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SOX18 | Transcription factor SOX-18. (392 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) | ||||
PDCD2 | Programmed cell death protein 2. (311 aa) | ||||
CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (170 aa) | ||||
PTCH1 | Patched-like protein 1. (1479 aa) | ||||
ATXN1L | Ataxin-1-like. (603 aa) | ||||
FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa) | ||||
FERMT1 | PH domain-containing protein. (628 aa) | ||||
EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase. (532 aa) | ||||
NR2E1 | Nuclear receptor subfamily 2 group E member 1. (385 aa) | ||||
TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (730 aa) | ||||
SOX17 | Sox C-terminal domain-containing protein. (232 aa) | ||||
N4BP2L2 | NEDD4-binding protein 2-like 2 isoform A. (768 aa) | ||||
TGFBR2-2 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (546 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa) | ||||
NF2 | Merlin isoform A. (593 aa) | ||||
Y1Q_0007089 | FERM domain-containing protein. (665 aa) | ||||
NF1 | Neurofibromin isoform B. (2879 aa) | ||||
CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (408 aa) | ||||
PTPRC | Receptor-type tyrosine-protein phosphatase C isoform D. (1209 aa) | ||||
TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (599 aa) | ||||
KDF1 | Keratinocyte differentiation factor 1. (401 aa) | ||||
NPM3 | Nucleoplasmin-3; Belongs to the heparin-binding growth factors family. (345 aa) | ||||
DGCR8 | Microprocessor complex subunit DGCR8. (775 aa) | ||||
SIRT6 | NAD-dependent protein deacetylase sirtuin-6. (357 aa) | ||||
TGFB1 | TGF_BETA_2 domain-containing protein. (242 aa) | ||||
GLI3 | Uncharacterized protein. (1572 aa) | ||||
FBLN1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (713 aa) | ||||
KDR | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1353 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (414 aa) | ||||
FERMT2 | Fermitin family-like protein 2. (680 aa) | ||||
HMGA2 | High mobility group protein HMGI-C. (112 aa) | ||||
ZMPSTE24 | CAAX prenyl protease 1-like protein. (1233 aa) |