STRINGSTRING
DECR1 DECR1 CNOT3-2 CNOT3-2 CNOT3-1 CNOT3-1 OMA1 OMA1 TSHR TSHR DIO2 DIO2 ADIPOQ ADIPOQ PPARGC1B PPARGC1B ADRB2 ADRB2 SYK-2 SYK-2 GADD45G GADD45G Y1Q_0024399 Y1Q_0024399 LRRN4CL LRRN4CL DBH DBH ELOVL6 ELOVL6 HADH HADH G0S2 G0S2 GHRL-1 GHRL-1 CAV3 CAV3 FABP5 FABP5 LEP LEP OXT OXT ALMS1 ALMS1 IL4R IL4R YBX2-1 YBX2-1 Y1Q_0014316 Y1Q_0014316 PEMT PEMT CCDC115 CCDC115 PRDM16 PRDM16 MFN2-2 MFN2-2 KDM6B-2 KDM6B-2 LPIN1 LPIN1 ADIPOR2L ADIPOR2L TRPV2-2 TRPV2-2 ADRB3 ADRB3 BSCL2 BSCL2 ZNF516 ZNF516 IL18 IL18 APPL2 APPL2 ADIPOR2 ADIPOR2 LEPR-1 LEPR-1 FGF21 FGF21 CMKLR1 CMKLR1 PRKAB2-1 PRKAB2-1 OGT OGT ADRB1 ADRB1 EPAS1 EPAS1 SIRT6 SIRT6 CEBPB CEBPB PLACL2 PLACL2 FFAR4 FFAR4 DYNC1H1 DYNC1H1 PPARGC1A PPARGC1A PHOX2B PHOX2B PDGFC PDGFC HCRT HCRT CAV1 CAV1 ZMPSTE24 ZMPSTE24
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DECR12,4-dienoyl-CoA reductase, mitochondrial. (336 aa)
CNOT3-2CCR4-NOT transcription complex subunit 3. (264 aa)
CNOT3-1CCR4-NOT transcription complex subunit 3. (456 aa)
OMA1Metalloendopeptidase OMA1, mitochondrial. (504 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (750 aa)
DIO2Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (78 aa)
ADIPOQAdiponectin. (263 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform A. (1037 aa)
ADRB2Beta-2 adrenergic receptor. (392 aa)
SYK-2Tyrosine-protein kinase. (608 aa)
GADD45GGrowth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa)
Y1Q_0024399Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (342 aa)
LRRN4CLLRRN4 C-terminal-like protein. (261 aa)
DBHDopamine beta-hydroxylase. (598 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa)
HADHHydroxyacyl-coenzyme A dehydrogenase, mitochondrial. (277 aa)
G0S2G0/G1 switch protein 2. (160 aa)
GHRL-1Appetite-regulating hormone isoform B. (145 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
FABP5Fatty acid binding protein 5 (Psoriasis-associated); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (168 aa)
OXTNeurophysin 1; Belongs to the vasopressin/oxytocin family. (124 aa)
ALMS1Alstrom syndrome protein 1. (2793 aa)
IL4RInterleukin-4 receptor subunit alpha. (1223 aa)
YBX2-1Y-box-binding protein 2 isoform B. (373 aa)
Y1Q_0014316Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PEMTPhosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (232 aa)
CCDC115Coiled-coil domain-containing protein 115 isoform B. (475 aa)
PRDM16Uncharacterized protein. (1167 aa)
MFN2-2Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (737 aa)
KDM6B-2Uncharacterized protein. (1393 aa)
LPIN1Phosphatidate phosphatase LPIN1 isoform B. (975 aa)
ADIPOR2LAdiponectin receptor protein 2. (375 aa)
TRPV2-2ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (773 aa)
ADRB3Beta-3 adrenergic receptor. (439 aa)
BSCL2Seipin. (353 aa)
ZNF516Zinc finger protein 516 isoform A. (1299 aa)
IL18Interleukin-18. (239 aa)
APPL2Uncharacterized protein. (659 aa)
ADIPOR2Adiponectin receptor protein 2. (387 aa)
LEPR-1Leptin receptor isoform B. (528 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
CMKLR1Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (406 aa)
PRKAB2-15'-AMP-activated protein kinase subunit beta-2 isoform B. (274 aa)
OGTUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase subunit isoform B. (1075 aa)
ADRB1Beta-1 adrenergic receptor. (383 aa)
EPAS1Endothelial PAS domain-containing protein 1. (863 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6. (357 aa)
CEBPBCCAAT/enhancer-binding protein beta. (141 aa)
PLACL2Placenta-specific 8 protein-like. (132 aa)
FFAR4Free fatty acid receptor 4. (353 aa)
DYNC1H1Uncharacterized protein. (4633 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform A. (555 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (180 aa)
PDGFCPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (347 aa)
HCRTOrexin. (158 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ZMPSTE24CAAX prenyl protease 1-like protein. (1233 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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