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EIF3M EIF3M EIF3H EIF3H EIF3E EIF3E TRAF7 TRAF7 GLTSCR2 GLTSCR2 ISY1 ISY1 PRPF6 PRPF6 ZRSR2 ZRSR2 EIF2S3 EIF2S3 GEMIN8 GEMIN8 Y1Q_0016140 Y1Q_0016140 Y1Q_0008192 Y1Q_0008192 EIF3B EIF3B PRMT5 PRMT5 LUC7L3-1 LUC7L3-1 COIL COIL MRPS7 MRPS7 Y1Q_0009070 Y1Q_0009070 MRPL20 MRPL20 SNRPD3 SNRPD3 RPLP0 RPLP0 SF3A1 SF3A1 CLNS1A CLNS1A EIF4H EIF4H ZNHIT3 ZNHIT3 Y1Q_0000382 Y1Q_0000382 BOP1 BOP1 ERAL1 ERAL1 SRPK2 SRPK2 DHX30 DHX30 FASTKD2 FASTKD2 SF3B1 SF3B1 GEMIN4 GEMIN4 NLE1 NLE1 SNRPE SNRPE CRNKL1 CRNKL1 SRPK3-1 SRPK3-1 PIH1D2 PIH1D2 SF3A3 SF3A3 SHD SHD SF3A2 SF3A2 LUC7L-1 LUC7L-1 EIF3L EIF3L SNU13 SNU13 CUNH12orf45 CUNH12orf45 EIF3D EIF3D STRAP STRAP ZNHIT6 ZNHIT6 PIH1D1 PIH1D1 RUVBL2 RUVBL2 GEMIN2 GEMIN2 CDC73 CDC73 MCTS1 MCTS1 PRPF8 PRPF8 Y1Q_0006637 Y1Q_0006637 PRPF18 PRPF18 Y1Q_0023357 Y1Q_0023357 ABT1 ABT1 CELF2 CELF2 Y1Q_0005435 Y1Q_0005435 PWP2 PWP2 SFSWAP SFSWAP SART3 SART3 DENR DENR RPL6 RPL6 USP39 USP39 CLP1 CLP1 EIF3A EIF3A EIF6 EIF6 RPL38 RPL38 CCDC94 CCDC94 EIF3C EIF3C CPSF7 CPSF7 PRPF19 PRPF19 SNRPC SNRPC CELF5 CELF5 PSIP1 PSIP1 RPSA RPSA SNRPD1 SNRPD1 SNRPG SNRPG EIF3K EIF3K AGO2 AGO2 EIF5 EIF5 DICER1 DICER1 NAF1 NAF1 PTGES3 PTGES3 PRPF39 PRPF39 Y1Q_0013170 Y1Q_0013170 SCAF11 SCAF11 CPSF6 CPSF6 EIF3G EIF3G RPS15 RPS15 XAB2 XAB2 AGO1 AGO1 EIF2C4 EIF2C4 EIF2C3 EIF2C3 SMN SMN SNRPF SNRPF RPS27 RPS27 CCDC105 CCDC105 RPS5 RPS5 PRMT7 PRMT7 LSM4 LSM4 BOP1L BOP1L CELF6 CELF6 SHQ1 SHQ1 SNRPD2 SNRPD2 RUVBL1 RUVBL1 RPF2 RPF2 MRTO4 MRTO4 YTHDC1 YTHDC1 DHX9 DHX9 Y1Q_0004251 Y1Q_0004251 NUFIP1 NUFIP1 SETX SETX GEMIN5 GEMIN5 RPL24 RPL24 NOP2 NOP2 CELF1 CELF1 EIF2D EIF2D PRPF3 PRPF3 RPS27L RPS27L FAM103A1 FAM103A1 MRPS11 MRPS11 SPATA6L SPATA6L SLU7 SLU7 CELF3 CELF3 RPL5 RPL5 PTBP2 PTBP2 PRPF31 PRPF31 RPS19 RPS19 XRCC5 XRCC5 LUC7L2 LUC7L2 RRP7A RRP7A EIF4B EIF4B ASCC3 ASCC3 EIF3I EIF3I RRS1 RRS1 PRKDC PRKDC Y1Q_0006972 Y1Q_0006972 Y1Q_0013270 Y1Q_0013270 ADAR ADAR SRPK3-2 SRPK3-2 DDX28 DDX28 NUDT21 NUDT21 EIF3F EIF3F Y1Q_0008457 Y1Q_0008457 Y1Q_0006899 Y1Q_0006899 ZNHIT2 ZNHIT2 EIF3J EIF3J DDX20 DDX20 MDN1 MDN1 MDN1-2 MDN1-2 RPL23A RPL23A SNRPB SNRPB PUF60 PUF60 Y1Q_0009685 Y1Q_0009685 CELF4 CELF4 BRIX1 BRIX1 DHX29 DHX29
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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EIF3MEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (374 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (344 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (445 aa)
TRAF7E3 ubiquitin-protein ligase TRAF7. (670 aa)
GLTSCR2Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (409 aa)
ISY1Pre-mRNA-splicing factor ISY1-like protein. (281 aa)
PRPF6Pre-mRNA-processing factor 6. (941 aa)
ZRSR2U2 small nuclear ribonucleoprotein auxiliary factor subunit-related protein 2. (472 aa)
EIF2S3Eukaryotic translation initiation factor 2 subunit 3. (472 aa)
GEMIN8Gem-associated protein 8. (235 aa)
Y1Q_0016140Survival of motor neuron protein-like. (251 aa)
Y1Q_0008192Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family. (126 aa)
EIF3BEukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (688 aa)
PRMT5Protein arginine N-methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (242 aa)
LUC7L3-1Luc7-like protein 3 isoform C. (462 aa)
COILCoilin. (612 aa)
MRPS728S ribosomal protein S7, mitochondrial. (233 aa)
Y1Q_0009070Olfactory receptor. (317 aa)
MRPL2039S ribosomal protein L20, mitochondrial. (159 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3. (126 aa)
RPLP060S acidic ribosomal protein P0. (367 aa)
SF3A1Splicing factor 3A subunit 1. (787 aa)
CLNS1AMethylosome subunit pICln. (232 aa)
EIF4HEukaryotic translation initiation factor 4H. (256 aa)
ZNHIT3Zinc finger HIT domain-containing protein 3; Belongs to the G-protein coupled receptor 1 family. (230 aa)
Y1Q_0000382UPF0469 KIAA0907-like protein. (709 aa)
BOP1Ribosome biogenesis protein BOP1. (188 aa)
ERAL1GTPase Era, mitochondrial. (452 aa)
SRPK2SRSF protein kinase 2 isoform A. (691 aa)
DHX30Putative ATP-dependent RNA helicase DHX30 isoform A. (1184 aa)
FASTKD2FAST kinase domain-containing protein 2. (445 aa)
SF3B1Splicing factor 3B subunit 1. (1301 aa)
GEMIN4Gem-associated protein 4. (1061 aa)
NLE1Notchless protein-like protein 1 isoform A. (481 aa)
SNRPESmall nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
CRNKL1Crooked neck-like protein 1. (693 aa)
SRPK3-1SRSF protein kinase 3. (221 aa)
PIH1D2PIH1 domain-containing protein 2. (240 aa)
SF3A3Splicing factor 3A subunit 3. (501 aa)
SHDSH2 domain-containing adapter protein D. (237 aa)
SF3A2Splicing factor 3A subunit 2. (307 aa)
LUC7L-1Putative RNA-binding protein Luc7-like 1 isoform C. (360 aa)
EIF3LEukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (564 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (111 aa)
CUNH12orf45Uncharacterized protein. (112 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (593 aa)
STRAPSerine-threonine kinase receptor-associated protein. (350 aa)
ZNHIT6Box C/D snoRNA protein 1. (313 aa)
PIH1D1PIH1 domain-containing protein 1. (310 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (461 aa)
GEMIN2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (274 aa)
CDC73Parafibromin. (531 aa)
MCTS1Malignant T-cell-amplified sequence. (181 aa)
PRPF8Pre-mRNA-processing-splicing factor 8. (2260 aa)
Y1Q_0006637PRMT5_TIM domain-containing protein. (211 aa)
PRPF18Pre-mRNA-splicing factor 18. (342 aa)
Y1Q_0023357Protein kinase domain-containing protein. (822 aa)
ABT1Activator of basal transcription 1 isoform B. (282 aa)
CELF2CUGBP Elav-like family member 2 isoform D. (528 aa)
Y1Q_0005435Pre-mRNA-splicing factor SYF1-like. (113 aa)
PWP2Periodic tryptophan 2-like protein. (910 aa)
SFSWAPSplicing factor, suppressor of white-apricot-like protein isoform A. (949 aa)
SART3Squamous cell carcinoma antigen recognized by T-cells 3. (962 aa)
DENRDensity-regulated protein; Belongs to the DENR family. (198 aa)
RPL660S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (257 aa)
USP39U4/U6.U5 tri-snRNP-associated protein 2. (526 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
EIF3AEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1281 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa)
RPL3860S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
CCDC94Coiled-coil domain-containing protein 94. (330 aa)
EIF3CEukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (909 aa)
CPSF7Cleavage and polyadenylation specificity factor subunit 7. (493 aa)
PRPF19Pre-mRNA-processing factor 19. (492 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa)
CELF5Uncharacterized protein. (506 aa)
PSIP1PC4 and SFRS1-interacting protein isoform B. (602 aa)
RPSA40S ribosomal protein SA. (149 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (115 aa)
SNRPGSmall nuclear ribonucleoprotein G. (76 aa)
EIF3KEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (201 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (857 aa)
EIF5Eukaryotic translation initiation factor 5. (458 aa)
DICER1Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily. (1919 aa)
NAF1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (335 aa)
PTGES3Prostaglandin E synthase 3. (164 aa)
PRPF39Pre-mRNA-processing factor 39-like. (748 aa)
Y1Q_0013170Uncharacterized protein. (100 aa)
SCAF11Protein SCAF11. (1046 aa)
CPSF6Cleavage and polyadenylation specificity factor subunit 6 isoform A. (479 aa)
EIF3GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (333 aa)
RPS1540S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (161 aa)
XAB2Pre-mRNA-splicing factor SYF1. (747 aa)
AGO1Uncharacterized protein; Belongs to the argonaute family. (857 aa)
EIF2C4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (878 aa)
EIF2C3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (860 aa)
SMNSurvival motor neuron protein. (282 aa)
SNRPFSmall nuclear ribonucleoprotein F. (86 aa)
RPS2740S ribosomal protein S27. (84 aa)
CCDC105Coiled-coil domain-containing protein 105. (509 aa)
RPS540S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (514 aa)
PRMT7Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (698 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (170 aa)
BOP1LRibosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (649 aa)
CELF6CUGBP Elav-like family member 6 isoform D. (485 aa)
SHQ1SHQ1-like protein. (511 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2. (310 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
RPF2Ribosome production factor 2-like protein. (307 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (238 aa)
YTHDC1YTH domain-containing protein 1 isoform A. (715 aa)
DHX9ATP-dependent RNA helicase A. (1546 aa)
Y1Q_0004251RL10P_insert domain-containing protein. (178 aa)
NUFIP1Nuclear fragile X mental retardation-interacting protein 1. (525 aa)
SETXPutative helicase senataxin. (1732 aa)
GEMIN5Gem-associated protein 5 isoform A. (1507 aa)
RPL2460S ribosomal protein L24. (157 aa)
NOP2Putative 28S rRNA (Cytosine(4447)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (776 aa)
CELF1Uncharacterized protein. (495 aa)
EIF2DEukaryotic translation initiation factor 2D. (602 aa)
PRPF3U4/U6 small nuclear ribonucleoprotein Prp3. (682 aa)
RPS27L40S ribosomal protein S27. (84 aa)
FAM103A1RNMT-activating mini protein. (149 aa)
MRPS1128S ribosomal protein S11, mitochondrial; Belongs to the universal ribosomal protein uS11 family. (190 aa)
SPATA6LSpermatogenesis associated 6-like protein. (417 aa)
SLU7Pre-mRNA-splicing factor SLU7. (612 aa)
CELF3Uncharacterized protein. (455 aa)
RPL560S ribosomal protein L5. (317 aa)
PTBP2Uncharacterized protein. (537 aa)
PRPF31U4/U6 small nuclear ribonucleoprotein Prp31 isoform B. (515 aa)
RPS1940S ribosomal protein S19. (515 aa)
XRCC5X-ray repair cross-complementing protein 5 isoform A. (857 aa)
LUC7L2LUC7-like 2. (378 aa)
RRP7ARibosomal RNA-processing 7-like protein A. (277 aa)
EIF4BEukaryotic translation initiation factor 4B. (630 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2136 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (325 aa)
RRS1Ribosome biogenesis regulatory protein-like protein. (198 aa)
PRKDCDNA-dependent protein kinase catalytic subunit isoform B; Belongs to the PI3/PI4-kinase family. (4144 aa)
Y1Q_0006972Uncharacterized protein. (555 aa)
Y1Q_0013270SRSF protein kinase 3-like; Belongs to the protein kinase superfamily. (358 aa)
ADARDouble-stranded RNA-specific adenosine deaminase. (1059 aa)
SRPK3-2SRSF protein kinase 3; Belongs to the protein kinase superfamily. (405 aa)
DDX28Putative ATP-dependent RNA helicase DDX28. (301 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (340 aa)
Y1Q_0008457Nucleolar protein 3-like. (196 aa)
Y1Q_0006899Suf domain-containing protein. (614 aa)
ZNHIT2Zinc finger HIT domain-containing protein 2. (497 aa)
EIF3JEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (254 aa)
DDX20Putative ATP-dependent RNA helicase DDX20; Belongs to the DEAD box helicase family. (475 aa)
MDN1Midasin. (487 aa)
MDN1-2Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5010 aa)
RPL23A60S ribosomal protein L23a. (144 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
PUF60Poly(U)-binding-splicing factor PUF60. (531 aa)
Y1Q_0009685Uncharacterized protein. (373 aa)
CELF4RRM domain-containing protein. (138 aa)
BRIX1Ribosome biogenesis BRX1-like protein. (343 aa)
DHX29ATP-dependent RNA helicase DHX29 isoform B. (1203 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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