(12 nodes) Positive regulation of bone resorption network (Alligator mississippiensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Others

textmining

co-expression

protein homology

Your Input:
	PLEKHM1	Pleckstrin-like proteiny domain-containing family M member 1. (1071 aa)
	SPP1	Osteopontin. (314 aa)
	TMEM64	Transmembrane protein 64 isoform A. (566 aa)
	PPARGC1B	Peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform A. (1037 aa)
	SYK-2	Tyrosine-protein kinase. (608 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (271 aa)
	DCSTAMP	Dendritic cell-specific transmembrane protein. (165 aa)
	TNFRSF11A	Tumor necrosis factor receptor superfamily member 11A. (669 aa)
	MC4R	Melanocortin receptor 4. (331 aa)
	Y1Q_0021150	DUF4206 domain-containing protein. (177 aa)
	DEF8	Differentially expressed in FDCP 8-like protein. (277 aa)
	ITGB3-2	Integrin beta; Belongs to the integrin beta chain family. (783 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCSTAMP	TNFRSF11A	A0A151MXT9	A0A151NFD7	Dendritic cell-specific transmembrane protein.	Tumor necrosis factor receptor superfamily member 11A.	0.490
DCSTAMP	TNFSF11	A0A151MXT9	A0A151MHR5	Dendritic cell-specific transmembrane protein.	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	0.625
DEF8	Y1Q_0021150	A0A151NJW8	A0A151NFX0	Differentially expressed in FDCP 8-like protein.	DUF4206 domain-containing protein.	0.923
ITGB3-2	SPP1	A0A151PBV2	A0A151NNL8	Integrin beta; Belongs to the integrin beta chain family.	Osteopontin.	0.970
ITGB3-2	SYK-2	A0A151PBV2	A0A151M807	Integrin beta; Belongs to the integrin beta chain family.	Tyrosine-protein kinase.	0.681
SPP1	ITGB3-2	A0A151NNL8	A0A151PBV2	Osteopontin.	Integrin beta; Belongs to the integrin beta chain family.	0.970
SPP1	TNFSF11	A0A151NNL8	A0A151MHR5	Osteopontin.	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	0.402
SYK-2	ITGB3-2	A0A151M807	A0A151PBV2	Tyrosine-protein kinase.	Integrin beta; Belongs to the integrin beta chain family.	0.681
TNFRSF11A	DCSTAMP	A0A151NFD7	A0A151MXT9	Tumor necrosis factor receptor superfamily member 11A.	Dendritic cell-specific transmembrane protein.	0.490
TNFRSF11A	TNFSF11	A0A151NFD7	A0A151MHR5	Tumor necrosis factor receptor superfamily member 11A.	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	0.998
TNFSF11	DCSTAMP	A0A151MHR5	A0A151MXT9	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	Dendritic cell-specific transmembrane protein.	0.625
TNFSF11	SPP1	A0A151MHR5	A0A151NNL8	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	Osteopontin.	0.402
TNFSF11	TNFRSF11A	A0A151MHR5	A0A151NFD7	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily member 11A.	0.998
Y1Q_0021150	DEF8	A0A151NFX0	A0A151NJW8	DUF4206 domain-containing protein.	Differentially expressed in FDCP 8-like protein.	0.923