STRINGSTRING
SPINT1 SPINT1 RNF112 RNF112 IL6ST IL6ST RNF112L RNF112L SOX8 SOX8 Y1Q_0006003 Y1Q_0006003 MTOR MTOR LIF LIF TENM4 TENM4 ASPA ASPA SERPINE2 SERPINE2 SLC7A5 SLC7A5 PTN PTN IL34 IL34 TNF TNF UFL1 UFL1 NKX6-2 NKX6-2 TGFB1 TGFB1 MAG MAG VEGFC VEGFC GFAP GFAP PTPRZ1 PTPRZ1 TNFRSF1B TNFRSF1B NKX6-1 NKX6-1 MDK MDK SYNJ1 SYNJ1 IL1BL IL1BL Y1Q_0001844 Y1Q_0001844 LYN LYN IL6 IL6 ACY3 ACY3 CLCF1 CLCF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPINT1Kunitz-type protease inhibitor 1. (473 aa)
RNF112RING finger protein 112. (640 aa)
IL6STInterleukin-6 receptor subunit beta. (854 aa)
RNF112LRING finger protein 112. (527 aa)
SOX8Transcription factor SOX-8. (471 aa)
Y1Q_0006003Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (688 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
LIFLeukemia inhibitory factor. (211 aa)
TENM4Uncharacterized protein. (2883 aa)
ASPAAspartoacylase. (328 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (428 aa)
SLC7A5Large neutral amino acids transporter small subunit 1. (511 aa)
PTNPleiotrophin. (165 aa)
IL34Interleukin-34 isoform B. (247 aa)
TNFTumor necrosis factor. (231 aa)
UFL1E3 UFM1-protein ligase 1. (793 aa)
NKX6-2Homeobox protein Nkx-6.2. (154 aa)
TGFB1TGF_BETA_2 domain-containing protein. (242 aa)
MAGMyelin-associated glycoprotein. (663 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (414 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (447 aa)
PTPRZ1Protein-tyrosine-phosphatase. (1295 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B. (467 aa)
NKX6-1Homeobox protein Nkx-6.1. (336 aa)
MDKMidkine. (156 aa)
SYNJ1PAX3-and PAX7-binding protein 1. (2276 aa)
IL1BLInterleukin-1. (280 aa)
Y1Q_0001844Interleukin-1. (129 aa)
LYNTyrosine-protein kinase. (562 aa)
IL6Interleukin-6. (178 aa)
ACY3N-acyl-aromatic-L-amino acid amidohydrolase (Carboxylate-forming). (316 aa)
CLCF1Cardiotrophin-like cytokine factor 1. (232 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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