(42 nodes) Tyrosine-specific protein phosphatase, PTPase domain network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTPRO	Receptor-type tyrosine-protein phosphatase O isoform B. (1189 aa)
	PTPRN-2	Uncharacterized protein. (281 aa)
	PTPN13	Tyrosine-protein phosphatase non-receptor type 13 isoform C. (2492 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (744 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	Y1Q_0015722	Receptor-type tyrosine-protein phosphatase T-like. (566 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (435 aa)
	PTPN3	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (939 aa)
	PTPRU	Uncharacterized protein. (1507 aa)
	PTPRQ	Phosphatidylinositol phosphatase PTPRQ isoform G. (5845 aa)
	PTPRR	Receptor-type tyrosine-protein phosphatase R. (2872 aa)
	PTPRZ1	Protein-tyrosine-phosphatase. (1295 aa)
	PTP4A1	Protein tyrosine phosphatase type IVA 1. (170 aa)
	PTPRN	Receptor-type tyrosine-protein phosphatase-like N. (422 aa)
	PTPN21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1181 aa)
	PTP4A3	Protein tyrosine phosphatase type IVA 3. (173 aa)
	PTPRT	Uncharacterized protein. (1414 aa)
	PTPRS	Uncharacterized protein. (1911 aa)
	PTPN14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1182 aa)
	PTPN4	Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (953 aa)
	PTPRM	Receptor-type tyrosine-protein phosphatase mu isoform C. (1440 aa)
	Y1Q_0015214	Uncharacterized protein. (749 aa)
	PTPRA	Receptor-type tyrosine-protein phosphatase alpha isoform A. (1898 aa)
	PTPN9	Tyrosine-protein phosphatase non-receptor type 9. (584 aa)
	PTPN5	Tyrosine-protein phosphatase non-receptor type 5. (448 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta isoform A. (1187 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (613 aa)
	PTPRG	Protein-tyrosine-phosphatase. (879 aa)
	PTPN20	Tyrosine-protein phosphatase non-receptor type 20 isoform A. (2367 aa)
	PTP4A2	Protein tyrosine phosphatase type IVA 2. (167 aa)
	PTPN23	Tyrosine-protein phosphatase non-receptor type 23. (1589 aa)
	Y1Q_0012288	Uncharacterized protein. (180 aa)
	PTPRA-2	Uncharacterized protein. (1013 aa)
	PTPN18	Tyrosine-protein phosphatase non-receptor type 18. (493 aa)
	PTPRE	Receptor-type tyrosine-protein phosphatase epsilon isoform A. (401 aa)
	Y1Q_0006103	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	PTPRB	Receptor-type tyrosine-protein phosphatase beta. (2275 aa)
	PTPN7	Tyrosine-protein phosphatase non-receptor type 7. (339 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C isoform D. (1209 aa)
	PTPRM-2	Uncharacterized protein. (1418 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (429 aa)
	PTPN22	Tyrosine-protein phosphatase non-receptor type 22 isoform B. (579 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTPN11	PTPN6	A0A151NSB1	A0A151MCT9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.501
PTPN11	Y1Q_0006103	A0A151NSB1	A0A151N4C4	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.901
PTPN23	Y1Q_0012288	A0A151MPK8	A0A151MPR4	Tyrosine-protein phosphatase non-receptor type 23.	Uncharacterized protein.	0.920
PTPN5	PTPN7	A0A151MC61	A0A151N9F8	Tyrosine-protein phosphatase non-receptor type 5.	Tyrosine-protein phosphatase non-receptor type 7.	0.943
PTPN6	PTPN11	A0A151MCT9	A0A151NSB1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.501
PTPN6	Y1Q_0006103	A0A151MCT9	A0A151N4C4	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.499
PTPN7	PTPN5	A0A151N9F8	A0A151MC61	Tyrosine-protein phosphatase non-receptor type 7.	Tyrosine-protein phosphatase non-receptor type 5.	0.943
PTPN7	PTPRG	A0A151N9F8	A0A151MKJ0	Tyrosine-protein phosphatase non-receptor type 7.	Protein-tyrosine-phosphatase.	0.758
PTPRE	PTPRG	A0A151P4A6	A0A151MKJ0	Receptor-type tyrosine-protein phosphatase epsilon isoform A.	Protein-tyrosine-phosphatase.	0.884
PTPRG	PTPN7	A0A151MKJ0	A0A151N9F8	Protein-tyrosine-phosphatase.	Tyrosine-protein phosphatase non-receptor type 7.	0.758
PTPRG	PTPRE	A0A151MKJ0	A0A151P4A6	Protein-tyrosine-phosphatase.	Receptor-type tyrosine-protein phosphatase epsilon isoform A.	0.884
PTPRG	PTPRN	A0A151MKJ0	A0A151PD41	Protein-tyrosine-phosphatase.	Receptor-type tyrosine-protein phosphatase-like N.	0.451
PTPRG	PTPRN-2	A0A151MKJ0	A0A151NK06	Protein-tyrosine-phosphatase.	Uncharacterized protein.	0.849
PTPRN	PTPRG	A0A151PD41	A0A151MKJ0	Receptor-type tyrosine-protein phosphatase-like N.	Protein-tyrosine-phosphatase.	0.451
PTPRN-2	PTPRG	A0A151NK06	A0A151MKJ0	Uncharacterized protein.	Protein-tyrosine-phosphatase.	0.849
Y1Q_0006103	PTPN11	A0A151N4C4	A0A151NSB1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.901
Y1Q_0006103	PTPN6	A0A151N4C4	A0A151MCT9	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.499
Y1Q_0012288	PTPN23	A0A151MPR4	A0A151MPK8	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type 23.	0.920