73 items (Alligator mississippiensis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNX4	Sorting nexin-4 isoform A. (423 aa)
	DCN	Decorin; May affect the rate of fibrils formation. (320 aa)
	PAFAH1B2	Platelet-activating factor acetylhydrolase IB subunit beta. (243 aa)
	RAB3GAP1	Rab3 GTPase-activating protein catalytic subunit. (1012 aa)
	ATG14	Beclin 1-associated autophagy-related key regulator. (497 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (527 aa)
	SNX7	Sorting nexin-7. (431 aa)
	SPTLC1	Serine palmitoyltransferase 1. (470 aa)
	AMBRA1	Activating molecule in BECN1-regulated autophagy protein 1 isoform A. (1224 aa)
	LARP1B-1	La-related protein 1B. (959 aa)
	LRSAM1	E3 ubiquitin-protein ligase LRSAM1. (728 aa)
	TSC1	Hamartin isoform B. (1115 aa)
	GPSM1	TPR_REGION domain-containing protein. (675 aa)
	FEZ2	Fasciculation and elongation protein zeta-2. (253 aa)
	ATP13A2-2	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1482 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the arginase family. (851 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	SESN1-2	Uncharacterized protein. (481 aa)
	TBC1D25	TBC1 domain family member 25. (458 aa)
	RIPK3L	Receptor-interacting serine/threonine-protein kinase 2. (564 aa)
	TMEM39B	Transmembrane protein 39B. (459 aa)
	PHF23-2	PHD finger protein 23. (71 aa)
	NOD1	Nucleotide-binding oligomerization domain-containing protein 1. (951 aa)
	ATG2A	Uncharacterized protein. (1912 aa)
	NRBP2	Nuclear receptor-binding protein 2. (525 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
	RUBCN	Run domain Beclin-1 interacting and cysteine-rich containing protein isoform A. (1001 aa)
	CLEC16A	Protein CLEC16A isoform D. (1085 aa)
	SMG1	Serine/threonine-protein kinase SMG1 isoform A; Belongs to the PI3/PI4-kinase family. (3628 aa)
	SMCR8	Smith-Magenis syndrome chromosomal region candidate 8 protein. (935 aa)
	TSC2	Tuberin isoform D. (1829 aa)
	SUPT5H	Transcription elongation factor SPT5 isoform A. (1259 aa)
	WIPI1	WD repeat domain phosphoinositide-interacting protein 1. (443 aa)
	MTOR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
	WDR24	WD repeat-containing protein 24. (937 aa)
	FEZ1	Fasciculation and elongation protein zeta-1 isoform A. (451 aa)
	PHF23-1	PHD finger protein 23. (297 aa)
	LZTS1	Leucine zipper putative tumor suppressor 1. (613 aa)
	SNX30	Sorting nexin-30 isoform B. (413 aa)
	SESN2L	Sestrin 2. (509 aa)
	POLDIP2	Polymerase delta-interacting protein 2. (331 aa)
	SCOC	Short coiled-coil protein. (84 aa)
	SCFD1	Sec1 family domain-containing protein 1; Belongs to the STXBP/unc-18/SEC1 family. (632 aa)
	EPM2A	Laforin. (305 aa)
	RNF31	E3 ubiquitin-protein ligase RNF31. (955 aa)
	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2. (2528 aa)
	TMEM173	Stimulator of interferon genes protein. (403 aa)
	ULK1A	Unc-51 like autophagy activating kinase 1a isoform A. (1048 aa)
	SEC22B	Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family. (188 aa)
	BAG3	BAG family molecular chaperone regulator 3. (552 aa)
	SESN2	Sestrin-3-like. (447 aa)
	CLN3	Battenin. (460 aa)
	Y1Q_0004499	Uncharacterized protein. (568 aa)
	SIRT1	NAD-dependent protein deacetylase sirtuin-1. (634 aa)
	SESN1	Sestrin-1. (559 aa)
	RNF41	E3 ubiquitin-protein ligase NRDP1. (261 aa)
	FYCO1	FYVE and coiled-coil domain-containing protein 1. (1545 aa)
	RUFY4	RUN and FYVE domain-containing protein 4. (260 aa)
	PIK3R4	Phosphoinositide 3-kinase regulatory subunit 4. (1397 aa)
	RAB3GAP2	Rab3 GTPase-activating protein non-catalytic subunit isoform C. (1382 aa)
	BNIP3	BCL2/adenovirus E1B protein-interacting protein 3. (200 aa)
	PIP4K2B	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (411 aa)
	CALCOCO2	Calcium-binding and coiled-coil domain-containing protein 2 isoform B. (583 aa)
	TIGAR	Fructose-2,6-bisphosphatase TIGAR. (272 aa)
	HTT	Huntingtin isoform A. (3112 aa)
	KDR	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1353 aa)
	WAC	WW domain-containing adapter protein with coiled-coil isoform B. (617 aa)
	PIP4K2A	PIPK domain-containing protein. (405 aa)
	PIP4K2C	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (458 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2. (561 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (150 aa)
	VPS13D	Vacuolar protein sorting-associated protein 13D isoform C. (4216 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBRA1	ATG12	A0A151MB96	A0A151PIF5	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.559
AMBRA1	ATG14	A0A151MB96	A0A151M1Z6	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	Beclin 1-associated autophagy-related key regulator.	0.825
AMBRA1	ATG5	A0A151MB96	A0A151MJF5	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.542
AMBRA1	PIK3C3	A0A151MB96	A0A151MWA8	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.880
AMBRA1	PIK3R4	A0A151MB96	A0A151P307	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	Phosphoinositide 3-kinase regulatory subunit 4.	0.889
AMBRA1	PRKAA1	A0A151MB96	A0A151M4H2	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	Non-specific serine/threonine protein kinase.	0.447
AMBRA1	RUBCN	A0A151MB96	A0A151MZA9	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	Run domain Beclin-1 interacting and cysteine-rich containing protein isoform A.	0.494
AMBRA1	ULK1A	A0A151MB96	A0A151NRZ2	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	Unc-51 like autophagy activating kinase 1a isoform A.	0.760
AMBRA1	WIPI1	A0A151MB96	A0A151N2G4	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	WD repeat domain phosphoinositide-interacting protein 1.	0.401
ATG12	AMBRA1	A0A151PIF5	A0A151MB96	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Activating molecule in BECN1-regulated autophagy protein 1 isoform A.	0.559
ATG12	ATG14	A0A151PIF5	A0A151M1Z6	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Beclin 1-associated autophagy-related key regulator.	0.921
ATG12	ATG2A	A0A151PIF5	A0A151MUE5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.538
ATG12	ATG5	A0A151PIF5	A0A151MJF5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	BNIP3	A0A151PIF5	A0A151P4M6	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	BCL2/adenovirus E1B protein-interacting protein 3.	0.584
ATG12	MTOR	A0A151PIF5	A0A151N3S4	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.582
ATG12	PIK3C3	A0A151PIF5	A0A151MWA8	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.890
ATG12	PIK3R4	A0A151PIF5	A0A151P307	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Phosphoinositide 3-kinase regulatory subunit 4.	0.887
ATG12	PINK1	A0A151PIF5	A0A151MJ81	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the arginase family.	0.736
ATG12	SNX30	A0A151PIF5	A0A151NEA0	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Sorting nexin-30 isoform B.	0.422
ATG12	SNX7	A0A151PIF5	A0A151M559	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Sorting nexin-7.	0.422