STRINGSTRING
FBXL3 FBXL3 FBXL3-2 FBXL3-2 PPP1CC PPP1CC FBL12 FBL12 PER1 PER1 CRTC1 CRTC1 OPN5 OPN5 CRY2-2 CRY2-2 PML PML FBXL22 FBXL22 CRY1 CRY1 Y1Q_0021893 Y1Q_0021893 BHLHE40 BHLHE40 FBXL8 FBXL8 PPP1CA-2 PPP1CA-2 TP53 TP53 CRY2 CRY2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBXL3F-box/LRR-repeat protein 3. (397 aa)
FBXL3-2F-box domain-containing protein. (455 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
FBL12F-box/LRR-repeat protein 12. (319 aa)
PER1Period circadian protein-like protein 3. (1366 aa)
CRTC1CREB-regulated transcription coactivator 1 isoform A. (584 aa)
OPN5Opsin-5; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CRY2-2Photolyase/cryptochrome alpha/beta domain-containing protein. (547 aa)
PMLProtein PML isoform B. (586 aa)
FBXL22F-box and leucine-rich protein 22. (141 aa)
CRY1Cryptochrome 4. (665 aa)
Y1Q_0021893PAS domain-containing protein. (1057 aa)
BHLHE40Class E basic helix-loop-helix protein 40 isoform B. (283 aa)
FBXL8F-box/LRR-repeat protein 8. (385 aa)
PPP1CA-2Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
CRY2Cryptochrome-2. (506 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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