STRINGSTRING
ENSA ENSA IKBKB-2 IKBKB-2 PTPRC PTPRC GBA GBA ROCK2 ROCK2 VRK3-1 VRK3-1 CDH5 CDH5 AGTR2 AGTR2 STYXL1 STYXL1 SPPL3 SPPL3 GNA12 GNA12 TMEM130 TMEM130 ITGA1 ITGA1 PPP1R14D-1 PPP1R14D-1 CNEP1R1 CNEP1R1 MFHAS1 MFHAS1 SYMPKL SYMPKL SYMPK SYMPK PPP1R7 PPP1R7 PINK1 PINK1 TSC1 TSC1 PPP2R4 PPP2R4 NSMF NSMF TIPRL TIPRL AMBRA1 AMBRA1 CRY2-2 CRY2-2 ARPP19 ARPP19 PDGFRA PDGFRA BOD1 BOD1 PPP1R11 PPP1R11 MGAT5 MGAT5 ROCK1 ROCK1 PPP1R16A PPP1R16A Y1Q_0020688 Y1Q_0020688 NUAK1 NUAK1 Y1Q_0024190 Y1Q_0024190 PPP1R15A PPP1R15A PPP6R1 PPP6R1 Y1Q_0023392 Y1Q_0023392 MAGI2 MAGI2 Y1Q_0023488 Y1Q_0023488 TNF TNF CSNK2B CSNK2B ANKLE2 ANKLE2 LRRC43-1 LRRC43-1 PPP6R3-2 PPP6R3-2 DEF6 DEF6 PPP1R16B PPP1R16B YWHAB YWHAB TGFB1 TGFB1 PPP6R3 PPP6R3 PPP1R1B-1 PPP1R1B-1 CDCA2-1 CDCA2-1 LRRC46 LRRC46 SMPD1 SMPD1 LRRC30 LRRC30 PPP4R4 PPP4R4 BOD1L1 BOD1L1 HTT HTT MASTL MASTL PPP1R8 PPP1R8 CMYA5 CMYA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSAAlpha-endosulfine; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (122 aa)
IKBKB-2Uncharacterized protein. (757 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform D. (1209 aa)
GBAGlucosylceramidase. (779 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1396 aa)
VRK3-1Inactive serine/threonine-protein kinase VRK3 isoform A. (407 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (733 aa)
AGTR2Type-2 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (369 aa)
STYXL1Serine/threonine/tyrosine-interacting-like protein 1. (305 aa)
SPPL3Signal peptide peptidase-like 3. (384 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12 isoform A. (383 aa)
TMEM130Transmembrane protein 130. (487 aa)
ITGA1VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1137 aa)
PPP1R14D-1Protein phosphatase 1 regulatory subunit 14D isoform B. (126 aa)
CNEP1R1Nuclear envelope phosphatase-regulatory subunit 1. (125 aa)
MFHAS1Malignant fibrous histiocytoma-amplified sequence 1. (868 aa)
SYMPKLSymplekin. (501 aa)
SYMPKSymplekin. (702 aa)
PPP1R7Protein phosphatase 1 regulatory subunit 7 isoform C. (388 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the arginase family. (851 aa)
TSC1Hamartin isoform B. (1115 aa)
PPP2R4Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (321 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor isoform A. (522 aa)
TIPRLTIP41-like protein. (275 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform A. (1224 aa)
CRY2-2Photolyase/cryptochrome alpha/beta domain-containing protein. (547 aa)
ARPP19cAMP-regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (112 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1097 aa)
BOD1Biorientation of chromosomes in cell division protein 1. (163 aa)
PPP1R11Protein phosphatase 1 regulatory subunit 11. (142 aa)
MGAT5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A. (716 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1377 aa)
PPP1R16AProtein phosphatase 1 regulatory subunit 16A. (537 aa)
Y1Q_0020688Glucosylceramidase. (347 aa)
NUAK1NUAK family SNF1-like kinase 1. (651 aa)
Y1Q_0024190HATPase_c domain-containing protein. (755 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (374 aa)
PPP6R1Uncharacterized protein. (1053 aa)
Y1Q_0023392PDZ domain-containing protein. (102 aa)
MAGI2Uncharacterized protein. (1393 aa)
Y1Q_0023488Centriolin-like. (467 aa)
TNFTumor necrosis factor. (231 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (249 aa)
ANKLE2Ankyrin repeat and LEM domain-containing protein 2. (820 aa)
LRRC43-1Leucine-rich repeat-containing protein 43 isoform B. (599 aa)
PPP6R3-2Uncharacterized protein. (873 aa)
DEF6Differentially expressed in FDCP 6-like protein. (607 aa)
PPP1R16BANK_REP_REGION domain-containing protein. (570 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (300 aa)
TGFB1TGF_BETA_2 domain-containing protein. (242 aa)
PPP6R3Serine/threonine-protein phosphatase 6 regulatory subunit 3. (907 aa)
PPP1R1B-1Protein phosphatase 1 regulatory subunit 1B isoform A. (243 aa)
CDCA2-1Cell division cycle-associated protein 2 isoform A. (814 aa)
LRRC46Leucine-rich repeat-containing protein 46. (333 aa)
SMPD1Sphingomyelin phosphodiesterase. (287 aa)
LRRC30Leucine-rich repeat-containing protein 30. (263 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform A. (864 aa)
BOD1L1Biorientation of chromosomes in cell division protein 1-like 1. (2023 aa)
HTTHuntingtin isoform A. (3112 aa)
MASTLSerine/threonine-protein kinase greatwall. (857 aa)
PPP1R8Nuclear inhibitor of protein phosphatase 1. (353 aa)
CMYA5Cardiomyopathy-associated protein 5. (2753 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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