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NDUFB8 NDUFB8 NDUFA1 NDUFA1 GCSH-1 GCSH-1 SDHC SDHC NCF4 NCF4 NDUFA6 NDUFA6 FOXRED1 FOXRED1 SDHD SDHD DLAT DLAT NDUFV2 NDUFV2 NDUFB6 NDUFB6 NDUFS6 NDUFS6 NDUFA7-1 NDUFA7-1 NDUFB7 NDUFB7 NDUFB3 NDUFB3 NDUFA10 NDUFA10 NDUFS1 NDUFS1 HSD17B8 HSD17B8 UQCRFS1 UQCRFS1 NDUFC2 NDUFC2 NDUFV1 NDUFV1 NDUFB10 NDUFB10 NOXO1 NOXO1 PDHA1 PDHA1 IDH3B IDH3B NDUFS4 NDUFS4 ETFB ETFB NOX4 NOX4 BCKDHB BCKDHB BCKDK BCKDK OGDHL-2 OGDHL-2 DLST DLST GPD1 GPD1 GPD1L GPD1L NDUFA4 NDUFA4 BCKDHA BCKDHA GMPR GMPR OGDHL OGDHL NDUFA13 NDUFA13 PDHB PDHB SDHB SDHB NCF2 NCF2 NDUFA8 NDUFA8 NOXA1 NOXA1 NDUFB4 NDUFB4 CAT CAT PDHX PDHX NDUFS3 NDUFS3 DUOX2 DUOX2 Y1Q_0001657 Y1Q_0001657 IDH3A IDH3A ETFA ETFA WDR93 WDR93 GLDC GLDC UQCRQ UQCRQ NDUFA12 NDUFA12 CYC1 CYC1 GPD2 GPD2 Y1Q_0011724 Y1Q_0011724 RRM1 RRM1 DBT DBT NDUFB5 NDUFB5 MRPS36 MRPS36 FH FH NDUFS7 NDUFS7 NDUFS2 NDUFS2 NDUFA5 NDUFA5 CBR4 CBR4 NDUFA9 NDUFA9 CYBA CYBA NDUFB11 NDUFB11 OR10W1 OR10W1 NDUFA2 NDUFA2 NDUFV3-1 NDUFV3-1 DLD DLD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (184 aa)
NDUFA1NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. (70 aa)
GCSH-1Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (169 aa)
SDHCSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial. (169 aa)
NCF4Neutrophil cytosol factor 4. (352 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (131 aa)
FOXRED1FAD-dependent oxidoreductase domain-containing protein 1. (458 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (163 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (544 aa)
NDUFV2NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. (245 aa)
NDUFB6NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6. (128 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial. (150 aa)
NDUFA7-1NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 isoform B. (223 aa)
NDUFB7NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. (126 aa)
NDUFB3NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (132 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (357 aa)
NDUFS1NADH-ubiquinone oxidoreductase subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (766 aa)
HSD17B8Estradiol 17-beta-dehydrogenase 8. (191 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (278 aa)
NDUFC2NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (110 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. (792 aa)
NDUFB10NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. (175 aa)
NOXO1NADPH oxidase organizer 1. (486 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (395 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit beta, mitochondrial. (255 aa)
NDUFS4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (165 aa)
ETFBElectron transfer flavoprotein subunit beta. (257 aa)
NOX4NADPH oxidase 4 isoform B. (628 aa)
BCKDHB2-oxoisovalerate dehydrogenase subunit beta, mitochondrial. (375 aa)
BCKDKProtein-serine/threonine kinase. (379 aa)
OGDHL-2Transket_pyr domain-containing protein. (1086 aa)
DLSTannotation not available (423 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (353 aa)
NDUFA4Cytochrome c oxidase subunit NDUFA4. (82 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (431 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (381 aa)
OGDHL2-oxoglutarate dehydrogenase-like, mitochondrial isoform B. (967 aa)
NDUFA13NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (144 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (270 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (277 aa)
NCF2Neutrophil cytosol factor 2 isoform A. (573 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (172 aa)
NOXA1NADPH oxidase activator 1 isoform B. (517 aa)
NDUFB4NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (134 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (505 aa)
NDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (246 aa)
DUOX2Dual oxidase 2. (1540 aa)
Y1Q_0001657Uncharacterized protein. (199 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
ETFAElectron transfer flavoprotein subunit alpha, mitochondrial. (334 aa)
WDR93WD repeat-containing protein 93. (686 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (943 aa)
UQCRQCytochrome b-c1 complex subunit 8. (82 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (146 aa)
CYC1Cytochrome c1, heme protein, mitochondrial. (312 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (745 aa)
Y1Q_0011724Glycerol-3-phosphate dehydrogenase [NAD(+)]. (366 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (779 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (495 aa)
NDUFB5NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial. (154 aa)
MRPS3628S ribosomal protein S36, mitochondrial. (107 aa)
FHSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (1165 aa)
NDUFS7NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Belongs to the complex I 20 kDa subunit family. (204 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. (455 aa)
NDUFA5NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa)
CBR4Carbonyl reductase family member 4. (237 aa)
NDUFA9NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial. (382 aa)
CYBACytochrome b-245 light chain. (171 aa)
NDUFB11NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. (93 aa)
OR10W1Olfactory receptor. (317 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (102 aa)
NDUFV3-1NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform B. (136 aa)
DLDDihydrolipoyl dehydrogenase. (508 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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