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GPD2 GPD2 PYGB-2 PYGB-2 GALM GALM AGL AGL Y1Q_0005850 Y1Q_0005850 IDNK IDNK MAN2C1 MAN2C1 SORD SORD MPPED2-2 MPPED2-2 GAPDH GAPDH ENO2-2 ENO2-2 TPI1 TPI1 ABHD10 ABHD10 HTR2A HTR2A NEU4 NEU4 ADPGK ADPGK NEU1 NEU1 ALDOA ALDOA PGAM2 PGAM2 OGDHL OGDHL GALE GALE STBD1 STBD1 RB1CC1 RB1CC1 OGDHL-2 OGDHL-2 PGAM1 PGAM1 TP53 TP53 ENO2 ENO2 Y1Q_0008184 Y1Q_0008184 FOXK1 FOXK1 GALK1 GALK1 PYGL PYGL PGD PGD ENO1 ENO1 MIOX MIOX GUSB GUSB MPPED1 MPPED1 GPI GPI GK5 GK5 MGAM MGAM ALDOC ALDOC ENOSF1 ENOSF1 PYGB PYGB Y1Q_0015294 Y1Q_0015294 NAGA NAGA PFKP PFKP BPGM BPGM DERA DERA ALDOC-2 ALDOC-2 Y1Q_0008427 Y1Q_0008427 DHDH DHDH GM2A GM2A PGK1 PGK1 Y1Q_0023325 Y1Q_0023325 SEC61A1 SEC61A1 TIGAR TIGAR GCK GCK PFKM PFKM RBKS RBKS AOAH AOAH HK1 HK1 HKDC1 HKDC1 TKFC TKFC LRP5 LRP5 GCK-2 GCK-2 NEU3 NEU3 HEXB-2 HEXB-2 Y1Q_0014478 Y1Q_0014478 NUDT5 NUDT5 GK GK ENO4 ENO4 NEU2 NEU2 FOXK2 FOXK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (745 aa)
PYGB-2Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (853 aa)
GALMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (341 aa)
AGLGlycogen debranching enzyme isoform A. (2015 aa)
Y1Q_0005850Glyceraldehyde-3-phosphate dehydrogenase. (394 aa)
IDNKGluconokinase; Belongs to the gluconokinase GntK/GntV family. (184 aa)
MAN2C1Alpha-mannosidase 2C1. (1018 aa)
SORDSorbitol dehydrogenase. (348 aa)
MPPED2-2Metallophosphoesterase domain-containing 2b. (347 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
ENO2-2Uncharacterized protein. (849 aa)
TPI1Triosephosphate isomerase. (248 aa)
ABHD10Transgelin; Belongs to the calponin family. (487 aa)
HTR2A5-hydroxytryptamine receptor 2A; Belongs to the G-protein coupled receptor 1 family. (489 aa)
NEU4Sialidase-4. (532 aa)
ADPGKADP-dependent glucokinase isoform A. (432 aa)
NEU1Sialidase-1. (242 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
OGDHL2-oxoglutarate dehydrogenase-like, mitochondrial isoform B. (967 aa)
GALEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (347 aa)
STBD1Starch-binding domain-containing protein 1. (359 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform A. (1595 aa)
OGDHL-2Transket_pyr domain-containing protein. (1086 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
ENO2Gamma-enolase. (386 aa)
Y1Q_0008184Uncharacterized protein. (68 aa)
FOXK1Forkhead box protein K1. (598 aa)
GALK1Galactokinase. (393 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (864 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family. (637 aa)
ENO1Uncharacterized protein. (470 aa)
MIOXInositol oxygenase. (281 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (644 aa)
MPPED1Metallophosphoesterase MPPED2. (302 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
GK5Putative glycerol kinase 5 isoform A; Belongs to the FGGY kinase family. (560 aa)
MGAMUncharacterized protein. (1834 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (708 aa)
ENOSF1Mitochondrial enolase superfamily member 1. (446 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
Y1Q_0015294Uncharacterized protein. (946 aa)
NAGAAlpha-galactosidase. (511 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (781 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (260 aa)
DERADeoxyribose-phosphate aldolase. (318 aa)
ALDOC-2Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (357 aa)
Y1Q_0008427Uncharacterized protein. (126 aa)
DHDHTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (340 aa)
GM2AGanglioside GM2 activator. (191 aa)
PGK1Phosphoglycerate kinase. (417 aa)
Y1Q_0023325Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (929 aa)
SEC61A1Protein transport protein Sec61 subunit alpha. (1366 aa)
TIGARFructose-2,6-bisphosphatase TIGAR. (272 aa)
GCKGlucokinase isoform A. (913 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (841 aa)
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (308 aa)
AOAHAcyloxyacyl hydrolase isoform B. (638 aa)
HK1Uncharacterized protein. (917 aa)
HKDC1Uncharacterized protein. (940 aa)
TKFCTriokinase/FMN cyclase. (579 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1594 aa)
GCK-2Phosphotransferase. (465 aa)
NEU3Sialidase-3. (451 aa)
HEXB-2Uncharacterized protein. (441 aa)
Y1Q_0014478ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (838 aa)
NUDT5ADP-sugar pyrophosphatase; Belongs to the Nudix hydrolase family. (220 aa)
GKGlycerol kinase; Belongs to the FGGY kinase family. (526 aa)
ENO4Enolase-like protein ENO4. (573 aa)
NEU2Sialidase-2. (423 aa)
FOXK2Forkhead box protein K2. (562 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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