(39 nodes) Synaptic vesicle endocytosis network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BIN1	Myc box-dependent-interacting protein 1 isoform A. (554 aa)
	SYNJ2	Uncharacterized protein. (1514 aa)
	Y1Q_0007531	BTB domain-containing protein. (1697 aa)
	STON2	Stonin-2 isoform B; Belongs to the Stoned B family. (910 aa)
	NLGN4X	Neuroligin-4, X-linked isoform B. (533 aa)
	Y1Q_0010673	COesterase domain-containing protein. (237 aa)
	SH3GL3	Endophilin-A3. (353 aa)
	SYNJ1	PAX3-and PAX7-binding protein 1. (2276 aa)
	ITSN1-2	Uncharacterized protein. (492 aa)
	DNM3	Dynamin-3 isoform C; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (915 aa)
	DENND1A	UDENN domain-containing protein. (818 aa)
	Y1Q_0019411	COesterase domain-containing protein. (181 aa)
	SNCG	Gamma-synuclein; Belongs to the synuclein family. (132 aa)
	SNAP91	Clathrin coat assembly protein AP180 isoform A. (857 aa)
	Y1Q_0011409	Basic proline-rich protein-like. (131 aa)
	LRRC1	Leucine-rich repeat-containing protein 1 isoform G. (1689 aa)
	SH3GL1	Uncharacterized protein. (367 aa)
	SYT2	Synaptotagmin-2. (398 aa)
	Y1Q_0004744	Protein kinase domain-containing protein. (161 aa)
	GAK	Cyclin-G-associated kinase isoform A. (878 aa)
	SYT5-2	Uncharacterized protein. (451 aa)
	PICALM-2	ENTH domain-containing protein. (609 aa)
	PICALM	Phosphatidylinositol-binding clathrin assembly protein isoform A. (669 aa)
	SNCA	Alpha-synuclein; Belongs to the synuclein family. (119 aa)
	DNM3-2	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (860 aa)
	DNM2	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (858 aa)
	STON1	Stonin-1; Belongs to the Stoned B family. (448 aa)
	NLGN4X-2	COesterase domain-containing protein. (812 aa)
	PACSIN1-2	Uncharacterized protein. (445 aa)
	SNCB	Beta-synuclein; Belongs to the synuclein family. (97 aa)
	SH3GL2	Endophilin-A1 isoform A. (352 aa)
	ITSN1	Intersectin-1. (1767 aa)
	Y1Q_0000001	COesterase domain-containing protein. (130 aa)
	SYT5	Synaptotagmin-5 isoform B. (426 aa)
	ADAD1-1	Adenosine deaminase domain-containing protein 1 isoform A. (5045 aa)
	LRRC1-2	Uncharacterized protein. (798 aa)
	NLGN2	COesterase domain-containing protein. (826 aa)
	NLGN3	COesterase domain-containing protein. (610 aa)
	AMPH	Amphiphysin isoform B. (1314 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMPH	DNM2	A0A151P2M6	A0A151NUQ9	Amphiphysin isoform B.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.453
AMPH	DNM3	A0A151P2M6	A0A151MFE1	Amphiphysin isoform B.	Dynamin-3 isoform C; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.453
AMPH	DNM3-2	A0A151P2M6	A0A151NTM6	Amphiphysin isoform B.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.453
AMPH	ITSN1	A0A151P2M6	A0A151PII8	Amphiphysin isoform B.	Intersectin-1.	0.608
AMPH	ITSN1-2	A0A151P2M6	A0A151ME63	Amphiphysin isoform B.	Uncharacterized protein.	0.491
AMPH	SYNJ1	A0A151P2M6	A0A151ME17	Amphiphysin isoform B.	PAX3-and PAX7-binding protein 1.	0.451
AMPH	SYNJ2	A0A151P2M6	A0A151M289	Amphiphysin isoform B.	Uncharacterized protein.	0.414
BIN1	DNM2	A0A151M138	A0A151NUQ9	Myc box-dependent-interacting protein 1 isoform A.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.456
BIN1	DNM3	A0A151M138	A0A151MFE1	Myc box-dependent-interacting protein 1 isoform A.	Dynamin-3 isoform C; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.455
BIN1	DNM3-2	A0A151M138	A0A151NTM6	Myc box-dependent-interacting protein 1 isoform A.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.456
BIN1	ITSN1	A0A151M138	A0A151PII8	Myc box-dependent-interacting protein 1 isoform A.	Intersectin-1.	0.608
BIN1	ITSN1-2	A0A151M138	A0A151ME63	Myc box-dependent-interacting protein 1 isoform A.	Uncharacterized protein.	0.491
BIN1	PICALM	A0A151M138	A0A151NNA6	Myc box-dependent-interacting protein 1 isoform A.	Phosphatidylinositol-binding clathrin assembly protein isoform A.	0.558
BIN1	PICALM-2	A0A151M138	A0A151NMC7	Myc box-dependent-interacting protein 1 isoform A.	ENTH domain-containing protein.	0.558
BIN1	SYNJ1	A0A151M138	A0A151ME17	Myc box-dependent-interacting protein 1 isoform A.	PAX3-and PAX7-binding protein 1.	0.451
BIN1	SYNJ2	A0A151M138	A0A151M289	Myc box-dependent-interacting protein 1 isoform A.	Uncharacterized protein.	0.414
DENND1A	ITSN1	A0A151MGG9	A0A151PII8	UDENN domain-containing protein.	Intersectin-1.	0.430
DNM2	AMPH	A0A151NUQ9	A0A151P2M6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Amphiphysin isoform B.	0.453
DNM2	BIN1	A0A151NUQ9	A0A151M138	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Myc box-dependent-interacting protein 1 isoform A.	0.456
DNM2	DNM3-2	A0A151NUQ9	A0A151NTM6	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.901