STRINGSTRING
PTK2 PTK2 TRAF3 TRAF3 JUP JUP ESYT2 ESYT2 Y1Q_0007359 Y1Q_0007359 PRMT1 PRMT1 GNAT1 GNAT1 STYK1 STYK1 GNAI3 GNAI3 CHMP4B CHMP4B Y1Q_0012034 Y1Q_0012034 STAC2 STAC2 MIEN1 MIEN1 PTK2B PTK2B TRAF5 TRAF5 STAC STAC GNG8 GNG8 GNA11-2 GNA11-2 S100A6 S100A6 FER FER CHMP4C CHMP4C GRAMD1AL GRAMD1AL GNA15 GNA15 SRC-2 SRC-2 Y1Q_0011203 Y1Q_0011203 GNAL GNAL OSBPL2 OSBPL2 Y1Q_0004473 Y1Q_0004473 SYK SYK FES FES HIP1R HIP1R FARP1 FARP1 Y1Q_0008573 Y1Q_0008573 GNAT3 GNAT3 RNF31 RNF31 Y1Q_0009425 Y1Q_0009425 GM2A GM2A PLEKHA4 PLEKHA4 PLEKHA4L PLEKHA4L GNG12 GNG12 THL THL YES1 YES1 GNAL-2 GNAL-2 IKBKB-2 IKBKB-2 Y1Q_0020951 Y1Q_0020951 PTPRC PTPRC KCNAB1 KCNAB1 PTPN7 PTPN7 GNAT2 GNAT2 GRAMD1A GRAMD1A HTRA2 HTRA2 ACP1-1 ACP1-1 GNAZ GNAZ AJAP1-1 AJAP1-1 KCNAB2 KCNAB2 GNG2 GNG2 GNA13 GNA13 GNA12 GNA12 GNG13 GNG13 LITAF LITAF SYAP1 SYAP1 SAMD10 SAMD10 SRMS SRMS PTK6 PTK6 TNK2 TNK2 GEM GEM SAMD12-1 SAMD12-1 ESYT1 ESYT1 BLK BLK GNAO1 GNAO1 MTSS1L MTSS1L CYLD CYLD RACGAP1 RACGAP1 SHANK3 SHANK3 SHANK2 SHANK2 G6PD G6PD Y1Q_0017685 Y1Q_0017685 LYN LYN LCK LCK LDLRAP1 LDLRAP1 GRAMD2 GRAMD2 Y1Q_0017822 Y1Q_0017822 NPHS2 NPHS2 RGS8 RGS8 RGS1 RGS1 HCK HCK Y1Q_0011868 Y1Q_0011868 SNAP25 SNAP25 TRAF1-1 TRAF1-1 TRAF2 TRAF2 GNB3 GNB3 TH TH TRAF6 TRAF6 MYZAP MYZAP Y1Q_0001438 Y1Q_0001438 MDP1 MDP1 PGM1 PGM1 Y1Q_0012624 Y1Q_0012624 GNA11 GNA11 SYK-2 SYK-2 CBY3 CBY3 GNB4 GNB4 SRC SRC FRK FRK GNG4 GNG4 EZR EZR SNX9 SNX9 AKAP5 AKAP5 Y1Q_0006941 Y1Q_0006941 PTPN4 PTPN4 ESYT3 ESYT3 GNG3 GNG3 ASPSCR1 ASPSCR1 ERRFI1 ERRFI1 CYLDL CYLDL PTPN3 PTPN3 CAV2 CAV2 SHROOM4 SHROOM4 MTSS1 MTSS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1052 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (553 aa)
JUPUncharacterized protein. (718 aa)
ESYT2Uncharacterized protein. (796 aa)
Y1Q_0007359Sec3-PIP2_bind domain-containing protein. (667 aa)
PRMT1Protein arginine N-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (379 aa)
GNAT1Uncharacterized protein. (343 aa)
STYK1Tyrosine-protein kinase STYK1 isoform A. (547 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (344 aa)
CHMP4BCharged multivesicular body protein 4b. (211 aa)
Y1Q_0012034B30.2/SPRY domain-containing protein. (292 aa)
STAC2SH3 and cysteine-rich domain-containing protein 2. (378 aa)
MIEN1Migration and invasion enhancer 1. (111 aa)
PTK2BUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (588 aa)
STACSH3 and cysteine-rich domain-containing protein. (452 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (155 aa)
GNA11-2Uncharacterized protein. (359 aa)
S100A6Protein S100; Belongs to the S-100 family. (93 aa)
FERTyrosine-protein kinase Fer. (954 aa)
CHMP4CCharged multivesicular body protein 4c. (221 aa)
GRAMD1ALGRAM domain-containing protein 1A. (335 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (396 aa)
SRC-2Tyrosine-protein kinase. (546 aa)
Y1Q_0011203Protein kinase domain-containing protein. (152 aa)
GNALGuanine nucleotide-binding protein G(Olf) subunit alpha isoform A. (412 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (474 aa)
Y1Q_0004473Tyrosine-protein kinase. (404 aa)
SYKTyrosine-protein kinase. (612 aa)
FESTyrosine-protein kinase. (627 aa)
HIP1RHuntingtin-interacting protein 1-related protein isoform A. (1040 aa)
FARP1Uncharacterized protein. (1063 aa)
Y1Q_0008573TNF receptor-associated factor 1-like. (331 aa)
GNAT3Guanine nucleotide-binding protein G(T) subunit alpha-3. (354 aa)
RNF31E3 ubiquitin-protein ligase RNF31. (955 aa)
Y1Q_0009425MTSS1-like protein. (281 aa)
GM2AGanglioside GM2 activator. (191 aa)
PLEKHA4Pleckstrin-like proteiny domain-containing family A member 4. (444 aa)
PLEKHA4LPleckstrin-like proteiny domain-containing family A member 4. (198 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
THLTyrosine 3-monooxygenase-like. (463 aa)
YES1Tyrosine-protein kinase. (1013 aa)
GNAL-2Uncharacterized protein. (384 aa)
IKBKB-2Uncharacterized protein. (757 aa)
Y1Q_0020951Uncharacterized protein. (453 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform D. (1209 aa)
KCNAB1Voltage-gated potassium channel subunit beta-1. (380 aa)
PTPN7Tyrosine-protein phosphatase non-receptor type 7. (339 aa)
GNAT2Guanine nucleotide-binding protein G(T) subunit alpha-2. (344 aa)
GRAMD1AGRAM domain-containing protein 1A. (155 aa)
HTRA2Serine protease HTRA2, mitochondrial. (313 aa)
ACP1-1Low molecular weight phosphotyrosine protein phosphatase isoform A. (158 aa)
GNAZGuanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
AJAP1-1Adherens junction-associated protein 1 isoform B. (203 aa)
KCNAB2Aldo_ket_red domain-containing protein. (331 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (228 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (422 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12 isoform A. (383 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LITAFLipopolysaccharide-induced tumor necrosis factor-alpha factor. (116 aa)
SYAP1Synapse-associated protein 1. (312 aa)
SAMD10Sterile alpha motif domain-containing protein 10. (195 aa)
SRMSTyrosine-protein kinase. (491 aa)
PTK6Tyrosine-protein kinase. (481 aa)
TNK2Activated CDC42 kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
GEMGTP-binding protein GEM. (337 aa)
SAMD12-1Sterile alpha motif domain-containing protein 12 isoform A. (183 aa)
ESYT1Extended synaptotagmin-1. (531 aa)
BLKTyrosine-protein kinase. (513 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (354 aa)
MTSS1LIMD domain-containing protein. (712 aa)
CYLDUncharacterized protein. (949 aa)
RACGAP1Rac GTPase-activating protein 1. (586 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3-like. (1242 aa)
SHANK2SH3 and multiple ankyrin repeat domains protein 2. (524 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (545 aa)
Y1Q_0017685Rac GTPase-activating protein 1-like. (449 aa)
LYNTyrosine-protein kinase. (562 aa)
LCKTyrosine-protein kinase. (545 aa)
LDLRAP1Low density lipoprotein receptor adapter protein 1. (302 aa)
GRAMD2GRAM domain-containing protein 2 isoform A. (329 aa)
Y1Q_0017822Tyrosine-protein kinase. (574 aa)
NPHS2Podocin. (385 aa)
RGS8Regulator of G-protein signaling 8. (298 aa)
RGS1Regulator of G-protein signaling 1. (185 aa)
HCKTyrosine-protein kinase. (555 aa)
Y1Q_0011868Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (125 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
TRAF1-1TNF receptor-associated factor 1 isoform C. (723 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (601 aa)
GNB3WD_REPEATS_REGION domain-containing protein. (340 aa)
THBH4_AAA_HYDROXYL_2 domain-containing protein. (531 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (576 aa)
MYZAPMyocardial zonula adherens protein. (479 aa)
Y1Q_0001438Uncharacterized protein. (67 aa)
MDP1Magnesium-dependent phosphatase 1. (160 aa)
PGM1Phosphoglucomutase-1. (567 aa)
Y1Q_0012624Uncharacterized protein. (354 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (333 aa)
SYK-2Tyrosine-protein kinase. (608 aa)
CBY3Chibby-like protein 3. (161 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
SRCTyrosine-protein kinase. (590 aa)
FRKTyrosine-protein kinase. (544 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (87 aa)
EZRFERM domain-containing protein. (561 aa)
SNX9Sorting nexin. (600 aa)
AKAP5A-kinase anchor protein 5. (488 aa)
Y1Q_0006941Tyrosine-protein kinase STYK1-like. (354 aa)
PTPN4Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (953 aa)
ESYT3Extended synaptotagmin-3 isoform C. (775 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (114 aa)
ASPSCR1Tether containing UBX domain for GLUT4 isoform A. (536 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (453 aa)
CYLDLUbiquitin carboxyl-terminal hydrolase CYLD-like; Belongs to the peptidase C19 family. (788 aa)
PTPN3Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (939 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (158 aa)
SHROOM4Protein Shroom4. (1579 aa)
MTSS1Metastasis suppressor protein 1 isoform B. (788 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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