STRINGSTRING
FXN FXN Y1Q_0005511 Y1Q_0005511 SDHB SDHB CIAPIN1 CIAPIN1 FECH FECH FDX1L FDX1L UQCRFS1 UQCRFS1 NDUFS1 NDUFS1 Y1Q_0008776 Y1Q_0008776 Y1Q_0008774 Y1Q_0008774 Y1Q_0008775 Y1Q_0008775 AOX1 AOX1 Y1Q_0008773 Y1Q_0008773 NDUFV2 NDUFV2 AIFM3 AIFM3 ISCA2 ISCA2 CISD2 CISD2 FDX1LL FDX1LL ISCU ISCU BOLA2B BOLA2B CISD1 CISD1 AIFM3L AIFM3L XDH XDH CISD3 CISD3 FDX1-1 FDX1-1 RFESD RFESD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FXNFrataxin, mitochondrial. (173 aa)
Y1Q_0005511Cholesterol 7-desaturase-like. (330 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (277 aa)
CIAPIN1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (275 aa)
FECHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (412 aa)
FDX1LAdrenodoxin-like protein, mitochondrial. (172 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (278 aa)
NDUFS1NADH-ubiquinone oxidoreductase subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (766 aa)
Y1Q_0008776Uncharacterized protein. (1147 aa)
Y1Q_0008774FAD-binding PCMH-type domain-containing protein. (748 aa)
Y1Q_0008775Uncharacterized protein. (1345 aa)
AOX1Uncharacterized protein. (1421 aa)
Y1Q_0008773Uncharacterized protein. (1231 aa)
NDUFV2NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. (245 aa)
AIFM3Apoptosis-inducing factor 3 isoform A. (598 aa)
ISCA2Iron-sulfur cluster assembly 2-like protein, mitochondrial. (117 aa)
CISD2CDGSH iron-sulfur domain-containing protein 2. (135 aa)
FDX1LLAdrenodoxin. (191 aa)
ISCUIron-sulfur cluster assembly enzyme ISCU, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (153 aa)
BOLA2BBolA-like protein 2; Belongs to the BolA/IbaG family. (85 aa)
CISD1CDGSH iron-sulfur domain-containing protein 1. (108 aa)
AIFM3LApoptosis-inducing factor 3. (556 aa)
XDHXanthine dehydrogenase/oxidase. (1359 aa)
CISD3CDGSH iron-sulfur domain-containing protein 3, mitochondrial isoform B. (126 aa)
FDX1-1Adrenodoxin, mitochondrial isoform B. (207 aa)
RFESDRieske domain-containing protein isoform A. (188 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (38%) [HD]