STRINGSTRING
NFE2L2 NFE2L2 RBPJ RBPJ c-jun c-jun SMAD1 SMAD1 JUND JUND XBP1 XBP1 ATF4-1 ATF4-1 Y1Q_0024039 Y1Q_0024039 ATF4-2 ATF4-2 CREBBP CREBBP SESN2L SESN2L CARF CARF TP53 TP53 CREB3 CREB3 DLX5 DLX5 SMAD2 SMAD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NFE2L2Nuclear factor erythroid 2-related factor 2. (482 aa)
RBPJRecombining binding protein suppressor of hairless isoform B. (498 aa)
c-junTranscription factor AP-1; Belongs to the bZIP family. (320 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
JUNDBZIP domain-containing protein. (87 aa)
XBP1X-box-binding protein 1. (286 aa)
ATF4-1Cyclic AMP-dependent transcription factor ATF-4. (117 aa)
Y1Q_0024039KIX domain-containing protein. (131 aa)
ATF4-2Cyclic AMP-dependent transcription factor ATF-4. (124 aa)
CREBBPCREB-binding protein isoform C. (2208 aa)
SESN2LSestrin 2. (509 aa)
CARFCalcium-responsive transcription factor isoform A. (727 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (368 aa)
DLX5Homeobox protein DLX-5. (266 aa)
SMAD2Mothers against decapentaplegic homolog. (474 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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