31 items (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	DR1	Protein Dr1. (176 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial; Belongs to the arginase family. (851 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (527 aa)
	JDP2	Jun dimerization protein 2. (173 aa)
	SDR16C5-1	Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (281 aa)
	Y1Q_0003831	Epidermal retinol dehydrogenase 2-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (254 aa)
	SDR16C5-2	Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (367 aa)
	SPRED1	Sprouty-related, EVH1 domain-containing protein 1. (314 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
	NIPBL	Nipped-B protein. (2617 aa)
	PRKAA1-2	Non-specific serine/threonine protein kinase. (547 aa)
	SAP30BP	SAP30-binding protein. (311 aa)
	TADA2A	Transcriptional adapter. (525 aa)
	RRP8	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (108 aa)
	CSRP2BP	Cysteine-rich protein 2-binding protein. (778 aa)
	FNTA	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha isoform B. (380 aa)
	CREBBP	CREB-binding protein isoform C. (2208 aa)
	Y1Q_0024039	KIX domain-containing protein. (131 aa)
	KDM5A	Uncharacterized protein. (1692 aa)
	ZZZ3	ZZ-type zinc finger-containing protein 3 isoform B. (951 aa)
	MBIP-1	MAP3K12-binding inhibitory protein 1 isoform B. (276 aa)
	LRRK2	Leucine-rich repeat serine/threonine-protein kinase 2. (2528 aa)
	YEATS2	YEATS domain-containing protein 2 isoform A. (1403 aa)
	TGFB1	TGF_BETA_2 domain-containing protein. (242 aa)
	SIRT1	NAD-dependent protein deacetylase sirtuin-1. (634 aa)
	CCDC101	SAGA-associated factor 29-like protein. (357 aa)
	ING2	Inhibitor of growth protein. (228 aa)
	NCAPG2	Condensin-2 complex subunit G2. (1146 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (125 aa)
	AKAP8	A-kinase anchor protein 8 isoform B; Belongs to the AKAP95 family. (669 aa)
	TPPP	Tubulin polymerization-promoting protein. (231 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC101	CSRP2BP	A0A151P1L9	A0A151ND88	SAGA-associated factor 29-like protein.	Cysteine-rich protein 2-binding protein.	0.989
CCDC101	DR1	A0A151P1L9	A0A151M4Z2	SAGA-associated factor 29-like protein.	Protein Dr1.	0.860
CCDC101	MBIP-1	A0A151P1L9	A0A151NKB6	SAGA-associated factor 29-like protein.	MAP3K12-binding inhibitory protein 1 isoform B.	0.789
CCDC101	TADA2A	A0A151P1L9	A0A151N5V1	SAGA-associated factor 29-like protein.	Transcriptional adapter.	0.993
CCDC101	YEATS2	A0A151P1L9	A0A151NU28	SAGA-associated factor 29-like protein.	YEATS domain-containing protein 2 isoform A.	0.936
CCDC101	ZZZ3	A0A151P1L9	A0A151NJ96	SAGA-associated factor 29-like protein.	ZZ-type zinc finger-containing protein 3 isoform B.	0.988
CREBBP	ING2	A0A151NHH3	A0A151PAK8	CREB-binding protein isoform C.	Inhibitor of growth protein.	0.652
CREBBP	SIRT1	A0A151NHH3	A0A151P0R7	CREB-binding protein isoform C.	NAD-dependent protein deacetylase sirtuin-1.	0.563
CREBBP	TGFB1	A0A151NHH3	A0A151P039	CREB-binding protein isoform C.	TGF_BETA_2 domain-containing protein.	0.467
CREBBP	TP53	A0A151NHH3	A0A151MW63	CREB-binding protein isoform C.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.993
CSRP2BP	CCDC101	A0A151ND88	A0A151P1L9	Cysteine-rich protein 2-binding protein.	SAGA-associated factor 29-like protein.	0.989
CSRP2BP	DR1	A0A151ND88	A0A151M4Z2	Cysteine-rich protein 2-binding protein.	Protein Dr1.	0.918
CSRP2BP	MBIP-1	A0A151ND88	A0A151NKB6	Cysteine-rich protein 2-binding protein.	MAP3K12-binding inhibitory protein 1 isoform B.	0.788
CSRP2BP	TADA2A	A0A151ND88	A0A151N5V1	Cysteine-rich protein 2-binding protein.	Transcriptional adapter.	0.873
CSRP2BP	YEATS2	A0A151ND88	A0A151NU28	Cysteine-rich protein 2-binding protein.	YEATS domain-containing protein 2 isoform A.	0.952
CSRP2BP	ZZZ3	A0A151ND88	A0A151NJ96	Cysteine-rich protein 2-binding protein.	ZZ-type zinc finger-containing protein 3 isoform B.	0.951
DR1	CCDC101	A0A151M4Z2	A0A151P1L9	Protein Dr1.	SAGA-associated factor 29-like protein.	0.860
DR1	CSRP2BP	A0A151M4Z2	A0A151ND88	Protein Dr1.	Cysteine-rich protein 2-binding protein.	0.918
DR1	MBIP-1	A0A151M4Z2	A0A151NKB6	Protein Dr1.	MAP3K12-binding inhibitory protein 1 isoform B.	0.865
DR1	TADA2A	A0A151M4Z2	A0A151N5V1	Protein Dr1.	Transcriptional adapter.	0.893