STRINGSTRING
TDP2 TDP2 MLIP-1 MLIP-1 RDM1 RDM1 PPARGC1A PPARGC1A RNF4 RNF4 ZMYM5 ZMYM5 CALCOCO2 CALCOCO2 ZBTB16 ZBTB16 TP53INP2 TP53INP2 Y1Q_0020201 Y1Q_0020201 PTEN PTEN TRIM16 TRIM16 TRIM8 TRIM8 Y1Q_0006676 Y1Q_0006676 ACRC-1 ACRC-1 CHFR CHFR CHEK2 CHEK2 HIPK2 HIPK2 SUMO3 SUMO3 TPTE2 TPTE2 ANKRD2 ANKRD2 SUMO1 SUMO1 DAXX DAXX Y1Q_0007761 Y1Q_0007761 RPAIN RPAIN CIITA-1 CIITA-1 TP53INP1-1 TP53INP1-1 TP53 TP53 CASP8AP2 CASP8AP2 BLM BLM RNF6 RNF6 N4BP1 N4BP1 KLHL20 KLHL20 MORC3 MORC3 PML PML RNF111-1 RNF111-1 RPA1 RPA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TDP2Tyrosyl-DNA phosphodiesterase 2. (363 aa)
MLIP-1Muscular LMNA-interacting protein isoform D. (544 aa)
RDM1RAD52 motif-containing protein 1. (275 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform A. (555 aa)
RNF4E3 ubiquitin-protein ligase RNF4. (194 aa)
ZMYM5Zinc finger MYM-type protein 5 isoform C. (833 aa)
CALCOCO2Calcium-binding and coiled-coil domain-containing protein 2 isoform B. (583 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16. (666 aa)
TP53INP2Tumor protein p53-inducible nuclear protein 2. (152 aa)
Y1Q_0020201DUF3504 domain-containing protein. (160 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
TRIM16Tripartite motif-containing protein 16. (558 aa)
TRIM8Putative E3 ubiquitin-protein ligase TRIM8. (551 aa)
Y1Q_0006676Uncharacterized protein. (1164 aa)
ACRC-1Acidic repeat-containing protein isoform B. (498 aa)
CHFRE3 ubiquitin-protein ligase CHFR isoform B. (679 aa)
CHEK2Serine/threonine-protein kinase Chk2 isoform B. (433 aa)
HIPK2Protein kinase domain-containing protein. (1175 aa)
SUMO3Small ubiquitin-related modifier. (94 aa)
TPTE2Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2. (511 aa)
ANKRD2Ankyrin repeat domain-containing protein 2. (266 aa)
SUMO1Small ubiquitin-related modifier. (93 aa)
DAXXDeath domain-associated protein 6 isoform A. (758 aa)
Y1Q_0007761Uncharacterized protein. (246 aa)
RPAINRPA-interacting protein. (217 aa)
CIITA-1MHC class II transactivator isoform A. (958 aa)
TP53INP1-1Tumor protein p53-inducible nuclear protein 1 isoform B. (225 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
CASP8AP2CASP8-associated protein 2. (1424 aa)
BLMBloom syndrome protein. (1213 aa)
RNF6Uncharacterized protein. (126 aa)
N4BP1NEDD4-binding protein 1. (938 aa)
KLHL20Kelch-like protein 20 isoform A. (711 aa)
MORC3MORC family CW-type zinc finger protein 3. (938 aa)
PMLProtein PML isoform B. (586 aa)
RNF111-1E3 ubiquitin-protein ligase Arkadia isoform A. (911 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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