STRINGSTRING
NR4A1 NR4A1 NR4A2 NR4A2 FAM120B FAM120B GLIS1 GLIS1 LRRC8C-2 LRRC8C-2 DIO2 DIO2 ADIPOQ ADIPOQ ADRB2 ADRB2 SMAD6 SMAD6 CNTN2-2 CNTN2-2 LRG1 LRG1 LRRN4CL LRRN4CL MKKS MKKS CTBP1 CTBP1 RNASEL RNASEL PTGS2 PTGS2 LAMB3 LAMB3 LAMA4 LAMA4 Y1Q_0005880 Y1Q_0005880 CLIP3-2 CLIP3-2 PSMB8 PSMB8 Y1Q_0005879 Y1Q_0005879 CEBPD CEBPD BBS1-1 BBS1-1 STEAP4 STEAP4 BBS2 BBS2 NIPBL NIPBL WNT1 WNT1 SOCS1 SOCS1 SOX8 SOX8 DHRS7B-1 DHRS7B-1 PRDM16 PRDM16 SDF4 SDF4 TMEM120A TMEM120A PRLHL PRLHL ADRB3 ADRB3 BSCL2 BSCL2 ZNF516 ZNF516 CREBBP CREBBP Y1Q_0024039 Y1Q_0024039 ALDH6A1 ALDH6A1 FAM134B FAM134B TMEM120B TMEM120B FFAR2 FFAR2 ADRB1 ADRB1 METRNL METRNL ZBTB7A ZBTB7A CEBPB CEBPB NOC3L NOC3L SIRT1 SIRT1 PLACL2 PLACL2 FFAR4 FFAR4 Y1Q_0017512 Y1Q_0017512 Y1Q_0017513 Y1Q_0017513 BBS9 BBS9 CTBP2 CTBP2 MED1 MED1 MED1-2 MED1-2 TTC8 TTC8 CTBP1-2 CTBP1-2 FBXO9 FBXO9 BBS7 BBS7 ANKRD26 ANKRD26 OSBPL5 OSBPL5 HMGA2 HMGA2 NR4A3 NR4A3 ATF5 ATF5 ADGRF5 ADGRF5 PPARG PPARG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NR4A1Nuclear receptor subfamily 4 group A member 1. (579 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2 isoform B. (405 aa)
FAM120BConstitutive coactivator of peroxisome proliferator-activated receptor gamma isoform A. (671 aa)
GLIS1Zinc finger protein GLIS1 isoform B. (784 aa)
LRRC8C-2Pannexin_like domain-containing protein. (816 aa)
DIO2Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (78 aa)
ADIPOQAdiponectin. (263 aa)
ADRB2Beta-2 adrenergic receptor. (392 aa)
SMAD6Mothers against decapentaplegic homolog. (265 aa)
CNTN2-2Uncharacterized protein. (1032 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (406 aa)
LRRN4CLLRRN4 C-terminal-like protein. (261 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (237 aa)
CTBP1C-terminal-binding protein 1 isoform B. (501 aa)
RNASEL2-5A-dependent ribonuclease. (732 aa)
PTGS2Prostaglandin G/H synthase 2. (605 aa)
LAMB3Laminin subunit beta-3 isoform B. (1232 aa)
LAMA4Laminin subunit alpha-4. (1825 aa)
Y1Q_0005880Free fatty acid receptor 2-like; Belongs to the G-protein coupled receptor 1 family. (355 aa)
CLIP3-2Uncharacterized protein. (531 aa)
PSMB8Proteasome subunit beta. (282 aa)
Y1Q_0005879G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (322 aa)
CEBPDCCAAT/enhancer-binding protein delta. (124 aa)
BBS1-1Bardet-Biedl syndrome 1 protein isoform A. (590 aa)
STEAP4Metalloreductase STEAP4 isoform A. (429 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (731 aa)
NIPBLNipped-B protein. (2617 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
SOCS1Suppressor of cytokine signaling 1. (207 aa)
SOX8Transcription factor SOX-8. (471 aa)
DHRS7B-1Dehydrogenase/reductase SDR family member 7B isoform A; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (365 aa)
PRDM16Uncharacterized protein. (1167 aa)
SDF4Calcium-binding protein. (356 aa)
TMEM120ATransmembrane protein 120A. (349 aa)
PRLHLProlactin-releasing peptide. (138 aa)
ADRB3Beta-3 adrenergic receptor. (439 aa)
BSCL2Seipin. (353 aa)
ZNF516Zinc finger protein 516 isoform A. (1299 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
ALDH6A1Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. (540 aa)
FAM134BReticulophagy receptor FAM134B. (463 aa)
TMEM120BTransmembrane protein 120B. (333 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (322 aa)
ADRB1Beta-1 adrenergic receptor. (383 aa)
METRNLMeteorin-like protein. (292 aa)
ZBTB7AZinc finger and BTB domain-containing protein 7A. (555 aa)
CEBPBCCAAT/enhancer-binding protein beta. (141 aa)
NOC3LNucleolar complex protein 3 homolog. (800 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1. (634 aa)
PLACL2Placenta-specific 8 protein-like. (132 aa)
FFAR4Free fatty acid receptor 4. (353 aa)
Y1Q_0017512Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (345 aa)
Y1Q_0017513Mediator of RNA polymerase II transcription subunit 1-like. (204 aa)
BBS9Protein PTHB1 isoform B. (879 aa)
CTBP2Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (461 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1104 aa)
MED1-2Uncharacterized protein. (259 aa)
TTC8Tetratricopeptide repeat protein 8. (511 aa)
CTBP1-2Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (451 aa)
FBXO9F-box only protein 9 isoform A. (389 aa)
BBS7Bardet-Biedl syndrome 7 protein. (696 aa)
ANKRD26Ankyrin repeat domain-containing protein 26 isoform A. (824 aa)
OSBPL5Oxysterol-binding protein; Belongs to the OSBP family. (892 aa)
HMGA2High mobility group protein HMGI-C. (112 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (634 aa)
ATF5Cyclic AMP-dependent transcription factor ATF-5. (293 aa)
ADGRF5Adhesion G protein-coupled receptor F5 isoform A; Belongs to the G-protein coupled receptor 2 family. (1294 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (453 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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