(34 nodes) Lipid storage network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL1BL	Interleukin-1. (280 aa)
	Y1Q_0011595	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
	CDS2	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (443 aa)
	FITM1	Fat storage-inducing transmembrane protein 1. (278 aa)
	AUP1	Ancient ubiquitous protein 1. (369 aa)
	CRY2-2	Photolyase/cryptochrome alpha/beta domain-containing protein. (547 aa)
	LRRN4CL	LRRN4 C-terminal-like protein. (261 aa)
	NRIP1	Nuclear receptor-interacting protein 1. (391 aa)
	PLA2G4C	Cytosolic phospholipase A2 gamma. (499 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	HEXB	Beta-hexosaminidase. (531 aa)
	Y1Q_0005880	Free fatty acid receptor 2-like; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	Y1Q_0005879	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (322 aa)
	Y1Q_0001844	Interleukin-1. (129 aa)
	ZFYVE1	Zinc finger FYVE domain-containing protein 1. (697 aa)
	TMEM159	Promethin. (157 aa)
	B4GALNT1	Beta-1,4 N-acetylgalactosaminyltransferase. (537 aa)
	PNPLA3	Patatin-like phospholipase domain-containing protein 2 isoform B. (530 aa)
	BSCL2	Seipin. (353 aa)
	CRY1	Cryptochrome 4. (665 aa)
	GM2A	Ganglioside GM2 activator. (191 aa)
	CD36	Platelet glycoprotein 4; Belongs to the CD36 family. (461 aa)
	TNF	Tumor necrosis factor. (231 aa)
	Y1Q_0004461	Uncharacterized protein. (333 aa)
	FFAR2	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (322 aa)
	PNPLA2	Patatin-like phospholipase domain-containing protein 2. (483 aa)
	PLIN2	Perilipin; Belongs to the perilipin family. (516 aa)
	Y1Q_0015233	PLA2c domain-containing protein. (130 aa)
	CDS2-2	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (444 aa)
	SQLE	Squalene monooxygenase. (560 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	HEXB-2	Uncharacterized protein. (441 aa)
	STARD4	StAR-related lipid transfer protein 4. (233 aa)
	LDAH-1	Lipid droplet-associated hydrolase isoform B. (338 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B4GALNT1	HEXB	A0A151N3A4	A0A151ML73	Beta-1,4 N-acetylgalactosaminyltransferase.	Beta-hexosaminidase.	0.934
B4GALNT1	HEXB-2	A0A151N3A4	A0A151PHJ1	Beta-1,4 N-acetylgalactosaminyltransferase.	Uncharacterized protein.	0.924
BSCL2	TMEM159	A0A151NC92	A0A151N1T9	Seipin.	Promethin.	0.405
CAV1	CAV3	A0A151PF23	A0A151MKB4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV1	CD36	A0A151PF23	A0A151NPC0	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.469
CAV3	CAV1	A0A151MKB4	A0A151PF23	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV3	CD36	A0A151MKB4	A0A151NPC0	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.469
CD36	CAV1	A0A151NPC0	A0A151PF23	Platelet glycoprotein 4; Belongs to the CD36 family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.469
CD36	CAV3	A0A151NPC0	A0A151MKB4	Platelet glycoprotein 4; Belongs to the CD36 family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.469
CD36	PLIN2	A0A151NPC0	A0A151P2P1	Platelet glycoprotein 4; Belongs to the CD36 family.	Perilipin; Belongs to the perilipin family.	0.419
CD36	Y1Q_0004461	A0A151NPC0	A0A151NSW7	Platelet glycoprotein 4; Belongs to the CD36 family.	Uncharacterized protein.	0.419
CDS2	CDS2-2	A0A151M425	A0A151P654	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	0.901
CDS2-2	CDS2	A0A151P654	A0A151M425	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin.	0.901
CRY1	CRY2-2	A0A151NHX9	A0A151MB79	Cryptochrome 4.	Photolyase/cryptochrome alpha/beta domain-containing protein.	0.955
CRY2-2	CRY1	A0A151MB79	A0A151NHX9	Photolyase/cryptochrome alpha/beta domain-containing protein.	Cryptochrome 4.	0.955
GM2A	HEXB	A0A151NL85	A0A151ML73	Ganglioside GM2 activator.	Beta-hexosaminidase.	0.841
GM2A	HEXB-2	A0A151NL85	A0A151PHJ1	Ganglioside GM2 activator.	Uncharacterized protein.	0.792
HEXB	B4GALNT1	A0A151ML73	A0A151N3A4	Beta-hexosaminidase.	Beta-1,4 N-acetylgalactosaminyltransferase.	0.934
HEXB	GM2A	A0A151ML73	A0A151NL85	Beta-hexosaminidase.	Ganglioside GM2 activator.	0.841
HEXB	HEXB-2	A0A151ML73	A0A151PHJ1	Beta-hexosaminidase.	Uncharacterized protein.	0.994