STRINGSTRING
EDEM1 EDEM1 MBD4 MBD4 ADPRHL ADPRHL NEU3 NEU3 MAN2A1-2 MAN2A1-2 HEXB-2 HEXB-2 MUTYH MUTYH ADPRHL2 ADPRHL2 LYZ LYZ SPAM1-1 SPAM1-1 EDEM3 EDEM3 MACROD2 MACROD2 MACROD2L MACROD2L Y1Q_0002346 Y1Q_0002346 AMY2A AMY2A Y1Q_0010113 Y1Q_0010113 Y1Q_0005598 Y1Q_0005598 TLR4 TLR4 MAN1B1 MAN1B1 HYAL4 HYAL4 HYAL6 HYAL6 LYZL1 LYZL1 NEIL3 NEIL3 FAM149A FAM149A GBA3 GBA3 BST1-1 BST1-1 Y1Q_0021522 Y1Q_0021522 MAN1C1 MAN1C1 FUCA1 FUCA1 KLB KLB GBA2 GBA2 PARG PARG GANC GANC NEIL2 NEIL2 MOGS MOGS ENGASE ENGASE Y1Q_0000005 Y1Q_0000005 Y1Q_0000003 Y1Q_0000003 Y1Q_0017145 Y1Q_0017145 TMEM130 TMEM130 Y1Q_0008184 Y1Q_0008184 NTHL1 NTHL1 HEXDC HEXDC NEU4 NEU4 Y1Q_0008563 Y1Q_0008563 GUSB GUSB NAGPA NAGPA GBA GBA MGAM MGAM MAN2B1 MAN2B1 GNE GNE Y1Q_0000948 Y1Q_0000948 IDUA IDUA Y1Q_0013819 Y1Q_0013819 Y1Q_0020688 Y1Q_0020688 NAGA NAGA TDG TDG Y1Q_0024232 Y1Q_0024232 GM2A GM2A MACROD1 MACROD1 CLN5 CLN5 FUCA2 FUCA2 MANBA MANBA GLA GLA IL1RAPL2 IL1RAPL2 Y1Q_0023325 Y1Q_0023325 MGEA5 MGEA5 GLB1L2 GLB1L2 Y1Q_0019906 Y1Q_0019906 UNG UNG MANEA MANEA TLR2A TLR2A IL1RAPL1 IL1RAPL1 Y1Q_0000053 Y1Q_0000053 NEU2 NEU2 SARM1 SARM1 ACER1 ACER1 IL1RL1-1 IL1RL1-1 IL1R1 IL1R1 HEXDCL HEXDCL ADPRHL1 ADPRHL1 TMEM258 TMEM258 MAN2A1 MAN2A1 GANAB GANAB ATHL1 ATHL1 FAM149B1 FAM149B1 HPSE HPSE Y1Q_0016123 Y1Q_0016123 Y1Q_0016122 Y1Q_0016122 GLB1-2 GLB1-2 Y1Q_0020709 Y1Q_0020709 OARD1 OARD1 SMUG1 SMUG1 PCNA PCNA HPSE2-1 HPSE2-1 HYAL3-1 HYAL3-1 HYAL2 HYAL2 HYAL1 HYAL1 GBE1 GBE1 ADPRH-1 ADPRH-1 ABHD10 ABHD10 OTOG OTOG Y1Q_0000710 Y1Q_0000710 MAN2C1 MAN2C1 NEIL1 NEIL1 LCTL LCTL TMEM2 TMEM2 AGL AGL ACER3 ACER3 MAN1A2 MAN1A2 MAN1A2-2 MAN1A2-2 LCT LCT HPSE2-2 HPSE2-2 GLB1 GLB1 SMPD1 SMPD1 MPG MPG MAN2B2 MAN2B2 GALC GALC HEXB HEXB NEU1 NEU1 IL1RAP-1 IL1RAP-1 Y1Q_0016678 Y1Q_0016678
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (516 aa)
MBD4Methyl-CpG-binding domain protein 4. (565 aa)
ADPRHLProtein ADP-ribosylarginine hydrolase. (350 aa)
NEU3Sialidase-3. (451 aa)
MAN2A1-2Alpha-mannosidase. (1153 aa)
HEXB-2Uncharacterized protein. (441 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (505 aa)
ADPRHL2Poly(ADP-ribose) glycohydrolase ARH3. (311 aa)
LYZLysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family. (138 aa)
SPAM1-1Hyaluronidase. (464 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (857 aa)
MACROD2O-acetyl-ADP-ribose deacetylase MACROD2. (275 aa)
MACROD2LO-acetyl-ADP-ribose deacetylase MACROD2 isoform C. (121 aa)
Y1Q_0002346O-acetyl-ADP-ribose deacetylase MACROD2-like. (94 aa)
AMY2AAlpha-amylase. (480 aa)
Y1Q_0010113Alpha-amylase. (717 aa)
Y1Q_0005598alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (822 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
MAN1B1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (668 aa)
HYAL4Hyaluronidase. (507 aa)
HYAL6Hyaluronidase. (454 aa)
LYZL1Lysozyme-like protein 1; Belongs to the glycosyl hydrolase 22 family. (220 aa)
NEIL3Endonuclease 8-like 3. (508 aa)
FAM149AProtein FAM149A. (613 aa)
GBA3Cytosolic beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (118 aa)
BST1-1ADP-ribosyl cyclase 2 isoform C. (339 aa)
Y1Q_0021522Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (556 aa)
MAN1C1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (473 aa)
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (452 aa)
KLBBeta-klotho isoform A; Belongs to the glycosyl hydrolase 1 family. (724 aa)
GBA2Non-lysosomal glucosylceramidase. (597 aa)
PARGPoly(ADP-ribose) glycohydrolase. (928 aa)
GANCNeutral alpha-glucosidase C; Belongs to the glycosyl hydrolase 31 family. (882 aa)
NEIL2Endonuclease 8-like 2. (300 aa)
MOGSMannosyl-oligosaccharide glucosidase. (369 aa)
ENGASECytosolic endo-beta-N-acetylglucosaminidase. (922 aa)
Y1Q_0000005TIR domain-containing protein. (222 aa)
Y1Q_0000003TIR domain-containing protein. (145 aa)
Y1Q_0017145Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (482 aa)
TMEM130Transmembrane protein 130. (487 aa)
Y1Q_0008184Uncharacterized protein. (68 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (377 aa)
HEXDCHexosaminidase D. (472 aa)
NEU4Sialidase-4. (532 aa)
Y1Q_0008563Uncharacterized protein. (112 aa)
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (644 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (451 aa)
GBAGlucosylceramidase. (779 aa)
MGAMUncharacterized protein. (1834 aa)
MAN2B1Alpha-mannosidase. (985 aa)
GNEBifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase. (722 aa)
Y1Q_0000948Uncharacterized protein. (96 aa)
IDUAAlpha-L-iduronidase. (549 aa)
Y1Q_0013819Uncharacterized protein. (169 aa)
Y1Q_0020688Glucosylceramidase. (347 aa)
NAGAAlpha-galactosidase. (511 aa)
TDGG/T mismatch-specific thymine DNA glycosylase. (404 aa)
Y1Q_0024232Pseudouridine-5'-phosphate glycosidase-like. (721 aa)
GM2AGanglioside GM2 activator. (191 aa)
MACROD1O-acetyl-ADP-ribose deacetylase MACROD1. (96 aa)
CLN5Ceroid-lipofuscinosis neuronal protein 5. (335 aa)
FUCA2Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (453 aa)
MANBABeta-mannosidase; Belongs to the ubiquitin-conjugating enzyme family. (1003 aa)
GLAAlpha-galactosidase. (431 aa)
IL1RAPL2X-linked interleukin-1 receptor accessory protein-like 2 isoform A. (593 aa)
Y1Q_0023325Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (929 aa)
MGEA5Protein O-GlcNAcase. (841 aa)
GLB1L2Beta-galactosidase. (635 aa)
Y1Q_0019906Protein O-GlcNAcase-like. (522 aa)
UNGUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (301 aa)
MANEAGlycoprotein endo-alpha-1,2-mannosidase. (280 aa)
TLR2AToll-like receptor 2 type-1; Belongs to the Toll-like receptor family. (801 aa)
IL1RAPL1TIR domain-containing protein. (213 aa)
Y1Q_0000053Ig-like domain-containing protein. (196 aa)
NEU2Sialidase-2. (423 aa)
SARM1Sterile alpha and TIR motif-containing protein 1. (716 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (318 aa)
IL1RL1-1Interleukin-1 receptor-like 1 isoform A. (548 aa)
IL1R1Interleukin-1 receptor type 1. (1039 aa)
HEXDCLHexosaminidase D. (661 aa)
ADPRHL1Protein ADP-ribosylarginine hydrolase-like protein 1. (1704 aa)
TMEM258Transmembrane protein 258. (70 aa)
MAN2A1Alpha-mannosidase. (1161 aa)
GANABUncharacterized protein. (280 aa)
ATHL1Acid trehalase-like protein 1. (628 aa)
FAM149B1Protein FAM149B1. (596 aa)
HPSEHeparanase. (529 aa)
Y1Q_0016123Uncharacterized protein. (157 aa)
Y1Q_0016122Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (80 aa)
GLB1-2Beta-galactosidase. (651 aa)
Y1Q_0020709Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (229 aa)
OARD1O-acetyl-ADP-ribose deacetylase 1. (151 aa)
SMUG1Single-strand selective monofunctional uracil DNA glycosylase. (220 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
HPSE2-1Inactive heparanase-2. (324 aa)
HYAL3-1Hyaluronidase. (644 aa)
HYAL2Hyaluronidase. (474 aa)
HYAL1Hyaluronidase. (445 aa)
GBE11,4-alpha-glucan-branching enzyme. (652 aa)
ADPRH-1ADP-ribosylarginine hydrolase isoform B. (310 aa)
ABHD10Transgelin; Belongs to the calponin family. (487 aa)
OTOGUncharacterized protein. (1061 aa)
Y1Q_0000710Uncharacterized protein. (1261 aa)
MAN2C1Alpha-mannosidase 2C1. (1018 aa)
NEIL1Endonuclease 8-like 1. (437 aa)
LCTLLactase-like protein; Belongs to the glycosyl hydrolase 1 family. (568 aa)
TMEM2Transmembrane protein 2. (1374 aa)
AGLGlycogen debranching enzyme isoform A. (2015 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
MAN1A2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (537 aa)
MAN1A2-2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (643 aa)
LCTLactase-phlorizin hydrolase. (1720 aa)
HPSE2-2Inactive heparanase-2. (299 aa)
GLB1Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family. (569 aa)
SMPD1Sphingomyelin phosphodiesterase. (287 aa)
MPGDNA-3-methyladenine glycosylase. (308 aa)
MAN2B2Alpha-mannosidase. (1006 aa)
GALCGalactocerebrosidase isoform C. (637 aa)
HEXBBeta-hexosaminidase. (531 aa)
NEU1Sialidase-1. (242 aa)
IL1RAP-1Interleukin-1 receptor accessory protein isoform B. (852 aa)
Y1Q_0016678Uncharacterized protein. (159 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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