STRINGSTRING
A1CF A1CF WDR81 WDR81 PARK7 PARK7 ATF7IP ATF7IP MARCH7 MARCH7 PARK2 PARK2 PARK2L PARK2L PLPP3 PLPP3 APOA2 APOA2 USP5 USP5 CAMLG CAMLG CD74 CD74 PPIB PPIB FLOT2 FLOT2 MDM4 MDM4 TRIM44 TRIM44 PEX6 PEX6 MORC3 MORC3 WRB WRB TSC1 TSC1 DNLZ DNLZ CCT4 CCT4 COG3 COG3 SUGT1 SUGT1 NAA16 NAA16 MUL1 MUL1 OTUD3-1 OTUD3-1 PINK1 PINK1 MTMR9 MTMR9 EFNA1 EFNA1 HPS4 HPS4 CHP1 CHP1 MTMR9-2 MTMR9-2 ATP1B2 ATP1B2 TP53 TP53 SMAD7 SMAD7 STK4 STK4 GLTSCR2 GLTSCR2 FLOT1 FLOT1 CDC37 CDC37 USP7 USP7 STXBP4 STXBP4 ZNF207-1 ZNF207-1 SAV1 SAV1 TMEM88B TMEM88B TESC TESC CLU CLU FBXW9 FBXW9 TELO2 TELO2 NLK NLK Im:7160594 Im:7160594 FBXW7 FBXW7 PIM1 PIM1 CREB1 CREB1 ZSWIM7 ZSWIM7 Y1Q_0008844 Y1Q_0008844 ATP1B3 ATP1B3 PDCD10 PDCD10 MFSD1 MFSD1 TTI2 TTI2 BAG4 BAG4 Y1Q_0017188 Y1Q_0017188 CCT5 CCT5 CLUL1 CLUL1 USP19 USP19 CRYAB CRYAB TSPAN1 TSPAN1 CREBBP CREBBP Y1Q_0024039 Y1Q_0024039 NAA15 NAA15 CHEK2 CHEK2 LAMP2-1 LAMP2-1 TAF9B TAF9B SMO SMO CRYAA CRYAA HIP1R-2 HIP1R-2 HIP1R HIP1R BAG3 BAG3 PIN1 PIN1 PEX19-1 PEX19-1 COG7 COG7 BAG6 BAG6 LAMP1 LAMP1 CCT3 CCT3 GLMP GLMP STK4-2 STK4-2 Y1Q_0002793 Y1Q_0002793 NCLN NCLN SAXO1 SAXO1 BMP2K BMP2K PHB PHB CREBL2 CREBL2 BAG5 BAG5 WFS1 WFS1 MSX1 MSX1 FBXW7-2 FBXW7-2 GRN-1 GRN-1 GTPBP4 GTPBP4 BAG2 BAG2 Y1Q_0013170 Y1Q_0013170 TMEM19 TMEM19 CCT2 CCT2 RAB21 RAB21 WIZ WIZ CDK7 CDK7 CCNH CCNH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A1CFAPOBEC1 complementation factor isoform A. (595 aa)
WDR81WD repeat-containing protein 81. (1715 aa)
PARK7Protein deglycase DJ-1. (159 aa)
ATF7IPActivating transcription factor 7-interacting protein 1 isoform A. (1086 aa)
MARCH7E3 ubiquitin-protein ligase MARCH7. (590 aa)
PARK2E3 ubiquitin-protein ligase parkin isoform A. (280 aa)
PARK2LRBR-type E3 ubiquitin transferase. (180 aa)
PLPP3Lipid phosphate phosphohydrolase 3. (314 aa)
APOA2Apolipoprotein A-II. (115 aa)
USP5Ubiquitin carboxyl-terminal hydrolase. (875 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (257 aa)
CD74HLA class II histocompatibility antigen gamma chain; Belongs to the universal ribosomal protein uS11 family. (513 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (233 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (451 aa)
MDM4Protein Mdm4. (513 aa)
TRIM44Tripartite motif-containing protein 44. (131 aa)
PEX6Peroxisome biogenesis factor 6. (770 aa)
MORC3MORC family CW-type zinc finger protein 3. (938 aa)
WRBTail-anchored protein insertion receptor WRB. (170 aa)
TSC1Hamartin isoform B. (1115 aa)
DNLZDNL-type zinc finger protein. (265 aa)
CCT4T-complex protein 1 subunit delta. (537 aa)
COG3Conserved oligomeric Golgi complex subunit 3. (823 aa)
SUGT1SGT1-like protein. (328 aa)
NAA16Uncharacterized protein. (865 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (355 aa)
OTUD3-1OTU domain-containing protein 3 isoform B. (433 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the arginase family. (851 aa)
MTMR9Myotubularin-related protein 9 isoform A. (530 aa)
EFNA1Ephrin-A1; Belongs to the ephrin family. (205 aa)
HPS4Hermansky-Pudlak syndrome 4 protein. (698 aa)
CHP1Calcineurin B-like proteinous protein 1. (195 aa)
MTMR9-2Myotubularin phosphatase domain-containing protein. (550 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta-2. (209 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
SMAD7Mothers against decapentaplegic homolog. (384 aa)
STK4Serine/threonine-protein kinase 4. (490 aa)
GLTSCR2Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (409 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (501 aa)
CDC37Hsp90 co-chaperone Cdc37. (376 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1080 aa)
STXBP4Syntaxin-binding protein 4. (681 aa)
ZNF207-1BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform A. (467 aa)
SAV1Salvador-like protein 1. (391 aa)
TMEM88BTransmembrane protein 88B. (179 aa)
TESCCalcineurin B-like proteinous protein 3. (214 aa)
CLUClusterin; Belongs to the clusterin family. (467 aa)
FBXW9F-box/WD repeat-containing protein 9. (457 aa)
TELO2Telomere length regulation TEL2-like protein isoform B. (774 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (524 aa)
Im:7160594Major facilitator superfamily domain-containing protein 1. (511 aa)
FBXW7F-box/WD repeat-containing protein 7. (665 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
ZSWIM7Zinc finger SWIM domain-containing protein 7. (161 aa)
Y1Q_0008844Uncharacterized protein. (90 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
PDCD10Programmed cell death protein 10. (225 aa)
MFSD1Major facilitator superfamily domain-containing protein 1 isoform A. (520 aa)
TTI2TELO2-interacting protein 2. (510 aa)
BAG4BAG family molecular chaperone regulator 4. (387 aa)
Y1Q_0017188Uncharacterized protein. (164 aa)
CCT5T-complex protein 1 subunit epsilon. (541 aa)
CLUL1Clusterin; Belongs to the clusterin family. (435 aa)
USP19Ubiquitin carboxyl-terminal hydrolase 19 isoform A. (1473 aa)
CRYABAlpha-crystallin B chain isoform A; Belongs to the small heat shock protein (HSP20) family. (174 aa)
TSPAN1Tetraspanin. (239 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
NAA15N-alpha-acetyltransferase 15, NatA auxiliary subunit. (865 aa)
CHEK2Serine/threonine-protein kinase Chk2 isoform B. (433 aa)
LAMP2-1Lysosome-associated membrane glycoprotein 2 isoform C. (470 aa)
TAF9BTranscription initiation factor TFIID subunit 9B. (255 aa)
SMOSmoothened-like protein; Belongs to the G-protein coupled receptor Fz/Smo family. (804 aa)
CRYAAAlpha-crystallin A chain; Belongs to the small heat shock protein (HSP20) family. (115 aa)
HIP1R-2Uncharacterized protein. (1065 aa)
HIP1RHuntingtin-interacting protein 1-related protein isoform A. (1040 aa)
BAG3BAG family molecular chaperone regulator 3. (552 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (159 aa)
PEX19-1Peroxisomal biogenesis factor 19 isoform B. (290 aa)
COG7Conserved oligomeric Golgi complex subunit 7. (769 aa)
BAG6Large proline-rich protein BAG6. (945 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (420 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
GLMPGlycosylated lysosomal membrane protein. (392 aa)
STK4-2Protein kinase domain-containing protein. (416 aa)
Y1Q_0002793SARAH domain-containing protein. (108 aa)
NCLNNicalin. (513 aa)
SAXO1Stabilizer of axonemal microtubules 1. (489 aa)
BMP2KBMP-2-inducible protein kinase isoform B. (1003 aa)
PHBProhibitin. (273 aa)
CREBL2cAMP-responsive element-binding protein-like 2 isoform B. (139 aa)
BAG5BAG family molecular chaperone regulator 5. (450 aa)
WFS1Wolframin. (387 aa)
MSX1Homeobox protein MSX-1. (256 aa)
FBXW7-2Uncharacterized protein. (674 aa)
GRN-1Granulins isoform B. (1084 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (633 aa)
BAG2BAG family molecular chaperone regulator 2. (208 aa)
Y1Q_0013170Uncharacterized protein. (100 aa)
TMEM19Transmembrane protein 19. (336 aa)
CCT2T-complex protein 1 subunit beta. (535 aa)
RAB21Ras-related protein Rab-21. (217 aa)
WIZProtein Wiz isoform A. (1906 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
CCNHCyclin-H; Belongs to the cyclin family. (247 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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