(20 nodes) Hexosaminidase activity network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HYAL1	Hyaluronidase. (445 aa)
	TMEM2	Transmembrane protein 2. (1374 aa)
	HYAL4	Hyaluronidase. (507 aa)
	SPAM1-1	Hyaluronidase. (464 aa)
	HEXB-2	Uncharacterized protein. (441 aa)
	HYAL3-1	Hyaluronidase. (644 aa)
	HEXB	Beta-hexosaminidase. (531 aa)
	Y1Q_0016678	Uncharacterized protein. (159 aa)
	Y1Q_0008184	Uncharacterized protein. (68 aa)
	HEXDC	Hexosaminidase D. (472 aa)
	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (451 aa)
	NAGA	Alpha-galactosidase. (511 aa)
	GM2A	Ganglioside GM2 activator. (191 aa)
	MGEA5	Protein O-GlcNAcase. (841 aa)
	Y1Q_0019906	Protein O-GlcNAcase-like. (522 aa)
	HEXDCL	Hexosaminidase D. (661 aa)
	FAM149B1	Protein FAM149B1. (596 aa)
	HYAL2	Hyaluronidase. (474 aa)
	FAM149A	Protein FAM149A. (613 aa)
	HYAL6	Hyaluronidase. (454 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM149A	GM2A	A0A151PAG9	A0A151NL85	Protein FAM149A.	Ganglioside GM2 activator.	0.588
FAM149B1	GM2A	A0A151NZT3	A0A151NL85	Protein FAM149B1.	Ganglioside GM2 activator.	0.588
GM2A	FAM149A	A0A151NL85	A0A151PAG9	Ganglioside GM2 activator.	Protein FAM149A.	0.588
GM2A	FAM149B1	A0A151NL85	A0A151NZT3	Ganglioside GM2 activator.	Protein FAM149B1.	0.588
GM2A	HEXB	A0A151NL85	A0A151ML73	Ganglioside GM2 activator.	Beta-hexosaminidase.	0.841
GM2A	HEXB-2	A0A151NL85	A0A151PHJ1	Ganglioside GM2 activator.	Uncharacterized protein.	0.792
HEXB	GM2A	A0A151ML73	A0A151NL85	Beta-hexosaminidase.	Ganglioside GM2 activator.	0.841
HEXB	HEXB-2	A0A151ML73	A0A151PHJ1	Beta-hexosaminidase.	Uncharacterized protein.	0.994
HEXB	HEXDC	A0A151ML73	A0A151N357	Beta-hexosaminidase.	Hexosaminidase D.	0.930
HEXB	HEXDCL	A0A151ML73	A0A151NXG4	Beta-hexosaminidase.	Hexosaminidase D.	0.927
HEXB	NAGA	A0A151ML73	A0A151NHD5	Beta-hexosaminidase.	Alpha-galactosidase.	0.973
HEXB-2	GM2A	A0A151PHJ1	A0A151NL85	Uncharacterized protein.	Ganglioside GM2 activator.	0.792
HEXB-2	HEXB	A0A151PHJ1	A0A151ML73	Uncharacterized protein.	Beta-hexosaminidase.	0.994
HEXB-2	HEXDC	A0A151PHJ1	A0A151N357	Uncharacterized protein.	Hexosaminidase D.	0.927
HEXB-2	HEXDCL	A0A151PHJ1	A0A151NXG4	Uncharacterized protein.	Hexosaminidase D.	0.927
HEXB-2	NAGA	A0A151PHJ1	A0A151NHD5	Uncharacterized protein.	Alpha-galactosidase.	0.921
HEXDC	HEXB	A0A151N357	A0A151ML73	Hexosaminidase D.	Beta-hexosaminidase.	0.930
HEXDC	HEXB-2	A0A151N357	A0A151PHJ1	Hexosaminidase D.	Uncharacterized protein.	0.927
HEXDC	HEXDCL	A0A151N357	A0A151NXG4	Hexosaminidase D.	Hexosaminidase D.	0.903
HEXDC	HYAL2	A0A151N357	A0A151MEK7	Hexosaminidase D.	Hyaluronidase.	0.470