STRINGSTRING
Y1Q_0007761 Y1Q_0007761 HOGA1 HOGA1 RPE RPE NANS NANS ALDOC ALDOC IMPDH IMPDH QPRT-1 QPRT-1 NAGA NAGA DERA DERA ALDOC-2 ALDOC-2 GLA GLA DUS4L DUS4L NAMPT NAMPT Y1Q_0016941 Y1Q_0016941 DUS3L DUS3L TALDO1 TALDO1 IMPDH2 IMPDH2 MOCS1 MOCS1 NAPRT NAPRT GALC GALC LIAS LIAS PC PC HMGCLL1 HMGCLL1 HYAL6 HYAL6 HYAL4 HYAL4 SPAM1-1 SPAM1-1 UMPS UMPS HAO2-1 HAO2-1 DPYD DPYD DUS1L DUS1L TPI1 TPI1 HYAL1 HYAL1 HYAL2 HYAL2 HYAL3-1 HYAL3-1 ALAD ALAD HAO1 HAO1 DHX9 DHX9 ALDOA ALDOA HMGCL HMGCL GMPR GMPR DUS2 DUS2 DHODH DHODH RSAD1 RSAD1 TYW1 TYW1 RSAD2 RSAD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Y1Q_0007761Uncharacterized protein. (246 aa)
HOGA14-hydroxy-2-oxoglutarate aldolase, mitochondrial; Belongs to the DapA family. (328 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
NANSSialic acid synthase. (359 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (708 aa)
IMPDHInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (532 aa)
QPRT-1Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (330 aa)
NAGAAlpha-galactosidase. (511 aa)
DERADeoxyribose-phosphate aldolase. (318 aa)
ALDOC-2Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (357 aa)
GLAAlpha-galactosidase. (431 aa)
DUS4LtRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family. (284 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (489 aa)
Y1Q_0016941DHO_dh domain-containing protein. (169 aa)
DUS3LtRNA-dihydrouridine(47) synthase [NAD(P)(+)]. (667 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (522 aa)
MOCS1Molybdenum cofactor biosynthesis protein 1. (675 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (576 aa)
GALCGalactocerebrosidase isoform C. (637 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (387 aa)
PCPyruvate carboxylase, mitochondrial. (668 aa)
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform B. (359 aa)
HYAL6Hyaluronidase. (454 aa)
HYAL4Hyaluronidase. (507 aa)
SPAM1-1Hyaluronidase. (464 aa)
UMPSUridine 5'-monophosphate synthase. (441 aa)
HAO2-1Hydroxyacid oxidase 2 isoform B. (576 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
DUS1LtRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like isoform B. (2911 aa)
TPI1Triosephosphate isomerase. (248 aa)
HYAL1Hyaluronidase. (445 aa)
HYAL2Hyaluronidase. (474 aa)
HYAL3-1Hyaluronidase. (644 aa)
ALADDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (341 aa)
HAO1Hydroxyacid oxidase 1. (367 aa)
DHX9ATP-dependent RNA helicase A. (1546 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
HMGCLHydroxymethylglutaryl-CoA lyase, mitochondrial. (317 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (381 aa)
DUS2tRNA-dihydrouridine(20) synthase [NAD(P)+]-like. (525 aa)
DHODHDihydroorotate dehydrogenase (Quinone), mitochondrial. (166 aa)
RSAD1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (481 aa)
TYW1S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase. (721 aa)
RSAD2Radical S-adenosyl methionine domain-containing protein 2. (338 aa)
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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