A ADRA1A E2F1 E2F1 TIGAR TIGAR APOBEC1A APOBEC1A PPARAB PPARAB F8A3 F8A3 DKC1 DKC1 TSPO TSPO BAG5 BAG5 NRDE2 NRDE2 NAF1 NAF1 RBM46 RBM46 TLK2-2 TLK2-2 STAT4 STAT4 WAC WAC Y1Q_0018461 Y1Q_0018461 MYD88 MYD88 FMC1 FMC1 MARCH7 MARCH7 DAPL1 DAPL1 CAMLG CAMLG HNRNPAB-1 HNRNPAB-1 PHAX PHAX RIC1 RIC1 Y1Q_0012698 Y1Q_0012698 PML PML KLHL40-2 KLHL40-2 STYX STYX Y1Q_0013170 Y1Q_0013170 MAD2L1 MAD2L1 MAPKAPK3 MAPKAPK3 IL10 IL10 MDM4 MDM4 SVIP SVIP LRRN4CL LRRN4CL LARP1B-1 LARP1B-1 ALAD ALAD TSC1 TSC1 FEZ2 FEZ2 UCHL5 UCHL5 DHX9 DHX9 PINK1 PINK1 SNX3 SNX3 TRAF3IP2 TRAF3IP2 FHIT FHIT TAF15 TAF15 WDR6 WDR6 IL1BL IL1BL RPL11-1 RPL11-1 MFSD2A MFSD2A Y1Q_0001844 Y1Q_0001844 THRAP3 THRAP3 ZCCHC17 ZCCHC17 PTPN3 PTPN3 Y1Q_0019033 Y1Q_0019033 HMGCR HMGCR SIRT2 SIRT2 TIMP4 TIMP4 AZIN2 AZIN2 MTMR9 MTMR9 TMEM39B TMEM39B RBM24 RBM24 PHF23-2 PHF23-2 LEP LEP TRDMT1 TRDMT1 IGF2BP3-2 IGF2BP3-2 FAM192A FAM192A Y1Q_0015766 Y1Q_0015766 N4BP1 N4BP1 CTSAL CTSAL FUS FUS Y1Q_0008456 Y1Q_0008456 LRIG2 LRIG2 FAM46A FAM46A BMF BMF MTMR9-2 MTMR9-2 NRBP2 NRBP2 TP53 TP53 FAM46C FAM46C GDNF GDNF PRKAA1-2 PRKAA1-2 PAIP1 PAIP1 AZIN1 AZIN1 LAPTM4B LAPTM4B DDRGK1 DDRGK1 TIMP1 TIMP1 DHX34 DHX34 GLTSCR2 GLTSCR2 RUBCN RUBCN PPIH PPIH WNT1 WNT1 CLEC16A CLEC16A USP7 USP7 GRIN2A GRIN2A PARN PARN SMG1 SMG1 Y1Q_0008161 Y1Q_0008161 FOXK1 FOXK1 FLCN FLCN SMCR8 SMCR8 TSC2 TSC2 QRICH2 QRICH2 DFFB DFFB MTOR MTOR MAD2L2 MAD2L2 CPTP CPTP KLHL22 KLHL22 EIF4ENIF1 EIF4ENIF1 AQP11 AQP11 PBK PBK NBAS NBAS PKP1 PKP1 FEZ1 FEZ1 Y1Q_0008603 Y1Q_0008603 PHF23-1 PHF23-1 BOLL-1 BOLL-1 SERPINE2 SERPINE2 DHX36 DHX36 DNAJB1 DNAJB1 LZTS1 LZTS1 ATP2B4-2 ATP2B4-2 BSCL2 BSCL2 BANP BANP Y1Q_0017188 Y1Q_0017188 SLC7A5 SLC7A5 NSUN2 NSUN2 ELAVL1 ELAVL1 Y1Q_0017061 Y1Q_0017061 PAPD7 PAPD7 USP14 USP14 GPLD1 GPLD1 IL10RA-1 IL10RA-1 USP19 USP19 TIRAP TIRAP CUNH16orf96 CUNH16orf96 GIPC3 GIPC3 IGF2BP2 IGF2BP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLDIP2Polymerase delta-interacting protein 2. (331 aa)
NOCTNocturnin. (420 aa)
MGAT3Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase isoform A. (439 aa)
TIMP3Metalloproteinase inhibitor 3. (212 aa)
METTL20Protein N-lysine methyltransferase METTL20. (241 aa)
GIPC2PDZ domain-containing protein GIPC2. (317 aa)
LEPR-1Leptin receptor isoform B. (528 aa)
SF3B3Splicing factor 3B subunit 3. (1217 aa)
SCFD1Sec1 family domain-containing protein 1; Belongs to the STXBP/unc-18/SEC1 family. (632 aa)
FAM46BUncharacterized protein. (308 aa)
MYCBP2E3 ubiquitin-protein ligase MYCBP2 isoform B. (4421 aa)
VIPVIP peptides. (234 aa)
RGP1RAB6A-GEF complex partner protein 2 isoform B. (377 aa)
ATRAIDAll-trans retinoic acid-induced differentiation factor. (213 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1080 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (261 aa)
RILPRab-interacting lysosomal protein. (152 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2528 aa)
FAM46DUncharacterized protein. (255 aa)
SORL1Sortilin-related receptor isoform B. (2170 aa)
DND1Dead end protein-like protein 1. (342 aa)
UBXN1UBX domain-containing protein 1. (320 aa)
TNFTumor necrosis factor. (231 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase subunit isoform B. (1075 aa)
SEC22BVesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family. (188 aa)
TIMP2Metalloproteinase inhibitor 2. (143 aa)
FOXK2Forkhead box protein K2. (562 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (159 aa)
SUFUSuppressor of fused homolog. (469 aa)
BAG6Large proline-rich protein BAG6. (945 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (357 aa)
PKP3Plakophilin-3. (833 aa)
Y1Q_0004499Uncharacterized protein. (568 aa)
RBM38RNA-binding protein 38. (215 aa)
DDIT4DNA damage-inducible transcript 4 protein. (172 aa)
Y1Q_0016721Uncharacterized protein. (349 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D0. (329 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (376 aa)
A1CFAPOBEC1 complementation factor isoform A. (595 aa)
DAPDeath-associated protein 1. (104 aa)
PSMF1Proteasome inhibitor PI31 subunit. (273 aa)
GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
RNF41E3 ubiquitin-protein ligase NRDP1. (261 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (588 aa)
ANGEL2Angel-like protein 2. (509 aa)
LRPPRCLeucine-rich PPR motif-containing protein, mitochondrial isoform A. (1357 aa)
TSPO2Translocator protein 2. (164 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3. (534 aa)
PHBProhibitin. (273 aa)
IGF2BP3Insulin-like growth factor 2 mRNA-binding protein 3 isoform B. (577 aa)
ADRA1AAlpha-1A adrenergic receptor. (335 aa)
E2F1Transcription factor E2F1. (426 aa)
TIGARFructose-2,6-bisphosphatase TIGAR. (272 aa)
APOBEC1AC->U-editing enzyme APOBEC-1. (198 aa)
PPARABPeroxisome proliferator-activated receptor alpha. (438 aa)
F8A3Factor VIII intron 22 protein-like. (360 aa)
DKC1H/ACA ribonucleoprotein complex subunit 4. (443 aa)
TSPOTranslocator protein. (244 aa)
BAG5BAG family molecular chaperone regulator 5. (450 aa)
NRDE2NRDE2-like protein. (1173 aa)
NAF1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (335 aa)
RBM46Putative RNA-binding protein 46. (546 aa)
TLK2-2Protein kinase domain-containing protein. (750 aa)
STAT4Signal transducer and activator of transcription. (849 aa)
WACWW domain-containing adapter protein with coiled-coil isoform B. (617 aa)
Y1Q_0018461Death-associated protein 1-like. (119 aa)
MYD88Myeloid differentiation primary response protein MyD88. (203 aa)
FMC1Uncharacterized protein. (113 aa)
MARCH7E3 ubiquitin-protein ligase MARCH7. (590 aa)
DAPL1Death-associated protein-like 1. (113 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (257 aa)
HNRNPAB-1Heterogeneous nuclear ribonucleoprotein A/B isoform B. (311 aa)
PHAXPhosphorylated adapter RNA export protein. (408 aa)
RIC1RAB6A-GEF complex partner protein 1 isoform C. (747 aa)
Y1Q_0012698RIC1 domain-containing protein. (492 aa)
PMLProtein PML isoform B. (586 aa)
KLHL40-2BTB domain-containing protein. (619 aa)
STYXSerine/threonine/tyrosine-interacting protein. (223 aa)
Y1Q_0013170Uncharacterized protein. (100 aa)
MAD2L1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (354 aa)
IL10Interleukin-10. (93 aa)
MDM4Protein Mdm4. (513 aa)
SVIPSmall VCP/p97-interacting protein. (79 aa)
LRRN4CLLRRN4 C-terminal-like protein. (261 aa)
LARP1B-1La-related protein 1B. (959 aa)
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (341 aa)
TSC1Hamartin isoform B. (1115 aa)
FEZ2Fasciculation and elongation protein zeta-2. (253 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (314 aa)
DHX9ATP-dependent RNA helicase A. (1546 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the arginase family. (851 aa)
SNX3Sorting nexin-3. (162 aa)
TRAF3IP2Adapter protein CIKS. (557 aa)
FHITBis(5'-adenosyl)-triphosphatase. (96 aa)
TAF15TATA-binding protein-associated factor 2N isoform B. (474 aa)
WDR6WD repeat-containing protein 6. (768 aa)
IL1BLInterleukin-1. (280 aa)
RPL11-160S ribosomal protein L11 isoform A; Belongs to the universal ribosomal protein uL5 family. (179 aa)
MFSD2ASodium-dependent lysophosphatidylcholine symporter 1 isoform A. (503 aa)
Y1Q_0001844Interleukin-1. (129 aa)
THRAP3Thyroid hormone receptor-associated protein 3. (659 aa)
ZCCHC17Nucleolar protein of. (235 aa)
PTPN3Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (939 aa)
Y1Q_0019033Eukaryotic translation initiation factor 4 gamma 1-like. (95 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (914 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (392 aa)
TIMP4Metalloproteinase inhibitor 4. (221 aa)
AZIN2Antizyme inhibitor 2; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (556 aa)
MTMR9Myotubularin-related protein 9 isoform A. (530 aa)
TMEM39BTransmembrane protein 39B. (459 aa)
RBM24RNA-binding protein 24. (227 aa)
PHF23-2PHD finger protein 23. (71 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (168 aa)
TRDMT1tRNA (Cytosine(38)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (400 aa)
IGF2BP3-2Uncharacterized protein. (568 aa)
FAM192AProtein FAM192A. (275 aa)
Y1Q_0015766Uncharacterized protein. (102 aa)
N4BP1NEDD4-binding protein 1. (938 aa)
CTSALCarboxypeptidase; Belongs to the peptidase S10 family. (642 aa)
FUSRNA-binding protein FUS. (289 aa)
Y1Q_0008456Uncharacterized protein. (141 aa)
LRIG2Uncharacterized protein. (1020 aa)
FAM46AProtein FAM46A. (400 aa)
BMFBcl-2-modifying factor. (217 aa)
MTMR9-2Myotubularin phosphatase domain-containing protein. (550 aa)
NRBP2Nuclear receptor-binding protein 2. (525 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
FAM46CUncharacterized protein. (423 aa)
GDNFGlial cell line-derived neurotrophic factor. (185 aa)
PRKAA1-2Non-specific serine/threonine protein kinase. (547 aa)
PAIP1Polyadenylate-binding protein-interacting protein 1. (406 aa)
AZIN1Antizyme inhibitor 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (449 aa)
LAPTM4BLysosomal-associated transmembrane protein 4B isoform B. (259 aa)
DDRGK1DDRGK domain-containing protein 1. (297 aa)
TIMP1Metalloproteinase inhibitor 1. (224 aa)
DHX34Putative ATP-dependent RNA helicase DHX34 isoform B. (822 aa)
GLTSCR2Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (409 aa)
RUBCNRun domain Beclin-1 interacting and cysteine-rich containing protein isoform A. (1001 aa)
PPIHPeptidyl-prolyl cis-trans isomerase H. (504 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
CLEC16AProtein CLEC16A isoform D. (1085 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1080 aa)
GRIN2AUncharacterized protein. (636 aa)
PARNPoly(A)-specific ribonuclease PARN. (638 aa)
SMG1Serine/threonine-protein kinase SMG1 isoform A; Belongs to the PI3/PI4-kinase family. (3628 aa)
Y1Q_0008161Uncharacterized protein. (206 aa)
FOXK1Forkhead box protein K1. (598 aa)
FLCNFolliculin. (629 aa)
SMCR8Smith-Magenis syndrome chromosomal region candidate 8 protein. (935 aa)
TSC2Tuberin isoform D. (1829 aa)
QRICH2Glutamine-rich protein 2. (773 aa)
DFFBDNAation factor subunit beta. (333 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (228 aa)
CPTPCeramide-1-phosphate transfer protein. (214 aa)
KLHL22Kelch-like protein 22. (793 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E transporter. (967 aa)
AQP11Aquaporin-11. (128 aa)
PBKLymphokine-activated killer T-cell-originated protein kinase. (325 aa)
NBASNeuroblastoma-amplified sequence isoform B. (2278 aa)
PKP1Plakophilin-1 isoform A. (731 aa)
FEZ1Fasciculation and elongation protein zeta-1 isoform A. (451 aa)
Y1Q_0008603Uncharacterized protein. (483 aa)
PHF23-1PHD finger protein 23. (297 aa)
BOLL-1Protein boule-like isoform A. (378 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (428 aa)
DHX36ATP-dependent RNA helicase DHX36. (991 aa)
DNAJB1DnaJ-like protein subfamily B member 1. (679 aa)
LZTS1Leucine zipper putative tumor suppressor 1. (613 aa)
ATP2B4-2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1293 aa)
BSCL2Seipin. (353 aa)
BANPProtein BANP. (508 aa)
Y1Q_0017188Uncharacterized protein. (164 aa)
SLC7A5Large neutral amino acids transporter small subunit 1. (511 aa)
NSUN2tRNA (Cytosine(34)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (812 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (334 aa)
Y1Q_0017061Uncharacterized protein. (161 aa)
PAPD7Non-canonical poly(A) RNA polymerase PAPD7 isoform A. (541 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (492 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (814 aa)
IL10RA-1Interleukin-10 receptor subunit alpha isoform A. (399 aa)
USP19Ubiquitin carboxyl-terminal hydrolase 19 isoform A. (1473 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein. (230 aa)
CUNH16orf96Uncharacterized protein. (658 aa)
GIPC3PDZ domain-containing protein GIPC3. (278 aa)
IGF2BP2RRM domain-containing protein. (527 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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