(44 nodes) Secretory granule membrane network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCAMP1	Secretory carrier-associated membrane protein. (328 aa)
	CCDC136	Coiled-coil domain-containing protein 136-like. (453 aa)
	SCG3	Secretogranin-3 isoform A. (494 aa)
	SYT9-2	Uncharacterized protein. (524 aa)
	ACRBP	Acrosin-binding protein. (317 aa)
	PLA1A	Phospholipase A1 member A. (533 aa)
	HYAL3-1	Hyaluronidase. (644 aa)
	DBH	Dopamine beta-hydroxylase. (598 aa)
	TMEM190L	Transmembrane protein 190 isoform A. (159 aa)
	IZUMO1	Izumo sperm-egg fusion protein 1. (152 aa)
	CFAP65	Coiled-coil domain-containing protein 108 isoform B. (1732 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (1680 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	Y1Q_0023796	Uncharacterized protein. (1088 aa)
	TMED10	Transmembrane emp24 domain-containing protein 10. (209 aa)
	STBD1	Starch-binding domain-containing protein 1. (359 aa)
	ITPR2-2	Uncharacterized protein. (2702 aa)
	PAM	Peptidyl-glycine alpha-amidating monooxygenase isoform B. (871 aa)
	SPACA1	Sperm acrosome membrane-associated protein 1. (307 aa)
	SYT4	Synaptotagmin-4. (425 aa)
	VPS13B	Vacuolar protein sorting-associated protein 13B-like. (3653 aa)
	TMEM184A	Uncharacterized protein. (412 aa)
	RAB26	Ras-related protein Rab-26. (244 aa)
	FAM170B	Uncharacterized protein. (299 aa)
	SYT2	Synaptotagmin-2. (398 aa)
	Y1Q_0024284	Uncharacterized protein. (314 aa)
	SYT5-2	Uncharacterized protein. (451 aa)
	MOXD1-1	DBH-like monooxygenase protein 1 isoform A. (766 aa)
	PHACTR2	Phosphatase and actin regulator. (567 aa)
	LAMP2-1	Lysosome-associated membrane glycoprotein 2 isoform C. (470 aa)
	SYTL4	Synaptotagmin-like protein 4. (691 aa)
	TMED2	Transmembrane emp24 domain-containing protein 2 isoform B. (201 aa)
	VAMP8	Vesicle-associated membrane protein 8. (94 aa)
	TEKT3	Tektin-3 isoform B. (536 aa)
	SLC17A9	Solute carrier family 17 member 9. (429 aa)
	ZPBP-1	Zona pellucida-binding protein 1 isoform C. (407 aa)
	SYCN	Syncollin. (123 aa)
	ITPR3	Uncharacterized protein. (2667 aa)
	TRIP11	Thyroid receptor-interacting protein 11. (347 aa)
	VGF	Neurosecretory protein VGF isoform B. (503 aa)
	CYB561	Cytochrome b561. (253 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (158 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	SYT5	Synaptotagmin-5 isoform B. (426 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	CAV2	A0A151PF23	A0A151PEZ6	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.992
CAV1	CAV3	A0A151PF23	A0A151MKB4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV2	CAV1	A0A151PEZ6	A0A151PF23	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.992
CAV2	CAV3	A0A151PEZ6	A0A151MKB4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.992
CAV3	CAV1	A0A151MKB4	A0A151PF23	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV3	CAV2	A0A151MKB4	A0A151PEZ6	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.992
CYB561	DBH	A0A151PBX1	A0A151MFR9	Cytochrome b561.	Dopamine beta-hydroxylase.	0.499
CYB561	PAM	A0A151PBX1	A0A151PIV2	Cytochrome b561.	Peptidyl-glycine alpha-amidating monooxygenase isoform B.	0.542
DBH	CYB561	A0A151MFR9	A0A151PBX1	Dopamine beta-hydroxylase.	Cytochrome b561.	0.499
ITPR2	ITPR2-2	A0A151MK79	A0A151MPL6	Inositol 1,4,5-trisphosphate receptor type 2.	Uncharacterized protein.	0.901
ITPR2	ITPR3	A0A151MK79	A0A151P4X0	Inositol 1,4,5-trisphosphate receptor type 2.	Uncharacterized protein.	0.903
ITPR2	Y1Q_0023796	A0A151MK79	A0A151MKE7	Inositol 1,4,5-trisphosphate receptor type 2.	Uncharacterized protein.	0.949
ITPR2-2	ITPR2	A0A151MPL6	A0A151MK79	Uncharacterized protein.	Inositol 1,4,5-trisphosphate receptor type 2.	0.901
ITPR2-2	ITPR3	A0A151MPL6	A0A151P4X0	Uncharacterized protein.	Uncharacterized protein.	0.902
ITPR3	ITPR2	A0A151P4X0	A0A151MK79	Uncharacterized protein.	Inositol 1,4,5-trisphosphate receptor type 2.	0.903
ITPR3	ITPR2-2	A0A151P4X0	A0A151MPL6	Uncharacterized protein.	Uncharacterized protein.	0.902
IZUMO1	SPACA1	A0A151MGL1	A0A151MTX1	Izumo sperm-egg fusion protein 1.	Sperm acrosome membrane-associated protein 1.	0.616
IZUMO1	TMEM190L	A0A151MGL1	A0A151MG99	Izumo sperm-egg fusion protein 1.	Transmembrane protein 190 isoform A.	0.551
PAM	CYB561	A0A151PIV2	A0A151PBX1	Peptidyl-glycine alpha-amidating monooxygenase isoform B.	Cytochrome b561.	0.542
SPACA1	IZUMO1	A0A151MTX1	A0A151MGL1	Sperm acrosome membrane-associated protein 1.	Izumo sperm-egg fusion protein 1.	0.616