STRINGSTRING
AAED1 AAED1 ZBTB20 ZBTB20 APP APP HTR2A HTR2A SCARB2 SCARB2 TP53 TP53 PRKAA1-2 PRKAA1-2 FLCN FLCN MLXIPL MLXIPL CREBBP CREBBP Y1Q_0024039 Y1Q_0024039 P2RX7 P2RX7 OGT OGT EIF6 EIF6 ZBTB7A ZBTB7A SIRT6 SIRT6 DDIT4 DDIT4 TIGAR TIGAR PPARAB PPARAB STAT4 STAT4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AAED1Thioredoxin-like protein AAED1 isoform A. (244 aa)
ZBTB20Zinc finger and BTB domain-containing protein 20. (769 aa)
APPBPTI/Kunitz inhibitor domain-containing protein. (743 aa)
HTR2A5-hydroxytryptamine receptor 2A; Belongs to the G-protein coupled receptor 1 family. (489 aa)
SCARB2Lysosome membrane protein 2; Belongs to the CD36 family. (482 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
PRKAA1-2Non-specific serine/threonine protein kinase. (547 aa)
FLCNFolliculin. (629 aa)
MLXIPLCarbohydrate-responsive element-binding protein. (711 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (469 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase subunit isoform B. (1075 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa)
ZBTB7AZinc finger and BTB domain-containing protein 7A. (555 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (357 aa)
DDIT4DNA damage-inducible transcript 4 protein. (172 aa)
TIGARFructose-2,6-bisphosphatase TIGAR. (272 aa)
PPARABPeroxisome proliferator-activated receptor alpha. (438 aa)
STAT4Signal transducer and activator of transcription. (849 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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