95 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MMP14	ZnMc domain-containing protein. (570 aa)
	ELK1	ETS domain-containing protein Elk-1. (396 aa)
	ZFPM2	Zinc finger protein ZFPM2 isoform A. (1158 aa)
	CCBE1	Collagen and calcium-binding EGF domain-containing protein 1. (264 aa)
	Y1Q_0009788	Uncharacterized protein. (117 aa)
	CTSH	Pro-cathepsin H; Belongs to the peptidase C1 family. (334 aa)
	WNT2B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
	DAG1	Dystroglycan. (683 aa)
	DLG5	Disks large-like protein 5; Belongs to the MAGUK family. (1973 aa)
	ESRP2-2	RRM domain-containing protein. (732 aa)
	GLI1	Zinc finger protein GLI1. (476 aa)
	NKIRAS1	NF-kappa-B inhibitor-interacting Ras-like protein 1. (192 aa)
	HOXA5	Homeobox protein Hox-A5. (231 aa)
	TGFBR2-2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (546 aa)
	THRB	Uncharacterized protein. (423 aa)
	PHF14	PHD finger protein 14 isoform B. (882 aa)
	HOPX	Homeodomain-only protein. (105 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (340 aa)
	DNAAF1-1	Dynein assembly factor 1, axonemal. (755 aa)
	HSD11B1	Corticosteroid 11-beta-dehydrogenase isozyme 1. (317 aa)
	SEC24B	Uncharacterized protein. (1208 aa)
	ADAMTSL2	ADAMTS-like protein 2 isoform A. (886 aa)
	Y1Q_0018245	Timeless-like protein. (364 aa)
	PPP3R1	Calcineurin subunit B type 1. (170 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A. (1011 aa)
	RC3H2-2	Uncharacterized protein. (1160 aa)
	ADAMTSL2-2	PLAC domain-containing protein. (989 aa)
	PTK7	Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1081 aa)
	STRA6	Stimulated by retinoic acid 6 protein-like protein. (720 aa)
	FGF7-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)
	ATXN1L	Ataxin-1-like. (603 aa)
	PDPN-1	Podoplanin isoform A. (148 aa)
	FLT1	Vascular endothelial growth factor receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1725 aa)
	FGF1-1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	Y1Q_0010680	Uncharacterized protein. (176 aa)
	HSPB11	Intraflagellar transport 25-like protein. (141 aa)
	CTGF	Connective tissue growth factor. (341 aa)
	TCF21	Transcription factor 21. (179 aa)
	IGFBP5	Insulin-like growth factor-binding protein 5. (184 aa)
	IGFBP5-2	IGFBP N-terminal domain-containing protein. (144 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (789 aa)
	SP3	Transcription factor Sp3. (766 aa)
	ERRFI1	ERBB receptor feedback inhibitor 1. (453 aa)
	NUMA1	Nuclear mitotic apparatus protein 1. (2422 aa)
	GATA6	Transcription factor GATA-6. (325 aa)
	EDN2	Endothelin-2. (181 aa)
	STK40	Serine/threonine-protein kinase 40. (571 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (382 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	THRA	Thyroid hormone receptor alpha. (408 aa)
	NKIRAS2	NF-kappa-B inhibitor-interacting Ras-like protein 2. (191 aa)
	TTC25	2',3'-cyclic-nucleotide 3'-phosphodiesterase. (1005 aa)
	FBXW7-2	Uncharacterized protein. (674 aa)
	RXFP1-2	G_PROTEIN_RECEP_F1_2 domain-containing protein. (619 aa)
	KDR	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1353 aa)
	PKDCCB	Extracellular tyrosine-protein kinase PKDCC. (311 aa)
	MYOCD	Myocardin isoform A. (934 aa)
	Y1Q_0019415	Uncharacterized protein. (85 aa)
	ITGA3-2	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1085 aa)
	HPS1	Hermansky-Pudlak syndrome 1 protein. (716 aa)
	PKDCC	Extracellular tyrosine-protein kinase PKDCC. (378 aa)
	CTNNB1	Catenin beta-1 isoform B. (783 aa)
	GLI3	Uncharacterized protein. (1572 aa)
	TGFB1	TGF_BETA_2 domain-containing protein. (242 aa)
	CTSZ	Cathepsin Z; Belongs to the peptidase C1 family. (303 aa)
	EPAS1	Endothelial PAS domain-containing protein 1. (863 aa)
	BAG6	Large proline-rich protein BAG6. (945 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (179 aa)
	NPM3	Nucleoplasmin-3; Belongs to the heparin-binding growth factors family. (345 aa)
	DSPP	Dentin sialophosphoprotein isoform A. (931 aa)
	HHIP	Hedgehog-interacting protein isoform A. (683 aa)
	CCDC40	Coiled-coil domain-containing protein 40. (1131 aa)
	NKX2-8	Homeobox protein Nkx-2.8. (218 aa)
	TAB1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (502 aa)
	Y1Q_0024227	Uncharacterized protein. (490 aa)
	Y1Q_0024039	KIX domain-containing protein. (131 aa)
	CREBBP	CREB-binding protein isoform C. (2208 aa)
	SLC7A11	Cystine/glutamate transporter. (503 aa)
	TMEM38B	Trimeric intracellular cation channel type B. (288 aa)
	TIMELESS	Timeless-like protein. (616 aa)
	RBBP9	Putative hydrolase RBBP9. (190 aa)
	Y1Q_0017188	Uncharacterized protein. (164 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1. (327 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	FBXW7	F-box/WD repeat-containing protein 7. (665 aa)
	FBXW9	F-box/WD repeat-containing protein 9. (457 aa)
	LIF	Leukemia inhibitory factor. (211 aa)
	Y1Q_0022796	Uncharacterized protein. (109 aa)
	Y1Q_0022798	Hydroxysteroid 11-beta-dehydrogenase 1-like protein A. (105 aa)
	SAV1	Salvador-like protein 1. (391 aa)
	JMJD6	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6. (414 aa)
	Y1Q_0016466	Uncharacterized protein. (4317 aa)
	PKD1	Polycystin-1. (4307 aa)
	AIMP2-1	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform A. (316 aa)
	PHEX	Phosphate-regulating neutral endopeptidase. (751 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG6	Y1Q_0017188	A0A151NWF2	A0A151NCQ2	Large proline-rich protein BAG6.	Uncharacterized protein.	0.942
BMPR2	TGFB1	A0A151N9A5	A0A151P039	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TGF_BETA_2 domain-containing protein.	0.469
CCBE1	Y1Q_0009788	A0A151MWS2	A0A151MWP1	Collagen and calcium-binding EGF domain-containing protein 1.	Uncharacterized protein.	0.931
CCDC40	DNAAF1-1	A0A151NKJ4	A0A151MLK1	Coiled-coil domain-containing protein 40.	Dynein assembly factor 1, axonemal.	0.669
CREB1	CREBBP	A0A151N9K7	A0A151NHH3	Cyclic AMP-responsive element-binding protein 1.	CREB-binding protein isoform C.	0.973
CREB1	CTNNB1	A0A151N9K7	A0A151P2N9	Cyclic AMP-responsive element-binding protein 1.	Catenin beta-1 isoform B.	0.658
CREB1	Y1Q_0024039	A0A151N9K7	A0A151NHX4	Cyclic AMP-responsive element-binding protein 1.	KIX domain-containing protein.	0.873
CREBBP	CREB1	A0A151NHH3	A0A151N9K7	CREB-binding protein isoform C.	Cyclic AMP-responsive element-binding protein 1.	0.973
CREBBP	CTNNB1	A0A151NHH3	A0A151P2N9	CREB-binding protein isoform C.	Catenin beta-1 isoform B.	0.904
CREBBP	EPAS1	A0A151NHH3	A0A151NWI5	CREB-binding protein isoform C.	Endothelial PAS domain-containing protein 1.	0.826
CREBBP	GATA6	A0A151NHH3	A0A151PGM5	CREB-binding protein isoform C.	Transcription factor GATA-6.	0.489
CREBBP	TGFB1	A0A151NHH3	A0A151P039	CREB-binding protein isoform C.	TGF_BETA_2 domain-containing protein.	0.467
CTGF	TGFB1	A0A151M3F2	A0A151P039	Connective tissue growth factor.	TGF_BETA_2 domain-containing protein.	0.631
CTGF	TGFBR2-2	A0A151M3F2	A0A151MQZ6	Connective tissue growth factor.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.458
CTNNB1	CREB1	A0A151P2N9	A0A151N9K7	Catenin beta-1 isoform B.	Cyclic AMP-responsive element-binding protein 1.	0.658
CTNNB1	CREBBP	A0A151P2N9	A0A151NHH3	Catenin beta-1 isoform B.	CREB-binding protein isoform C.	0.904
CTNNB1	EPAS1	A0A151P2N9	A0A151NWI5	Catenin beta-1 isoform B.	Endothelial PAS domain-containing protein 1.	0.496
CTNNB1	GLI1	A0A151P2N9	A0A151MRB2	Catenin beta-1 isoform B.	Zinc finger protein GLI1.	0.491
CTNNB1	NPM3	A0A151P2N9	A0A151NP53	Catenin beta-1 isoform B.	Nucleoplasmin-3; Belongs to the heparin-binding growth factors family.	0.408
CTNNB1	TGFB1	A0A151P2N9	A0A151P039	Catenin beta-1 isoform B.	TGF_BETA_2 domain-containing protein.	0.538