(52 nodes) VWFC domain network (Alligator mississippiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRIM1	Cysteine-rich motor neuron 1 protein. (951 aa)
	CHRDL2	Chordin-like protein 2. (435 aa)
	CTGFB	Connective tissue growth factor b. (350 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1152 aa)
	THBS2-2	Uncharacterized protein. (1182 aa)
	CTGF	Connective tissue growth factor. (341 aa)
	KCP	Kielin/chordin-like protein isoform A. (1194 aa)
	Y1Q_0000225	Uncharacterized protein. (1391 aa)
	NELL1	Uncharacterized protein. (809 aa)
	OTOG	Uncharacterized protein. (1061 aa)
	Y1Q_0000773	Uncharacterized protein. (2242 aa)
	MUC6	Mucin-6. (2218 aa)
	MUC6-2	Uncharacterized protein. (1338 aa)
	MUC2	Intestinal mucin-like protein. (840 aa)
	Y1Q_0000777	Uncharacterized protein. (1210 aa)
	PTPRQ	Phosphatidylinositol phosphatase PTPRQ isoform G. (5845 aa)
	NELL2	Protein kinase C-binding protein NELL2. (815 aa)
	ECM2	Extracellular matrix protein 2. (747 aa)
	WISP1	WNT1-inducible-signaling pathway protein 1. (359 aa)
	VWF	Uncharacterized protein. (2826 aa)
	COL1A1	Collagen alpha-1(I) chain. (1330 aa)
	SSPO	SCO-spondin. (1367 aa)
	BMPER	BMP-binding endothelial regulator protein isoform A. (677 aa)
	VWC2	Brorin. (265 aa)
	WISP2	WNT1-inducible-signaling pathway protein 2. (251 aa)
	VWCE	Von Willebrand factor C and EGF domain-containing protein. (724 aa)
	Y1Q_0012970	VWFD domain-containing protein. (266 aa)
	TECTA-1	Alpha-tectorin. (1275 aa)
	CHRDL1	Chordin-like protein 1 isoform B. (456 aa)
	FCGBP	Uncharacterized protein. (1699 aa)
	CYR61	Protein CYR61. (374 aa)
	Y1Q_0018515	Uncharacterized protein. (1974 aa)
	COL3A1	Uncharacterized protein. (1456 aa)
	COL5A2	Uncharacterized protein. (1493 aa)
	VWC2L	Von Willebrand factor C domain-containing protein 2-like. (222 aa)
	PXDN	Peroxidasin-like protein. (354 aa)
	CHRD	Chordin. (638 aa)
	SSPOL	SCO-spondin. (1460 aa)
	NOV	NOV-like protein. (252 aa)
	THBS2	Thrombospondin-2. (1224 aa)
	Y1Q_0006527	Uncharacterized protein. (183 aa)
	KCPL	Kielin/chordin-like protein isoform A. (634 aa)
	FRAS1	Extracellular matrix protein FRAS1 isoform A. (518 aa)
	TECTA-2	Alpha-tectorin isoform B. (2619 aa)
	Y1Q_0003873	Uncharacterized protein. (1068 aa)
	DGCR2	Integral membrane protein DGCR2/IDD isoform B. (579 aa)
	Y1Q_0021924	Uncharacterized protein. (3258 aa)
	Y1Q_0021927	Uncharacterized protein. (1756 aa)
	Y1Q_0021923	Uncharacterized protein. (1808 aa)
	Y1Q_0000775	Uncharacterized protein. (2123 aa)
	JAG1-2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1147 aa)
	Y1Q_0021928	Uncharacterized protein. (2292 aa)

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMPER	CHRD	A0A151P2D8	A0A151N067	BMP-binding endothelial regulator protein isoform A.	Chordin.	0.511
CHRD	BMPER	A0A151N067	A0A151P2D8	Chordin.	BMP-binding endothelial regulator protein isoform A.	0.511
CTGF	CTGFB	A0A151M3F2	A0A151PGL6	Connective tissue growth factor.	Connective tissue growth factor b.	0.901
CTGF	CYR61	A0A151M3F2	A0A151NIY8	Connective tissue growth factor.	Protein CYR61.	0.580
CTGF	THBS2	A0A151M3F2	A0A151MUY8	Connective tissue growth factor.	Thrombospondin-2.	0.530
CTGFB	CTGF	A0A151PGL6	A0A151M3F2	Connective tissue growth factor b.	Connective tissue growth factor.	0.901
CYR61	CTGF	A0A151NIY8	A0A151M3F2	Protein CYR61.	Connective tissue growth factor.	0.580
FCGBP	MUC2	A0A151NLW7	A0A151MCG0	Uncharacterized protein.	Intestinal mucin-like protein.	0.626
JAG1	JAG1-2	A0A151M213	A0A151MGW0	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.954
JAG1-2	JAG1	A0A151MGW0	A0A151M213	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.954
KCP	KCPL	A0A151M5L8	A0A151MS86	Kielin/chordin-like protein isoform A.	Kielin/chordin-like protein isoform A.	0.914
KCPL	KCP	A0A151MS86	A0A151M5L8	Kielin/chordin-like protein isoform A.	Kielin/chordin-like protein isoform A.	0.914
MUC2	FCGBP	A0A151MCG0	A0A151NLW7	Intestinal mucin-like protein.	Uncharacterized protein.	0.626
MUC2	MUC6-2	A0A151MCG0	A0A151MCE8	Intestinal mucin-like protein.	Uncharacterized protein.	0.912
MUC6-2	MUC2	A0A151MCE8	A0A151MCG0	Uncharacterized protein.	Intestinal mucin-like protein.	0.912
OTOG	Y1Q_0006527	A0A151MC78	A0A151MTQ9	Uncharacterized protein.	Uncharacterized protein.	0.491
SSPO	Y1Q_0006527	A0A151P452	A0A151MTQ9	SCO-spondin.	Uncharacterized protein.	0.951
SSPOL	Y1Q_0000777	A0A151MZ02	A0A151MCH0	SCO-spondin.	Uncharacterized protein.	0.412
SSPOL	Y1Q_0006527	A0A151MZ02	A0A151MTQ9	SCO-spondin.	Uncharacterized protein.	0.951
THBS2	CTGF	A0A151MUY8	A0A151M3F2	Thrombospondin-2.	Connective tissue growth factor.	0.530