63 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RUVBL2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (461 aa)
	XBP1	X-box-binding protein 1. (286 aa)
	ATRX	Transcriptional regulator ATRX. (2331 aa)
	LEMD2	LEM domain-containing protein 2. (282 aa)
	CEBPB	CCAAT/enhancer-binding protein beta. (141 aa)
	H2AFY2	Core histone macro-H2A.2; Belongs to the histone H2A family. (339 aa)
	SBNO2-2	Uncharacterized protein. (1428 aa)
	TOX4	TOX high mobility group box family member 4 isoform A. (491 aa)
	NUP50	Nuclear pore complex protein Nup50. (520 aa)
	KDM3A	JmjC domain-containing protein. (1327 aa)
	PPARGC1A	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform A. (555 aa)
	STAT4	Signal transducer and activator of transcription. (849 aa)
	THRA	Thyroid hormone receptor alpha. (408 aa)
	LEMD3	Inner nuclear membrane protein Man1 isoform B. (622 aa)
	HMGA2	High mobility group protein HMGI-C. (112 aa)
	KDM6B	Lysine-specific demethylase 6B isoform A. (1401 aa)
	SBNO2	Strawberry notch-like protein 2 isoform B. (1426 aa)
	OGT	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase subunit isoform B. (1075 aa)
	SIRT6	NAD-dependent protein deacetylase sirtuin-6. (357 aa)
	Y1Q_0007599	Uncharacterized protein. (420 aa)
	HIST1H110	Histone H1.10. (124 aa)
	Y1Q_0020094	Histone H1.01-like. (168 aa)
	HIST1H1T	Histone H1t. (203 aa)
	TBR1	T-box brain protein 1. (532 aa)
	APEX1	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
	H2AFY	Core histone macro-H2A.1 isoform C; Belongs to the histone H2A family. (435 aa)
	ZNF276	Zinc finger protein 276. (482 aa)
	NR1H3	Oxysterols receptor LXR-alpha. (408 aa)
	PAX6	Paired box protein Pax-6. (516 aa)
	MYOD1	Myogenic factor. (293 aa)
	HMGN1	Non-histone chromosomal protein HMG-14. (102 aa)
	POLE3	DNA polymerase epsilon subunit 3. (143 aa)
	KDM3B	Lysine-specific demethylase 3B isoform A. (1704 aa)
	DHX9	ATP-dependent RNA helicase A. (1546 aa)
	H1FX	Histone H1x. (220 aa)
	PRDM14	PR domain zinc finger protein 14. (193 aa)
	TOX	Thymocyte selection-associated high mobility group box protein TOX. (526 aa)
	VAX2	Ventral anterior homeobox 2. (306 aa)
	THRB	Uncharacterized protein. (423 aa)
	EOMES	Eomesodermin-like protein isoform B. (404 aa)
	TOX3-1	TOX high mobility group box family member 3 isoform A. (476 aa)
	HMGN3-1	High mobility group nucleosome-binding domain-containing protein 3 isoform A. (123 aa)
	JMJD1C	Uncharacterized protein. (155 aa)
	Y1Q_0006910	JmjC domain-containing protein. (1769 aa)
	GATA1	Erythroid transcription factor. (485 aa)
	GRHL2	CP2 domain-containing protein. (622 aa)
	Y1Q_0018485	Paired box protein Pax-6-like. (281 aa)
	SUZ12	Polycomb protein SUZ12. (667 aa)
	WBP2-1	WW domain-binding protein 2 isoform B. (263 aa)
	KDM6B-2	Uncharacterized protein. (1393 aa)
	GRHL1	Grainyhead-like 1-like protein isoform A. (630 aa)
	MYOG	Myogenin. (227 aa)
	Y1Q_0008724	Uncharacterized protein. (128 aa)
	HR-1	Lysine-specific demethylase hairless isoform A. (1685 aa)
	TOX2	TOX high mobility group box family member 2. (500 aa)
	RCC1	Regulator of chromosome condensation. (421 aa)
	WBP2NL	Postacrosomal sheath WW domain-binding protein. (278 aa)
	CREBBPA	CREB-binding protein isoform A. (1756 aa)
	CREBBP	CREB-binding protein isoform C. (2208 aa)
	H1F0	Histone H5. (187 aa)
	Y1Q_0024039	KIX domain-containing protein. (131 aa)
	KDM5A	Uncharacterized protein. (1692 aa)
	HMGN2	Non-histone chromosomal protein HMG-17. (72 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APEX1	CREBBP	A0A151M3T2	A0A151NHH3	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	CREB-binding protein isoform C.	0.557
APEX1	POLE3	A0A151M3T2	A0A151MEU2	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA polymerase epsilon subunit 3.	0.611
APEX1	Y1Q_0008724	A0A151M3T2	A0A151N9W6	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Uncharacterized protein.	0.611
APEX1	Y1Q_0024039	A0A151M3T2	A0A151NHX4	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	KIX domain-containing protein.	0.557
ATRX	CREBBPA	A0A151NNF0	A0A151NHE3	Transcriptional regulator ATRX.	CREB-binding protein isoform A.	0.415
ATRX	H2AFY	A0A151NNF0	A0A151M720	Transcriptional regulator ATRX.	Core histone macro-H2A.1 isoform C; Belongs to the histone H2A family.	0.477
ATRX	H2AFY2	A0A151NNF0	A0A151P0C2	Transcriptional regulator ATRX.	Core histone macro-H2A.2; Belongs to the histone H2A family.	0.408
ATRX	KDM6B	A0A151NNF0	A0A151NQS5	Transcriptional regulator ATRX.	Lysine-specific demethylase 6B isoform A.	0.450
CEBPB	CREBBP	A0A151NYY9	A0A151NHH3	CCAAT/enhancer-binding protein beta.	CREB-binding protein isoform C.	0.808
CEBPB	CREBBPA	A0A151NYY9	A0A151NHE3	CCAAT/enhancer-binding protein beta.	CREB-binding protein isoform A.	0.686
CEBPB	GATA1	A0A151NYY9	A0A151MUS2	CCAAT/enhancer-binding protein beta.	Erythroid transcription factor.	0.449
CEBPB	NR1H3	A0A151NYY9	A0A151MB42	CCAAT/enhancer-binding protein beta.	Oxysterols receptor LXR-alpha.	0.474
CEBPB	PPARGC1A	A0A151NYY9	A0A151P9W3	CCAAT/enhancer-binding protein beta.	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform A.	0.593
CEBPB	STAT4	A0A151NYY9	A0A151PC08	CCAAT/enhancer-binding protein beta.	Signal transducer and activator of transcription.	0.767
CEBPB	Y1Q_0024039	A0A151NYY9	A0A151NHX4	CCAAT/enhancer-binding protein beta.	KIX domain-containing protein.	0.688
CREBBP	APEX1	A0A151NHH3	A0A151M3T2	CREB-binding protein isoform C.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.557
CREBBP	CEBPB	A0A151NHH3	A0A151NYY9	CREB-binding protein isoform C.	CCAAT/enhancer-binding protein beta.	0.808
CREBBP	CREBBPA	A0A151NHH3	A0A151NHE3	CREB-binding protein isoform C.	CREB-binding protein isoform A.	0.952
CREBBP	GATA1	A0A151NHH3	A0A151MUS2	CREB-binding protein isoform C.	Erythroid transcription factor.	0.699
CREBBP	MYOD1	A0A151NHH3	A0A151MC43	CREB-binding protein isoform C.	Myogenic factor.	0.716