STRINGSTRING
CCL4 CCL4 BIN2 BIN2 NR4A1 NR4A1 RHOG RHOG LGALS3 LGALS3 CCR6 CCR6 CXCL14 CXCL14 PDGFRA PDGFRA GAB1 GAB1 SLAMF1 SLAMF1 SYK-2 SYK-2 ANXA1 ANXA1 IL16 IL16 PPIB PPIB MDK MDK Y1Q_0002953 Y1Q_0002953 XCL1 XCL1 CXADR CXADR VEGFA-1 VEGFA-1 TNFSF11 TNFSF11 LEF1 LEF1 EPHA2 EPHA2 Y1Q_0023273 Y1Q_0023273 FAM19A4 FAM19A4 CRK CRK CXCL12 CXCL12 Y1Q_0005880 Y1Q_0005880 Y1Q_0005879 Y1Q_0005879 CXCL10 CXCL10 Y1Q_0012275 Y1Q_0012275 CYP7B1 CYP7B1 CXCL13 CXCL13 CXCL8 CXCL8 CCL17 CCL17 CX3CL1 CX3CL1 FLT1-2 FLT1-2 BCAR1 BCAR1 SLC37A4 SLC37A4 ITGA1 ITGA1 CCL28 CCL28 NOV NOV NUP85 NUP85 ARHGEF16 ARHGEF16 CXCL8A CXCL8A CXCL8-2 CXCL8-2 CXCL11 CXCL11 IL8L1 IL8L1 Y1Q_0013039 Y1Q_0013039 Y1Q_0013038 Y1Q_0013038 CKLF CKLF CCL1 CCL1 CCL21 CCL21 PIKFYVE PIKFYVE ACKR3 ACKR3 CCL20 CCL20 SCG2 SCG2 LPAR1 LPAR1 TRPM5 TRPM5 PDGFB PDGFB PTN PTN IL17RA IL17RA PTPRO PTPRO SRP54 SRP54 EDNRB EDNRB TNFSF14 TNFSF14 MSMP MSMP Y1Q_0015586 Y1Q_0015586 PRKCQ PRKCQ HGF HGF HBEGF-1 HBEGF-1 CCL38A.5 CCL38A.5 FFAR2 FFAR2 Y1Q_0013293 Y1Q_0013293 Y1Q_0013292 Y1Q_0013292 GAS6 GAS6 CXCL8-3 CXCL8-3 CXCR5 CXCR5 ITGA9 ITGA9 CXCR1 CXCR1 Y1Q_0004713 Y1Q_0004713 HOXB9-1 HOXB9-1 ARHGEF5 ARHGEF5 Y1Q_0007371 Y1Q_0007371 KIT-2 KIT-2 PRKCD PRKCD CCR10 CCR10 CCR7 CCR7 NRP2 NRP2 ACKR2 ACKR2 DOCK4 DOCK4 ANO6 ANO6 AMICA1 AMICA1 CSF3R CSF3R EDN2 EDN2 GBF1 GBF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCL4C-C motif chemokine. (91 aa)
BIN2Bridging integrator 2. (852 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (579 aa)
RHOGRho-related GTP-binding protein RhoG. (191 aa)
LGALS3Galectin. (167 aa)
CCR6Uncharacterized protein. (97 aa)
CXCL14C-X-C motif chemokine 14. (97 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1097 aa)
GAB1GRB2-associated-binding protein 1 isoform A. (720 aa)
SLAMF1Signaling lymphocytic activation molecule. (331 aa)
SYK-2Tyrosine-protein kinase. (608 aa)
ANXA1Annexin. (362 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1474 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (233 aa)
MDKMidkine. (156 aa)
Y1Q_0002953Uncharacterized protein. (68 aa)
XCL1Lymphotactin. (192 aa)
CXADRCoxsackievirus and adenovirus receptor. (355 aa)
VEGFA-1Vascular endothelial growth factor A isoform A; Belongs to the PDGF/VEGF growth factor family. (216 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (271 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform B. (391 aa)
EPHA2Uncharacterized protein. (979 aa)
Y1Q_0023273Uncharacterized protein. (599 aa)
FAM19A4Protein FAM19A4. (162 aa)
CRKAdapter molecule crk. (291 aa)
CXCL12Stromal cell-derived factor 1; Belongs to the intercrine alpha (chemokine CxC) family. (93 aa)
Y1Q_0005880Free fatty acid receptor 2-like; Belongs to the G-protein coupled receptor 1 family. (355 aa)
Y1Q_0005879G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (322 aa)
CXCL10C-X-C motif chemokine 10. (99 aa)
Y1Q_0012275C-X-C motif chemokine 10-like. (100 aa)
CYP7B125-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
CXCL13Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CXCL8Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa)
CCL17C-C motif chemokine. (137 aa)
CX3CL1Fractalkine. (118 aa)
FLT1-2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1333 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1. (960 aa)
SLC37A4Glucose-6-phosphate translocase. (429 aa)
ITGA1VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1137 aa)
CCL28C-C motif chemokine 28. (124 aa)
NOVNOV-like protein. (252 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (620 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (628 aa)
CXCL8AInterleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (93 aa)
CXCL8-2Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
CXCL11C-X-C motif chemokine. (83 aa)
IL8L1Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
Y1Q_0013039C-C motif chemokine. (90 aa)
Y1Q_0013038C-C motif chemokine. (90 aa)
CKLFChemokine-like factor. (139 aa)
CCL1Chemokine (C-C motif) ligand 1. (96 aa)
CCL21SCY domain-containing protein. (93 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform A. (2159 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (364 aa)
CCL20C-C motif chemokine. (86 aa)
SCG2Secretogranin-2. (681 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1476 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (234 aa)
PTNPleiotrophin. (165 aa)
IL17RAInterleukin-17 receptor A. (832 aa)
PTPROReceptor-type tyrosine-protein phosphatase O isoform B. (1189 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (548 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (383 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14; Belongs to the tumor necrosis factor family. (236 aa)
MSMPProstate-associated microseminoprotein. (137 aa)
Y1Q_0015586Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1335 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (751 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (723 aa)
HBEGF-1Proheparin-binding EGF-like growth factor isoform B. (205 aa)
CCL38A.5SCY domain-containing protein. (83 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (322 aa)
Y1Q_0013293C-C motif chemokine. (102 aa)
Y1Q_0013292C-C motif chemokine 5-like. (91 aa)
GAS6Growth arrest-specific protein 6. (676 aa)
CXCL8-3Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
CXCR5C-X-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (356 aa)
ITGA9Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1002 aa)
CXCR1C-X-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (615 aa)
Y1Q_0004713C-C motif chemokine 19-like. (72 aa)
HOXB9-1Homeobox protein Hox-B9 isoform A. (255 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5 isoform B. (1796 aa)
Y1Q_0007371G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (437 aa)
KIT-2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (947 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
CCR10C-C chemokine receptor type 10; Belongs to the G-protein coupled receptor 1 family. (365 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (376 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (925 aa)
ACKR2Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (366 aa)
DOCK4Uncharacterized protein; Belongs to the DOCK family. (1959 aa)
ANO6Anoctamin. (930 aa)
AMICA1Junctional adhesion molecule-like. (277 aa)
CSF3RGranulocyte colony-stimulating factor receptor. (916 aa)
EDN2Endothelin-2. (181 aa)
GBF1Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform C. (1865 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.